Modelling human diseases in experimental genetic systems

  • Teaching

    Details

    Faculty Faculty of Science and Medicine
    Domain Biology
    Code UE-SBL.10001
    Languages English
    Type of lesson Lecture
    Level Master
    Semester SP-2023

    Title

    French Modélisation de maladies humaines dans les systèmes génétiques expérimentaux
    German Modellierung menschlicher Krankheiten in experimentellen genetischen Systemen
    English Modelling human diseases in experimental genetic systems

    Schedules and rooms

    Summary schedule Monday 10:15 - 12:00, Hebdomadaire (Spring semester)

    Teaching

    Responsibles
    • De Virgilio Claudio
    Teachers
    • Albrecht Urs
    • De Virgilio Claudio
    • Dengjel Jörn
    • Egger Boris August
    • Glauser Dominique Antoine
    • Gulli Marie-Pierre
    • Jazwinska Müller Anna
    • Nicastro Raffaele
    • Puoti Alessandro
    • Sprecher Simon
    • Wicky Collaud Chantal
    Description

    SBL.10001 Modelling human diseases in experimental genetic systems. Model organisms have long served for research on fundamental aspects of basic biology. More recently, they have also proven helpful in modeling human diseases, in the identification of drug targets, and in the evaluation of potential therapeutic agents. In this context, this course provides an overview on the most commonly used model organisms (ranging from simple eukaryotes such us budding yeast to more complex ones including nematodes, flies, zebrafish, and mice) and model systems (such as human cell cultures and organoids). We will discuss the specific advantages and limitation of each of these organisms and systems for modeling human diseases including neurodegenerative, cardiovascular, respiratory, muscular, skin, and hyperproliferative diseases including cancer. In addition, we will also delineate how these model systems can be exploited to identify molecular mechanisms and therapeutic strategies for the treatment of diverse human diseases. This lecture requires knowledge of the main genetic organisms (SBL.00119).
    Softskills
    		No
    Off field
    		No
    BeNeFri
    		Yes
    Mobility
    		No
    UniPop
    		No
  • Dates and rooms
    Date Hour Type of lesson Place
    20.02.2023 10:15 - 12:00 Cours PER 21, Room F207
    27.02.2023 10:15 - 12:00 Cours PER 21, Room F207
    06.03.2023 10:15 - 12:00 Cours PER 21, Room F207
    13.03.2023 10:15 - 12:00 Cours PER 21, Room F207
    20.03.2023 10:15 - 12:00 Cours PER 21, Room F207
    27.03.2023 10:15 - 12:00 Cours PER 21, Room F207
    03.04.2023 10:15 - 12:00 Cours PER 21, Room F207
    17.04.2023 10:15 - 12:00 Cours PER 21, Room F207
    24.04.2023 10:15 - 12:00 Cours PER 21, Room F207
    01.05.2023 10:15 - 12:00 Cours PER 21, Room F207
    08.05.2023 10:15 - 12:00 Cours PER 21, Room F207
  • Assessments methods

    Oral exam - SP-2023, Session d'été 2023

    Date 07.06.2023 08:30 - 11:30
    Assessments methods By rating
    Descriptions of Exams

    Oral (20 min.) exam. One mark.
  • Assignment
    Valid for the following curricula:
    Additional Courses in Sciences
    Version: ens_compl_sciences
    Paquet indépendant des branches > Specialized courses in Biology (Master level)
    Additional programme requirements for PhD studies [PRE-DOC]
    Version: 2020_1/v_01
    Additional programme requirements for PhD studies (Faculty of Science and Medicine) > Specialized courses in Biology (Master level)
    Biology [3e cycle]
    Version: 2015_1/V_01
    Continuing education > Specialized courses in Biology (Master level)
    Biology [POST-DOC]
    Version: 2015_1/V_01
    Continuing education > Specialized courses in Biology (Master level)
    MSc in Molecular Life and Health Sciences, option Biochemistry and Cell Biology 120 [MA]
    Version: 2022_1/V_01
    MSc in Molecular Life and Health Sciences, option Biochemistry and Cell Biology, lectures and seminars (from AS2021 on) > MSc-ML, option Biochemistry and Cell Biology, compulsory courses (from AS2021 on)
    MSc in Molecular Life and Health Sciences, option Developmental Biology and Regeneration 120 [MA]
    Version: 2022_1/V_01
    MSc in Molecular Life and Health Sciences, option Developmental Biology and Regeneration, lectures and seminars (from AS2021 on) > MSc-ML, option Developmental Biology and Regeneration, compulsory courses (from AS2021 on)
    MSc in Molecular Life and Health Sciences, option Marine Biology 120 [MA]
    Version: 2022_1/V_01
    MSc in Molecular Life and Health Sciences, option Marine Biology, lectures and seminars (from AS2021 on) > MSc-ML, option Marine Biology, elective courses (from AS2021 on) > elective courses
    MSc in Molecular Life and Health Sciences, option Neurobiology 120 [MA]
    Version: 2022_1/V_01
    MSc in Molecular Life and Health Sciences, option Neurobiology, lectures and seminars (from AS2021 on) > MSc-ML, option Neurobiology, compulsory courses (from AS2021 on)
    sp-MSc-EBR, option Infection, Inflammation and Cancer [MA] 120
    Version: 2022_1/V_01
    sp-MSc-EBR, option Infection, Inflammation and Cancer, courses and seminars (from AS2022 on) > sp-MSc-EBR, Common elective courses (from AS2022 on)
    sp-MSc-EBR, option Neuroscience [MA] 120
    Version: 2022_1/V_01
    sp-MSc-EBR, option Neuroscience, courses and seminars (from AS2022 on) > sp-MSc-EBR, Common elective courses (from AS2022 on)
    sp-MSc-EBR, option Tissue Degeneration and Regeneration [MA] 120
    Version: 2022_1/V_01
    sp-MSc-EBR, option Tissue Degeneration and Regeneration, courses and seminars (from AS2022 on) > sp-MSc-EBR, Common elective courses (from AS2022 on)