Nuclear organization and chromatin dynamics - Nuclear organization and chromosome dynamics
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Teaching
Details
Faculty Faculty of Science and Medicine Domain Biology Code UE-SBL.00130 Languages English Type of lesson Lecture
Level Master Semester SA-2022 Title
French Organisation nucléaire et dynamique chromosomale German Organisation im Zellkern und Chromosomen Dynamik English Nuclear organization and chromatin dynamics - Nuclear organization and chromosome dynamics Schedules and rooms
Summary schedule Tuesday 09:15 - 11:00, Hebdomadaire (Autumn semester)
Contact's hours 8 Teaching
Responsibles Teachers Description DNA associated processes, such transcription, replication, recombination, but also chromosome pairing during meiosis occur in the context of the highly organized cell nucleus. Several structural elements of the nucleus such as the nuclear lamina or special nuclear compartments are known to regulate these processes. Changes in the nuclear organization are accompanying development and differentiation processes and defects in the nuclear architecture are known to be responsible for several human diseases. This course will focus on the elements that are shaping the nuclear architecture and their role in the activity of the genome, such as transcription, replication and DNA recombination. Since meiotic nuclei are the home of a beautiful chromosome choreography and an intense nuclear reorganisation, this course will also include an overview of the mechanisms underlying these processes. Understanding the molecular mechanisms underlying nuclear organisation and chromosome dynamics is essential for human health and fertility.
Key concepts of the lecture are nuclear architecture, chromatin domains, nuclear compartment, chromosome territories and pairing, recombination and genome stability.
Training objectives At the end of this course, the student has an overview of the nuclear organization and its role in the regulation of processes associated with the DNA. He/she is able to use this knowledge to read and analyse the specialized literature on the topic and to appreciate the research of a lab working on nuclear architecture and chromosome dynamics.)
Softskills No Off field No BeNeFri No Mobility No UniPop No -
Dates and rooms
Date Hour Type of lesson Place 18.10.2022 09:15 - 11:00 Cours PER 04, Room 0.109 25.10.2022 09:15 - 11:00 Cours PER 04, Room 0.109 08.11.2022 09:15 - 11:00 Cours PER 04, Room 0.109 15.11.2022 09:15 - 11:00 Cours PER 04, Room 0.109 22.11.2022 09:15 - 11:00 Cours PER 04, Room 0.109 -
Assessments methods
Written exam
Assessments methods By rating Descriptions of Exams Written exam (30 min.) during the semester. One mark
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Assignment
Valid for the following curricula: Additional Courses in Sciences
Version: ens_compl_sciences
Paquet indépendant des branches > Specialized courses in Biology (Master level)
Additional TDHSE programme in Biology
Version: 2022_1/V_01
Additional TDHSE Programme Requirements for BIOLOGIE E 60 or +30 > Programme 60 or +30 > Additional Programme Requirements to BIOLOGIE E+30 > Additional TDHSE programme for Biology +30 (from AS2020 on)
Additional programme requirements for PhD studies [PRE-DOC]
Version: 2020_1/v_01
Additional programme requirements for PhD studies (Faculty of Science and Medicine) > Specialized courses in Biology (Master level)
Biology +30 [MA] 30
Version: 2022_1/V_01
Minor in Biology +30 (BIOLOGY+30 for 90 ECTS) > BIOLOGY E +30, minor, Molecular life and health (from AS2021 on)
Biology [3e cycle]
Version: 2015_1/V_01
Continuing education > Specialized courses in Biology (Master level)
Biology [POST-DOC]
Version: 2015_1/V_01
Continuing education > Specialized courses in Biology (Master level)
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Version: 2022_1/V_01
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MSc in Molecular Life and Health Sciences, option Teaching 90 [MA]
Version: 2022_1/V_01
MSc in Molecular Life and Health Sciences, option Teaching, lectures and seminars (from AS2021 on) > MSc-ML, option Teaching, elective courses (from AS2021 on) > Recommended courses