Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)—hydrogen sulfide (H2S) pathway in cancer cells
Augsburger, Fiona and Szabo, Csaba, Pharmacological Research 154.104083 (2020) | Article

Hydrogen sulfide: An endogenous regulator of the immune system
Dilek, Nahzli and Papapetropoulos, Andreas and Toliver-Kinsky, Tracy and Szabo, Csaba, Pharmacological Research 161 (2020), 105119 | Article

Blocking mineralocorticoid receptor with spironolactone may have a wide range of therapeutic actions in severe COVID-19 disease
Liaudet, Lucas and Szabo, Csaba, Critical Care (London, England) 24.1 (2020), 318 | Article

The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease
Randi, Elisa B. and Vervaet, Benjamin and Tsachaki, Maria and Porto, Elena and Vermeylen, Stijn and Lindenmeyer, Maja T. and Thuy, Le Thi Thanh and Cohen, Clemens D. and Devuyst, Olivier and Kistler, Andreas D. and Szabo, Csaba and Kawada, Norifumi and Hankeln, Thomas and Odermatt, Alex and Dewilde, Sylvia and Wenger, Roland H. and Hoogewijs, David, Antioxidants & Redox Signaling 32.16 (2020), 1155–1171 | Article

The re-emerging pathophysiological role of the cystathionine-β-synthase - hydrogen sulfide system in Down syndrome
Szabo, Csaba, The FEBS journal 287.15 (2020), 3150–3160 | Article

3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics
Abdollahi Govar, Armita and Törő, Gábor and Szaniszlo, Peter and Pavlidou, Athanasia and Bibli, Sofia-Iris and Thanki, Ketan and Resto, Vicente A. and Chao, Celia and Hellmich, Mark R. and Szabo, Csaba and Papapetropoulos, Andreas and Módis, Katalin, British Journal of Pharmacology 177.4 (2020), 866–883 | Article

Effects of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Cerulein-Induced Pancreatitis
Ahmad, Akbar and Haas De Mello, Aline and Szczesny, Bartosz and Törö, Gábor and Marcatti, Michela and Druzhyna, Nadiya and Liaudet, Lucas and Tarantini, Stefano and Salomao, Reinaldo and Garcia Soriano, Francisco and Szabo, Csaba, Shock (Augusta, Ga.) 53.5 (2020), 653–665 | Article

Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics in Murine Colon Cancer Cells
Augsburger, Fiona and Randi, Elisa B. and Jendly, Mathieu and Ascencao, Kelly and Dilek, Nahzli and Szabo, Csaba, Biomolecules 10.3 (2020), E447 | Article

Poly(ADP-ribose) polymerase inhibition: past, present and future
Curtin, Nicola J. and Szabo, Csaba, Nature Reviews. Drug Discovery 19.10 (2020), 711–736 | Article

Role of Akt Activation in PARP Inhibitor Resistance in Cancer
Gallyas, Ferenc and Sumegi, Balazs and Szabo, Csaba, Cancers 12.3 (2020), E532 | Article

Role of 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation and Cellular Bioenergetics in Human Down Syndrome Fibroblasts
Panagaki, Theodora and Randi, Elisa B. and Szabo, Csaba, Biomolecules 10.4 (2020), E653 | Article

Poly(ADP-Ribose) Polymerase Inhibition in Acute Lung Injury. A Reemerging Concept
Szabo, Csaba and Martins, Vanessa and Liaudet, Lucas, American Journal of Respiratory Cell and Molecular Biology 63.5 (2020), 571–590 | Article

Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition
Zuhra, Karim and Augsburger, Fiona and Majtan, Tomas and Szabo, Csaba, Biomolecules 10.5 (2020), E697 | Article

Oxandrolone protects against the development of multiorgan failure, modulates the systemic inflammatory response and promotes wound healing during burn injury
Ahmad, Akbar and Herndon, David N. and Szabo, Csaba, Burns: Journal of the International Society for Burn Injuries 45.3 (2019), 671–681 | Article

PARP inhibition induces Akt-mediated cytoprotective effects through the formation of a mitochondria-targeted phospho-ATM-NEMO-Akt-mTOR signalosome
Tapodi, Antal and Bognar, Zita and Szabo, Csaba and Gallyas, Ferenc and Sumegi, Balázs and Hocsak, Enikő, Biochemical Pharmacology 162 (2019), 98–108 | Article

Effect of 3-mercaptopyruvate Sulfurtransferase Deficiency on the Development of Multiorgan Failure, Inflammation, and Wound Healing in Mice Subjected to Burn Injury
Ahmad, Akbar and Druzhyna, Nadiya and Szabo, Csaba, Journal of Burn Care & Research: Official Publication of the American Burn Association 40.2 (2019), 148–156 | Article

Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis
Bibli, Sofia-Iris and Hu, Jiong and Sigala, Fragiska and Wittig, Ilka and Heidler, Juliana and Zukunft, Sven and Tsilimigras, Diamantis I. and Randriamboavonjy, Voahanginirina and Wittig, Janina and Kojonazarov, Baktybek and Schürmann, Christoph and Siragusa, Mauro and Siuda, Daniel and Luck, Bert and Abdel Malik, Randa and Filis, Konstantinos A. and Zografos, George and Chen, Chen and Wang, Dao Wen and Pfeilschifter, Josef and Brandes, Ralf P. and Szabo, Csaba and Papapetropoulos, Andreas and Fleming, Ingrid, Circulation 139.1 (2019), 101–114 | Article

Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis
Módis, Katalin and Ramanujam, V.-M. Sadagopa and Govar, Armita Abdollahi and Lopez, Ernesto and Anderson, Karl E. and Wang, Rui and Szabo, Csaba, Biochemical Pharmacology 169 (2019), 113604 | Article

The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis
Ahmad, Akbar and Vieira, Juliana de Camargo and de Mello, Aline Haas and de Lima, Thais Martins and Ariga, Suely Kubo and Barbeiro, Denise Frediani and Barbeiro, Hermes Vieira and Szczesny, Bartosz and Törö, Gábor and Druzhyna, Nadiya and Randi, Elisa B. and Marcatti, Michela and Toliver-Kinsky, Tracy and Kiss, András and Liaudet, Lucas and Salomao, Reinaldo and Soriano, Francisco Garcia and Szabo, Csaba, Pharmacological Research 145 (2019), 104263 | Article

The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock
Gröger, Michael and Wepler, Martin and Wachter, Ulrich and Merz, Tamara and McCook, Oscar and Kress, Sandra and Lukaschewski, Britta and Hafner, Sebastian and Huber-Lang, Markus and Calzia, Enrico and Georgieff, Michael and Nagahara, Noriyuki and Szabó, Csaba and Radermacher, Peter and Hartmann, Clair, Shock (Augusta, Ga.) 51.4 (2019), 472–478 | Article

The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock
Gröger, Michael and Wepler, Martin and Wachter, Ulrich and Merz, Tamara and McCook, Oscar and Kress, Sandra and Lukaschewski, Britta and Hafner, Sebastian and Huber-Lang, Markus and Calzia, Enrico and Georgieff, Michael and Nagahara, Noriyuki and Szabó, Csaba and Radermacher, Peter and Hartmann, Clair, Shock (Augusta, Ga.) 51.4 (2019), 472–478 | Article

Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects
Kiss, Tamas and Giles, Cory B. and Tarantini, Stefano and Yabluchanskiy, Andriy and Balasubramanian, Priya and Gautam, Tripti and Csipo, Tamas and Nyúl-Tóth, Ádám and Lipecz, Agnes and Szabo, Csaba and Farkas, Eszter and Wren, Jonathan D. and Csiszar, Anna and Ungvari, Zoltan, GeroScience 41.4 (2019), 419–439 | Article

Overproduction of H2S, generated by CBS, inhibits mitochondrial Complex IV and suppresses oxidative phosphorylation in Down syndrome
Panagaki, Theodora and Randi, Elisa B. and Augsburger, Fiona and Szabo, Csaba, Proceedings of the National Academy of Sciences of the United States of America 116.38 (2019), 18769–18771 | Article

H2S, a Bacterial Defense Mechanism against the Host Immune Response
Toliver-Kinsky, Tracy and Cui, Weihua and Törö, Gabor and Lee, Seung-Jin and Shatalin, Konstantin and Nudler, Evgeny and Szabo, Csaba, Infection and Immunity 87.1 (2019), e00272–18 | Article

The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock.
Gröger, Michael and Wepler, Martin and Wachter, Ulrich and Merz, Tamara and McCook, Oscar and Kress, Sandra and Lukaschewski, Britta and Hafner, Sebastian and Huber-Lang, Markus and Calzia, Enrico and others, Shock (Augusta, Ga.) (2018) | Article

Potential Pharmacological Chaperones for Cystathionine Beta-Synthase-Deficient Homocystinuria
Majtan, Tomas and Pey, Angel L and Gimenez-Mascarell, Paula and Martìnez-Cruz, Luis Alfonso and Szabo, Csaba and Kozich, Viktor and Kraus, Jan P, Targeting Trafficking in Drug Development (2018), 345–383 | Article

Protein nitration is a physiological regulator of cardiac lactate dehydrogenase active site loop mobility and activity
Nogales, Cristian and Frihoff, Jeroen and Thoenges, Detlef and Sessions, Richard B and Sickmann, Albert and Nedvetskaya, Tatiana and Ibarra-Alvarado, Cesar and Schmitz, Vera and Rosen, Peter and Goedecke, Axel and others, bioRxiv (2018), 348789 | Article

The clinically used PARP inhibitor olaparib improves organ function, suppresses inflammatory responses and accelerates wound healing in a murine model of third-degree burn injury
Ahmad, Akbar and Olah, Gabor and Herndon, David N and Szabo, Csaba, British journal of pharmacology 175.2 (2018), 232–245 | Article

Reduced adipose tissue H2S in obesity
Katsouda, Antonia and Szabo, Csaba and Papapetropoulos, Andreas, Pharmacological research 128 (2018), 190–199 | Article

Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats
Korkmaz-Icöz, Sevil and Szczesny, Bartosz and Marcatti, Michela and Li, Shiliang and Ruppert, Mihály and Lasitschka, Felix and Loganathan, Sivakkanan and Szabó, Csaba and Szabó, Gábor, British Journal of Pharmacology 175.2 (2018), 246–261 | Article

Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation
Oláh, Gabor and Módis, Katalin and Törö, Gabor and Hellmich, Mark R and Szczesny, Bartosz and Szabo, Csaba, Biochemical pharmacology 149 (2018), 186–204 | Article

A timeline of hydrogen sulfide (H2S) research: from environmental toxin to biological mediator
Szabo, Csaba, Biochemical pharmacology 149 (2018), 5–19 | Article

Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells
Untereiner, Ashley A and Pavlidou, Athanasia and Druzhyna, Nadiya and Papapetropoulos, Andreas and Hellmich, Mark R and Szabo, Csaba, Biochemical pharmacology 149 (2018), 174–185 | Article

Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases
Berger, Nathan A and Besson, Valerie C and Boulares, A Hamid and Bürkle, Alexander and Chiarugi, Alberto and Clark, Robert S and Curtin, Nicola J and Cuzzocrea, Salvatore and Dawson, Ted M and Dawson, Valina L and others, British journal of pharmacology 175.2 (2018), 192–222 | Article

Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection
Ibitokou, Samad A and Dillon, Brian E and Sinha, Mala and Szczesny, Bartosz and Delgadillo, Añahi and Abdelrahman, Doaa Reda and Szabo, Csaba and Abu-Elheiga, Lutfi and Porter, Craig and Tuvdendorj, Demidmaa and others, The Journal of Immunology 200.2 (2018), 643–656 | Article

Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant
López-Garcìa, Isabel and Gerö, Domokos and Szczesny, Bartosz and Szoleczky, Petra and Olah, Gabor and Módis, Katalin and Zhang, Kangling and Gao, Jungling and Wu, Ping and Sowers, Lawrence C and others, British journal of pharmacology 175.2 (2018), 284–300 | Article

Inventing new therapies without reinventing the wheel: the power of drug repurposing
Papapetropoulos, Andreas and Szabo, Csaba, British journal of pharmacology 175.2 (2018), 165–167 | Article

Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells
Szczesny, Bartosz and Marcatti, Michela and Ahmad, Akbar and Montalbano, Mauro and Brunyánszki, Attila and Bibli, Sofia-Iris and Papapetropoulos, Andreas and Szabo, Csaba, Scientific reports 8.1 (2018), 914 | Article

Left ventricular pressure-volume relationship in a rat model of advanced aging-associated heart failure
Pacher, Pál and Mabley, Jon G and Liaudet, Lucas and Evgenov, Oleg V and Marton, Anita and Hasko, Gyorgy and Kollai, Márk and Szabó, Csaba, American Journal of Physiology-Heart and Circulatory Physiology (2017) | Article

Hypoxia-induced Cystathionine-beta-synthase (CBS) expression: impact on colonic epithelial cells metabolism, proliferation and migration
Ches' Nique, M Phillips and Zatarain, John R and Nicholls, Michael E and Porter, Craig and Widen, Steven and Thanki, Ketan and Randall, James W and Hellmich, Judith L and Maskey, Manjit and Qiu, Suimin and others, (2017) | Misc

Upregulation of cystathionine-beta-synthase in colonic epithelia reprograms metabolism and promotes carcinogenesis
Ches' Nique, M Phillips and Zatarain, John R and Nicholls, Michael E and Porter, Craig and Widen, Steve G and Thanki, Ketan and Johnson, Paul and Jawad, Muhammad U and Moyer, Mary P and Randall, James W and others, Cancer research (2017) | Article

Alterations in nitric oxide homeostasis during traumatic brain injury
Kozlov, Andrey V and Bahrami, Soheyl and Redl, Heinz and Szabo, Csaba, Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease (2017) | Article

Hydrogen sulfide preserves eNOS function by inhibiting PYK2: implications for cardiomyocyte survival and cardioprotection
Bibli, Sofia-Iris and Szabo, Csaba and Chatzianastasiou, Athanasia and Luck, Bert and Zukunft, Sven and Fleming, Ingrid and Papapetropoulos, Andreas, Molecular Pharmacology (2017), mol–117 | Article

Cooperative Interactions Between NO and H 2 S: Chemistry, Biology, Physiology, Pathophysiology in Nitric Oxide (Third Edition)
Kevil, Christopher and Cortese-Krott, Miriam M and Nagy, Péter and Papapetropoulos, Andreas and Feelisch, Martin and Szabo, Csaba ( Elsevier, 2017), 57–83 | Chapter

H2S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells
Untereiner, Ashley A and Oláh, Gabor and Módis, Katalin and Hellmich, Mark R and Szabo, Csaba, Biochemical pharmacology 136 (2017), 86–98 | Article

Cystathionine-gamma-lyase deficient mice are protected against the development of multiorgan failure and exhibit reduced inflammatory response during burn
Ahmad, Akbar and Druzhyna, Nadiya and Szabo, Csaba, Burns 43.5 (2017), 1021–1033 | Article

Hydrogen Sulfide Preserves Endothelial Nitric Oxide Synthase Function by Inhibiting Proline-Rich Kinase 2: Implications for Cardiomyocyte Survival and Cardioprotection
Bibli, Sofia-Iris and Szabo, Csaba and Chatzianastasiou, Athanasia and Luck, Bert and Zukunft, Sven and Fleming, Ingrid and Papapetropoulos, Andreas, Molecular pharmacology 92.6 (2017), 718–730 | Article

Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: role of PYK2
Bibli, Sofia-Iris and Zhou, Zongmin and Zukunft, Sven and Fisslthaler, Beate and Andreadou, Ioanna and Szabo, Csaba and Brouckaert, Peter and Fleming, Ingrid and Papapetropoulos, Andreas, Cardiovascular research 113.8 (2017), 926–937 | Article

AQX-1125, small molecule SHIP1 activator inhibits bleomycin-induced pulmonary fibrosis
Cross, Jennifer and Stenton, Grant R and Harwig, Curtis and Szabo, Csaba and Genovese, Tiziana and Di Paola, Rosanna and Esposito, Emanuale and Cuzzocrea, Salvatore and Mackenzie, Lloyd F, British Journal of Pharmacology 174.18 (2017), 3045–3057 | Article

Vascular biology of hydrogen sulfide
Kanagy, Nancy L and Szabo, Csaba and Papapetropoulos, Andreas, American Journal of Physiology-Cell Physiology 312.5 (2017), C537–C549 | Article

Cardiovascular disease and resuscitated septic shock lead to the downregulation of the H 2 S-producing enzyme cystathionine-gamma-lyase in the porcine coronary artery
Merz, Tamara and Stenzel, Tatjana and Nußbaum, Benedikt and Wepler, Martin and Szabo, Csaba and Wang, Rui and Radermacher, Peter and McCook, Oscar, Intensive care medicine experimental 5.1 (2017), 17 | Article

Impact of hyperglycemia on cystathionine-gamma-lyase expression during resuscitated murine septic shock
Merz, Tamara and Vogt, Josef A and Wachter, Ulrich and Calzia, Enrico and Szabo, Csaba and Wang, Rui and Radermacher, Peter and McCook, Oscar, Intensive care medicine experimental 5.1 (2017), 30 | Article

Inhibition of mitochondrial bioenergetics by esterase-triggered COS/H2S donors
Steiger, Andrea K and Marcatti, Michela and Szabo, Csaba and Szczesny, Bartosz and Pluth, Michael D, ACS chemical biology 12.8 (2017), 2117–2123 | Article

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors
Szabo, Csaba and Papapetropoulos, Andreas, Pharmacological reviews 69.4 (2017), 497–564 | Article

Consensus Molecular Subtypes of Colorectal Cancer and their Clinical Implications.
Thanki, Ketan and Nicholls, Michael Edward and Gajjar, Aakash and Senagore, Anthony J and Qiu, Suimin and Szabo, Csaba and Hellmich, Mark R and Chao, Celia, International biological and biomedical journal 3.3 (2017), 105–111 | Article

BACTERIAL HYDROGEN SULFIDE CONFERS RESISTANCE TO THE IMMUNE SYSTEM in SHOCK
Toliver-Kinsky, Tracy and Cui, Weihua and Toro, Gabor and Szabo, Csaba ( LIPPINCOTT WILLIAMS & WILKINS TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA …, 2017), 22–22 | Chapter

Role of hydrogen sulfide in critical illness
Szabo, Csaba, Free Radical Biology and Medicine 96 (2016), S4–S5 | Article

Both the H2S biosynthesis inhibitor aminooxyacetic acid and the mitochondrially targeted H2S donor AP39 exert protective effects in a mouse model of burn injury
Ahmad, Akbar and Szabo, Csaba, Pharmacological research 113 (2016), 348–355 | Article

Mitochondrial poly (ADP-ribose) polymerase: the Wizard of Oz at work
Brunyanszki, Attila and Szczesny, Bartosz and Virág, László and Szabo, Csaba, Free Radical Biology and Medicine 100 (2016), 257–270 | Article

Cystathionine-beta-synthase inhibition for colon cancer: enhancement of the efficacy of aminooxyacetic acid via the prodrug approach
Chao, Celia and Zatarain, John R and Ding, Ye and Coletta, Ciro and Mrazek, Amy A and Druzhyna, Nadiya and Johnson, Paul and Chen, Haiying and Hellmich, Judy L and Asimakopoulou, Antonia and others, Molecular Medicine 22 (2016), 361 | Article

Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine beta-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer
Druzhyna, Nadiya and Szczesny, Bartosz and Olah, Gabor and Módis, Katalin and Asimakopoulou, Antonia and Pavlidou, Athanasia and Szoleczky, Petra and Gerö, Domokos and Yanagi, Kazunori and Törö, Gabor and others, Pharmacological research 113 (2016), 18–37 | Article

Regulation and role of endogenously produced hydrogen sulfide in angiogenesis
Katsouda, Antonia and Bibli, Sofia-Iris and Pyriochou, Anastasia and Szabo, Csaba and Papapetropoulos, Andreas, Pharmacological research 113 (2016), 175–185 | Article

S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics
Módis, Katalin and Ju, YoungJun and Ahmad, Akbar and Untereiner, Ashley A and Altaany, Zaid and Wu, Lingyun and Szabo, Csaba and Wang, Rui, Pharmacological research 113 (2016), 116–124 | Article

Sepsis induces telomere shortening: a potential mechanism responsible for delayed pathophysiological events in sepsis survivors?
Oliveira, Naara Mendes and Rios, Ester CS and de Lima, Thais Martins and Victorino, Vanessa Jacob and Barbeiro, Hermes and da Silva, Fabiano Pinheiro and Szabo, Csaba and Soriano, Francisco Garcia, Molecular Medicine 22 (2016), 886 | Article

Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics
Szczesny, Bartosz and Marcatti, Michela and Zatarain, John R and Druzhyna, Nadiya and Wiktorowicz, John E and Nagy, Péter and Hellmich, Mark R and Szabo, Csaba, Scientific reports 6 (2016), 36125 | Article

Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide
Zhou, Zongmin and Martin, Emil and Sharina, Iraida and Esposito, Iolanda and Szabo, Csaba and Bucci, Mariarosaria and Cirino, Giuseppe and Papapetropoulos, Andreas, Pharmacological research 111 (2016), 556–562 | Article

AP39, a mitochondrially-targeted hydrogen sulfide donor, exerts protective effects in renal epithelial cells subjected to oxidative stress in vitro and in acute renal injury in vivo
Ahmad, Akbar and Olah, Gabor and Szczesny, Bartosz and Wood, Mark E and Whiteman, Matthew and Szabo, Csaba, Shock (Augusta, Ga.) 45.1 (2016), 88 | Article

Delayed treatment with sodium hydrosulfide improves regional blood flow and alleviates cecal ligation and puncture (CLP)-induced septic shock
Ahmad, Akbar and Druzhyna, Nadiya and Szabo, Csaba, Shock (Augusta, Ga.) 46.2 (2016), 183 | Article

Effect of endotoxemia in mice genetically deficient in cystathionine-gamma-lyase, cystathionine-beta-synthase or 3-mercaptopyruvate sulfurtransferase
Ahmad, Akbar and Gerö, Domokos and Olah, Gabor and Szabo, Csaba, International journal of molecular medicine 38.6 (2016), 1683–1692 | Article

Cardioprotection by H2S donors: nitric oxide-dependent and-independent mechanisms
Chatzianastasiou, Athanasia and Bibli, Sofia-Iris and Andreadou, Ioanna and Efentakis, Panagiotis and Kaludercic, Nina and Wood, Mark E and Whiteman, Matthew and Di Lisa, Fabio and Daiber, Andreas and Manolopoulos, Vangelis G and others, Journal of Pharmacology and Experimental Therapeutics 358.3 (2016), 431–440 | Article

Glucocorticoids suppress mitochondrial oxidant production via upregulation of uncoupling protein 2 in hyperglycemic endothelial cells
Gerö, Domokos and Szabo, Csaba, PloS one 11.4 (2016), e0154813 | Article

Hydrogen sulfide contributes to retinal neovascularization in ischemia-induced retinopathy
Gersztenkorn, David and Coletta, Ciro and Zhu, Shuang and Ha, Yonju and Liu, Hua and Tie, Hongyan and Zhou, Jia and Szabo, Csaba and Zhang, Wenbo and Motamedi, Massoud, Investigative ophthalmology & visual science 57.7 (2016), 3002–3009 | Article

Intraluminal flagellin differentially contributes to gut dysbiosis and systemic inflammation following burn injury
Grimes, Logan and Doyle, Allie and Miller, Aaron L and Pyles, Richard B and Olah, Gabor and Szabo, Csaba and Hoskins, Sarah and Eaves-Pyles, Tonyia, PloS one 11.12 (2016), e0166770 | Article

Hydrogen sulfide is an antiviral and antiinflammatory endogenous gasotransmitter in the airways. Role in respiratory syncytial virus infection
Ivanciuc, Teodora and Sbrana, Elena and Ansar, Maria and Bazhanov, Nikolay and Szabo, Csaba and Casola, Antonella and Garofalo, Roberto P, American journal of respiratory cell and molecular biology 55.5 (2016), 684–696 | Article

Differential acute and chronic effects of burn trauma on murine skeletal muscle bioenergetics
Porter, Craig and Herndon, David N and Bhattarai, Nisha and Ogunbileje, John O and Szczesny, Bartosz and Szabo, Csaba and Toliver-Kinsky, Tracy and Sidossis, Labros S, Burns 42.1 (2016), 112–122 | Article

Hydrogen sulfide modulates chromatin remodeling and inflammatory mediator production in response to endotoxin, but does not play a role in the development of endotoxin tolerance
Rios, Ester CS and Soriano, Francisco G and Olah, Gabor and Gerö, Domokos and Szczesny, Bartosz and Szabo, Csaba, Journal of Inflammation 13.1 (2016), 10 | Article

Gasotransmitters in cancer: from pathophysiology to experimental therapy
Szabo, Csaba, Nature Reviews Drug Discovery 15.3 (2016), 185 | Article

Hydrogen sulfide, an enhancer of vascular nitric oxide signaling: mechanisms and implications
Szabo, Csaba, American Journal of Physiology-Cell Physiology 312.1 (2016), C3–C15 | Article

H2S and cancer: Give credit where credit is due in Urologic Oncology: Seminars and Original Investigations
Szabo, Csaba ( Elsevier, 2016), 334 | Chapter

3-Mercaptopyruvate sulfurtransferase deficient mice show accelerated glucose uptake and a dysregulated metabolic profile
Gero, Domokos and Ahmad, Akbar and Brunyanszki, Attila and Olah, Gabor and Szczesny, Bartosz and Szabo, Csaba, Nitric Oxide 47 (2015), S35–S36 | Article

Role of hydrogen sulfide in paramyxovirus infections
Li, Hui and Ma, Yinghong and Escaffre, Oliver and Ivanciuc, Teodora and Komaravelli, Narayana and Kelley, John P and Coletta, Ciro and Szabo, Csaba and Rockx, Barry and Garofalo, Roberto P and others, Journal of virology (2015), JVI–00264 | Article

Selectivity of hydrogen sulfide toward cyclic nucleotide phosphodiesterases
Panopoulos, Panagiotis and Yang, Guangdong and Asimakopoulou, Antonia and Topouzis, Stavros and Wang, Rui and Szabo, Csaba and Papapetropoulos, Andreas, Nitric Oxide 47 (2015), S39 | Article

Systemic infection and combined burn and infection: Contribution of host-derived and bacteria-derived hydrogen sulfide production to bacterial clearance
Toliver-Kinsky, Tracy and Shatalin, Konstantin and Nudler, Evgeny and Szabo, Csaba, Nitric Oxide 47 (2015), S46–S47 | Article

MD-2 is required for disulfide HMGB1–dependent TLR4 signaling
Yang, Huan and Wang, Haichao and Ju, Zhongliang and Ragab, Ahmed A and Lundbäck, Peter and Long, Wei and Valdes-Ferrer, Sergio I and He, Mingzhu and Pribis, John P and Li, Jianhua and others, Journal of Experimental Medicine (2015), jem–20141318 | Article

Hydrogen sulfide and cancer in Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide
Hellmich, Mark R and Szabo, Csaba ( Springer, 2015), 233–241 | Chapter

inhibition of Eikenella corrodens lysine decarboxylase by tranexamic acid and its effects on gingival inflammation in humans: p0161
Lohinai, Z and Keremi, B and Szoko, E and Tabi, T and Szabo, C and Tulassay, Z and Dicesare, JC and Davis, CA and Collins, LM and Levine, M, Journal of Clinical Periodontology 42 (2015), 114 | Article

Old dog, new tricks: proangiogenic effect of adenosine via stimulation of thrombospondin-1 in macrophages
Szabo, Csaba, Journal of leukocyte biology 97.1 (2015), 3–5 | Article

Hydrogen sulfide and PKG in ischemia–reperfusion injury: sources, signaling, accelerators and brakes
Andreadou, Ioanna and Iliodromitis, Efstathios K and Szabo, Csaba and Papapetropoulos, Andreas, Basic research in cardiology 110.5 (2015), 52 | Article

Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway
Bibli, Sofia-Iris and Andreadou, Ioanna and Chatzianastasiou, Athanasia and Tzimas, Christos and Sanoudou, Despina and Kranias, Evangelia and Brouckaert, Peter and Coletta, Ciro and Szabo, Csaba and Kremastinos, Dimitrios Th and others, Cardiovascular research 106.3 (2015), 432–442 | Article

Upregulation and Mitochondrial Sequestration of Hemoglobin Occur in Circulating Leukocytes during Critical Illness, Conferring a Cytoprotective Phenotype
Brunyanszki, Attila and Erdelyi, Katalin and Szczesny, Bartosz and Olah, Gabor and Salomao, Reinaldo and Herndon, David N and Szabo, Csaba, Molecular Medicine 21.1 (2015), 666 | Article

Regulation of vascular tone, angiogenesis and cellular bioenergetics by the 3-mercaptopyruvate sulfurtransferase/H2S pathway: functional impairment by hyperglycemia and restoration by DL-alpha-lipoic acid
Coletta, Ciro and Módis, Katalin and Szczesny, Bartosz and Brunyánszki, Attila and Oláh, Gábor and Rios, Ester CS and Yanagi, Kazunori and Ahmad, Akbar and Papapetropoulos, Andreas and Szabo, Csaba, Molecular Medicine 21.1 (2015), 1 | Article

Salvage of nicotinamide adenine dinucleotide plays a critical role in the bioenergetic recovery of post-hypoxic cardiomyocytes
Gero, Domokos and Szabo, Csaba, British journal of pharmacology 172.20 (2015), 4817–4832 | Article

The therapeutic potential of cystathionine beta-synthetase/hydrogen sulfide inhibition in cancer
Hellmich, Mark R and Coletta, Ciro and Chao, Celia and Szabo, Csaba, Antioxidants & redox signaling 22.5 (2015), 424–448 | Article

Biofilm lysine decarboxylase, a new therapeutic target for periodontal inflammation
Lohinai, Zsolt and Keremi, Beata and Szöko, Eva and Tábi, Tamás and Szabo, Csaba and Tulassay, Zsolt and DiCesare, John C and Davis, Carole A and Collins, Lindsay M and Levine, Martin, Journal of periodontology 86.10 (2015), 1176–1184 | Article

Differentiation-associated downregulation of poly (ADP-ribose) polymerase-1 expression in myoblasts serves to increase their resistance to oxidative stress
Oláh, Gábor and Szczesny, Bartosz and Brunyánszki, Attila and López-Garcìa, Isabel A and Gerö, Domokos and Radák, Zsolt and Szabo, Csaba, PLoS One 10.7 (2015), e0134227 | Article

Severe burn injury induces thermogenically functional mitochondria in murine white adipose tissue
Porter, Craig and Herndon, David N and Bhattarai, Nisha and Ogunbileje, John O and Szczesny, Bartosz and Szabo, Csaba and Toliver-Kinsky, Tracy and Sidossis, Labros S, Shock (Augusta, Ga.) 44.3 (2015), 258 | Article

The HIV Protease Inhibitor Saquinavir Inhibits HMGB1-Driven Inflammation by Targeting the Interaction of Cathepsin V with TLR4/MyD88
Pribis, John P and Al-Abed, Yousef and Yang, Huan and Gero, Domokos and Xu, Hongbo and Montenegro, Marcelo F and Bauer, Eileen M and Kim, Sodam and Chavan, Sangeeta S and Cai, Changchun and others, Molecular Medicine 21.1 (2015), 749 | Article

Hydrogen sulfide attenuates cytokine production through the modulation of chromatin remodeling
Rios, Ester and Szczesny, Bartosz and Soriano, Francisco G and Olah, Gabor and Szabo, Csaba, International journal of molecular medicine 35.6 (2015), 1741–1746 | Article

Overexpression of cystathionine gamma-lyase suppresses detrimental effects of spinocerebellar ataxia type 3
Snijder, Pauline M and Baratashvili, Madina and Grzeschik, Nicola A and Leuvenink, Henri GD and Kuijpers, Lucas and Huitema, Sippie and Schaap, Onno and Giepmans, Ben NG and Kuipers, Jeroen and Miljkovic, Jan Lj and others, Molecular Medicine 21.1 (2015), 758 | Article

Time-dependent and organ-specific changes in mitochondrial function, mitochondrial DNA integrity, oxidative stress and mononuclear cell infiltration in a mouse model of burn injury
Szczesny, Bartosz and Brunyánszki, Attila and Ahmad, Akbar and Oláh, Gabor and Porter, Craig and Toliver-Kinsky, Tracy and Sidossis, Labros and Herndon, David N and Szabo, Csaba, PloS one 10.12 (2015), e0143730 | Article

The role of H2S bioavailability in endothelial dysfunction
Wang, Rui and Szabo, Csaba and Ichinose, Fumito and Ahmed, Asif and Whiteman, Matthew and Papapetropoulos, Andreas, Trends in pharmacological sciences 36.9 (2015), 568–578 | Article

Regulation of mitochondrial poly (ADP-Ribose) polymerase activation by the beta-adrenoceptor/cAMP/protein kinase A axis during oxidative stress
Brunyanszki, Attila and Olah, Gabor and Coletta, Ciro and Szczesny, Bartosz and Szabo, Csaba, Molecular pharmacology (2014), mol–114 | Article

Sulfide-inhibition of mitochondrial respiration at very low oxygen concentrations
Matallo, J and Vogt, J and McCook, O and Wachter, U and Tillmans, F and Groeger, M and Szabo, C and Georgieff, M and Radermacher, P and Calzia, E, Nitric Oxide 41 (2014), 79–84 | Article

H2S during circulatory shock: some unresolved questions
McCook, Oscar and Radermacher, Peter and Volani, Chiara and Asfar, Pierre and Ignatius, Anita and Kemmler, Julia and Möller, Peter and Szabó, Csaba and Whiteman, Matthew and Wood, Mark E and others, Nitric Oxide 41 (2014), 48–61 | Article

Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-beta-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro
Módis, Katalin and Coletta, Ciro and Asimakopoulou, Antonia and Szczesny, Bartosz and Chao, Celia and Papapetropoulos, Andreas and Hellmich, Mark R and Szabo, Csaba, Nitric oxide 41 (2014), 146–156 | Article

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects
Módis, Katalin and Bos, Eelke M and Calzia, Enrico and van Goor, Harry and Coletta, Ciro and Papapetropoulos, Andreas and Hellmich, Mark R and Radermacher, Peter and Bouillaud, Frédéric and Szabo, Csaba, British journal of pharmacology 171.8 (2014), 2123–2146 | Article

AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro
Szczesny, Bartosz and Módis, Katalin and Yanagi, Kazunori and Coletta, Ciro and Le Trionnaire, Sophie and Perry, Alexis and Wood, Mark E and Whiteman, Matthew and Szabo, Csaba, Nitric oxide 41 (2014), 120–130 | Article

Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal ligation and puncture
Coletta, Ciro and Módis, Katalin and Oláh, Gábor and Brunyánszki, Attila and Herzig, Daniela S and Sherwood, Edward R and Ungvári, Zoltán and Szabo, Csaba, Critical care 18.5 (2014), 511 | Article

Modulation of poly (ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes
Gerö, Domokos and Szoleczky, Petra and Chatzianastasiou, Athanasia and Papapetropoulos, Andreas and Szabo, Csaba, Molecular medicine 20.1 (2014), 313 | Article

The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor,(10-oxo-10-(4-(3-thioxo-3 H-1, 2-dithiol-5-yl) phenoxy) decyl) triphenylphosphonium bromide (AP39)
Le Trionnaire, Sophie and Perry, Alexis and Szczesny, Bartosz and Szabo, Csaba and Winyard, Paul G and Whatmore, Jacqueline L and Wood, Mark E and Whiteman, Matthew, MedChemComm 5.6 (2014), 728–736 | Article

Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis
Mukhopadhyay, Partha and Rajesh, Mohanraj and Cao, Zongxian and Horváth, Béla and Park, Ogyi and Wang, Hua and Erdelyi, Katalin and Holovac, Eileen and Wang, Yuping and Liaudet, Lucas and others, Hepatology 59.5 (2014), 1998–2009 | Article

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms
Szabo, Csaba and Ransy, Céline and Módis, Katalin and Andriamihaja, Mireille and Murghes, Baptiste and Coletta, Ciro and Olah, Gabor and Yanagi, Kazunori and Bouillaud, Frédéric, British journal of pharmacology 171.8 (2014), 2099–2122 | Article

Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function
Szczesny, Bartosz and Brunyanszki, Attila and Olah, Gabor and Mitra, Sankar and Szabo, Csaba, Nucleic acids research 42.21 (2014), 13161–13173 | Article

Selectivity of commonly used pharmacological inhibitors for cystathionine beta synthase (CBS) and cystathionine gamma lyase (CSE)
Asimakopoulou, Antonia and Panopoulos, Panagiotis and Chasapis, Christos T and Coletta, Ciro and Zhou, Zongmin and Cirino, Giuseppe and Giannis, Athanassios and Szabo, Csaba and Spyroulias, Georgios A and Papapetropoulos, Andreas, British journal of pharmacology 169.4 (2013), 922–932 | Article

Characterization of AQX-1125, a small-molecule SHIP1 activator: part 2. Efficacy studies in allergic and pulmonary inflammation models in vivo
Stenton, Grant R and Mackenzie, Lloyd F and Tam, Patrick and Cross, Jennifer L and Harwig, Curtis and Raymond, Jeffrey and Toews, Judy and Chernoff, David and MacRury, Thomas and Szabo, Csaba, British journal of pharmacology 168.6 (2013), 1519–1529 | Article

P45 Circulating hydrogen sulfide is stored as labile sulfurs in albumin
Wesseling, Sebastiaan and Abrahams, Alferso C and Szabo, Csaba and Goor, Harry v and Joles, Jaap A, Nitric Oxide 31 (2013), S55 | Article

Potential role of hydrogen sulfide in the pathogenesis of vascular dysfunction in septic shock
Coletta, Ciro and Szabo, Csaba, Current vascular pharmacology 11.2 (2013), 208–221 | Article

Therapeutic applications of PARP inhibitors: anticancer therapy and beyond
Curtin, Nicola J and Szabo, Csaba, Molecular aspects of medicine 34.6 (2013), 1217–1256 | Article

Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis
Eaves-Pyles, Tonyia and Patel, Jignesh and Arigi, Emma and Cong, Yingzi and Cao, Anthony and Garg, Nisha and Dhiman, Monisha and Pyles, Richard B and Arulanandam, Bernard and Miller, Aaron L and others, Molecular Medicine 19.1 (2013), 263 | Article

Role of poly (ADP-ribosyl) ation in a ‘two-hit’model of hypoxia and oxidative stress in human A549 epithelial cells in vitro
Erdélyi, Katalin and Pacher, Pál and Virág, László and Szabó, Csaba, International journal of molecular medicine 32.2 (2013), 339–346 | Article

Cell-based screening identifies paroxetine as an inhibitor of diabetic endothelial dysfunction
Gerö, Domokos and Szoleczky, Petra and Suzuki, Kunihiro and Módis, Katalin and Oláh, Gabor and Coletta, Ciro and Szabo, Csaba, Diabetes 62.3 (2013), 953–964 | Article

Identification of pharmacological modulators of HMGB1-induced inflammatory response by cell-based screening
Gerö, Domokos and Szoleczky, Petra and Módis, Katalin and Pribis, John P and Al-Abed, Yousef and Yang, Huan and Chevan, Sangeeta and Billiar, Timothy R and Tracey, Kevin J and Szabo, Csaba, PLoS One 8.6 (2013), e65994 | Article

Q50, an iron-chelating and zinc-complexing agent, improves cardiac function in rat models of ischemia/reperfusion-induced myocardial injury
Korkmaz, Sevil and Barnucz, Eniko and Loganathan, Sivakkanan and Li, Shiliang and Radovits, Tamás and Hegedus, Péter and Zubarevich, Alina and Hirschberg, Kristóf and Weymann, Alexander and Puskás, László G and others, Circulation Journal 77.7 (2013), 1817–1826 | Article

Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury
Módis, Katalin and Gerö, Domokos and Stangl, Rita and Rosero, Olivér and Szijártó, Attila and Lotz, Gábor and Mohácsik, Petra and Szoleczky, Petra and Coletta, Ciro and Szabó, Csaba, International journal of molecular medicine 31.2 (2013), 437–446 | Article

Hydrogen sulfide-mediated stimulation of mitochondrial electron transport involves inhibition of the mitochondrial phosphodiesterase 2A, elevation of cAMP and activation of protein kinase A
Módis, Katalin and Panopoulos, Panagiotis and Coletta, Ciro and Papapetropoulos, Andreas and Szabo, Csaba, Biochemical pharmacology 86.9 (2013), 1311–1319 | Article

Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics
Módis, Katalin and Coletta, Ciro and Erdélyi, Katalin and Papapetropoulos, Andreas and Szabo, Csaba, The FASEB Journal 27.2 (2013), 601–611 | Article

Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway
Módis, Katalin and Asimakopoulou, Antonia and Coletta, Ciro and Papapetropoulos, Andreas and Szabo, Csaba, Biochemical and biophysical research communications 433.4 (2013), 401–407 | Article

Characterization of AQX-1125, a small-molecule SHIP1 activator
Stenton, Grant R and Mackenzie, Lloyd F and Tam, Patrick and Cross, Jennifer L and Harwig, Curtis and Raymond, Jeffrey and Toews, Judy and Wu, Joyce and Ogden, Nancy and MacRury, Thomas and others, British journal of pharmacology 168.6 (2013), 1506–1518 | Article

Endogenously produced hydrogen sulfide supports tumor cell growth and proliferation
Szabo, Csaba and Hellmich, Mark R, Cell Cycle 12.18 (2013), 2915–2916 | Article

Tumor-derived hydrogen sulfide, produced by cystathionine-beta-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer
Szabo, Csaba and Coletta, Ciro and Chao, Celia and Módis, Katalin and Szczesny, Bartosz and Papapetropoulos, Andreas and Hellmich, Mark R, Proceedings of the National Academy of Sciences 110.30 (2013), 12474–12479 | Article

Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage
Szczesny, Bartosz and Olah, Gabor and Walker, Dillon K and Volpi, Elena and Rasmussen, Blake B and Szabo, Csaba and Mitra, Sankar, PLoS One 8.9 (2013), e75201 | Article

Efficacy of a novel SHIP1 activator in animals and healthy human volunteers exposed to inhaled lipopolysaccharide
Chernoff, David and Tam, Patrick and Mackenzie, Lloyd and Toews, Judy and Stenton, Grant and Harwig, Curtis and Raymond, Jeffrey and Brown, Vanessa and Smith, Stephen and Elborn, Stuart and others, (2012) | Misc

'Professor Galveston'has departed. Obituary-Daniel Traber
Prough, Donald S and Enhkbaatar, Perenlei and Szabo, Csaba, (2012) | Misc

Effects of intravenous sulfide during resuscitated porcine hemorrhagic shock
Bracht, Hendrik and Scheuerle, Angelika and Gröger, Michael and Hauser, Balázs and Matallo, José and McCook, Oscar and Seifritz, Andrea and Wachter, Ulrich and Vogt, Josef A and Asfar, Pierre and others, Critical care medicine 40.7 (2012), 2157–2167 | Article

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation
Coletta, Ciro and Papapetropoulos, Andreas and Erdelyi, Katalin and Olah, Gabor and Módis, Katalin and Panopoulos, Panagiotis and Asimakopoulou, Antonia and Gerö, Domokos and Sharina, Iraida and Martin, Emil and others, Proceedings of the National Academy of Sciences 109.23 (2012), 9161–9166 | Article

Temperature and cell-type dependency of sulfide effects on mitochondrial respiration
Groeger, Michael and Matallo, Jose and McCook, Oscar and Wagner, Florian and Wachter, Ulrich and Bastian, Olga and Gierer, Saskia and Reich, Vera and Stahl, Bettina and Huber-Lang, Markus and others, Shock 38.4 (2012), 367–374 | Article

Time profile of oxidative stress and neutrophil activation in ovine acute lung injury and sepsis
Lange, Matthias and Szabo, Csaba and Traber, Daniel L and Horvath, Eszter and Hamahata, Atsumori and Nakano, Yoshimitsu and Traber, Lillian D and Cox, Robert A and Schmalstieg, Frank C and Herndon, David N and others, Shock (Augusta, Ga.) 37.5 (2012), 468 | Article

Bacterial lysine decarboxylase influences human dental biofilm lysine content, biofilm accumulation, and subclinical gingival inflammation
Lohinai, Zsolt and Keremi, Beata and Szoko, Eva and Tabi, Tamas and Szabo, Csaba and Tulassay, Zsolt and Levine, Martin, Journal of periodontology 83.8 (2012), 1048–1056 | Article

Combined recombinant human activated protein C and ceftazidime prevent the onset of acute respiratory distress syndrome in severe sepsis
Maybauer, Marc O and Maybauer, Dirk M and Fraser, John F and Westphal, Martin and Szabó, Csaba and Cox, Robert A and Hawkins, Hal K and Traber, Lillian D and Traber, Daniel L, Shock 37.2 (2012), 170–176 | Article

Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress
Módis, Katalin and Gerö, Domokos and Erdélyi, Katalin and Szoleczky, Petra and DeWitt, Douglas and Szabo, Csaba, Biochemical pharmacology 83.5 (2012), 633–643 | Article

Effects of FP15, a peroxynitrite decomposition catalyst on cardiac and pulmonary function after cardiopulmonary bypass
Radovits, Tamás and Beller, Carsten J and Groves, John T and Merkely, Béla and Karck, Matthias and Szabó, Csaba and Szabó, Gábor, European Journal of Cardio-Thoracic Surgery 41.2 (2012), 391–396 | Article

Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation
Szabó, Gábor and Loganathan, Sivakkanan and Merkely, Béla and Groves, John T and Karck, Matthias and Szabó, Csaba and Radovits, Tamás, The Journal of thoracic and cardiovascular surgery 143.6 (2012), 1443–1449 | Article

The outsiders: emerging roles of ectonucleotidases in inflammation
Szabo, Csaba and Pacher, Pal, Science translational medicine 4.146 (2012), 146ps14–146ps14 | Article

Roles of hydrogen sulfide in the pathogenesis of diabetes mellitus and its complications
Szabo, Csaba, Antioxidants & redox signaling 17.1 (2012), 68–80 | Article

Identification of agents that reduce renal hypoxia–reoxygenation injury using cell-based screening: Purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia
Szoleczky, Petra and Módis, Katalin and Nagy, Nóra and Tóth, Zoltán Dóri and DeWitt, Douglas and Szabó, Csaba and Gerö, Domokos, Archives of biochemistry and biophysics 517.1 (2012), 53–70 | Article

Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients
Tucsek, Zsuzsanna and Gautam, Tripti and Sonntag, William E and Toth, Peter and Saito, Hiroshi and Salomao, Reinaldo and Szabo, Csaba and Csiszar, Anna and Ungvari, Zoltan, Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences 68.6 (2012), 652–660 | Article

Nebulization with gamma-tocopherol ameliorates acute lung injury after burn and smoke inhalation in the ovine model
Yamamoto, Yusuke and Enkhbaatar, Perenlei and Sousse, Linda E and Sakurai, Hiroyuki and Rehberg, Sebastian W and Asmussen, Sven and Kraft, Edward R and Wright, Charlotte L and Bartha, Eva and Cox, Robert A and others, Shock (Augusta, Ga.) 37.4 (2012), 408 | Article

Thioglycine and L-thiovaline: biologically active H2S-donors
Zhou, Zongmin and von Wantoch Rekowski, Margarete and Coletta, Ciro and Szabo, Csaba and Bucci, Mariarosaria and Cirino, Giuseppe and Topouzis, Stavros and Papapetropoulos, Andreas and Giannis, Athanassios, Bioorganic & medicinal chemistry 20.8 (2012), 2675–2678 | Article

The peroxynitrite catalyst WW-85 improves pulmonary function in ovine septic shock
Maybauer, Dirk M and Maybauer, Marc O and Szabó, Csaba and Cox, Robert A and Westphal, Martin and Kiss, Levente and Horvath, Eszter M and Traber, Lillian D and Hawkins, Hal K and Salzman, Andrew L and others, Shock (Augusta, Ga.) 35.2 (2011) | Article

Role of nitric oxide in the development of vascular contractile dysfunction in circulatory shock
Szabo, Csaba and Wu, Chin-Chen, J Med Sci 31.1 (2011), 001–016 | Article

INCREASED POLY (ADP-RIBOSYL) ATION IN CIRCULATING LEUKOCYTES AND SKELETAL MUSCLE TISSUE OF PEDIATRIC PATIENTS in SHOCK
Erdelyi, K and Olah, G and Finnerty, C and Sbrana, E and Gero, D and Herndon, DN and Szabo, C ( LIPPINCOTT WILLIAMS & WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA, 2011), 72–72 | Chapter

The angiotensin-converting enzyme inhibitor captopril inhibits poly (ADP-ribose) polymerase activation and exerts beneficial effects in an ovine model of burn and smoke injury
Asmussen, Sven and Bartha, Eva and Olah, Gabor and Sbrana, Elena and Rehberg, Sebastian W and Yamamoto, Yusuke and Enkhbaatar, Perenlei and Hawkins, Hal K and Ito, Hiroshi and Cox, Robert A and others, Shock (Augusta, Ga.) 36.4 (2011), 402 | Article

Burn and smoke injury activates poly (ADP-ribose) polymerase in circulating leukocytes
Bartha, Eva and Asmussen, Sven and Olah, Gabor and Rehberg, Sebastian W and Yamamoto, Yusuke and Traber, Daniel L and Szabo, Csaba, Shock (Augusta, Ga.) 36.2 (2011), 144 | Article

Regulation of kinase cascade activation and heat shock protein expression by poly (ADP-ribose) polymerase inhibition in doxorubicin-induced heart failure
Bartha, Eva and Solti, Izabella and Szabo, Aliz and Olah, Gabor and Magyar, Klara and Szabados, Eszter and Kalai, Tamas and Hideg, Kalman and Toth, Kalman and Gero, Domokos and others, Journal of cardiovascular pharmacology 58.4 (2011), 380–391 | Article

Effects of coronary revascularization with or without cardiopulmonary bypass on plasma levels of asymmetric dimethylarginine
Cziráki, Attila and Ajtay, Zénó and Németh, ádám and Lenkey, Zsófia and Sulyok, Endre and Szabados, Sándor and Alotti, Nasri and Martens-Lobenhoffer, Jens and Szabó, Csaba and Bode-Böger, Stefanie M, Coronary artery disease 22.4 (2011), 245–252 | Article

Human internal thoracic artery grafts exhibit severe morphological and functional damage and spasmic vasomotion due to oxidative stress
Kiss, Levente and Benkö, Rita and Kovacs, Endre and Szerafin, Tamas and Modis, Katalin and Szabo, Csaba and Lacza, Zsombor, Medical science monitor: international medical journal of experimental and clinical research 17.7 (2011), CR411 | Article

Inhibition of nitric oxide–stimulated vasorelaxation by carbon monoxide-releasing molecules
Marazioti, Antonia and Bucci, Mariarosaria and Coletta, Ciro and Vellecco, Valentina and Baskaran, Padmamalini and Szabó, Csaba and Cirino, Giuseppe and Marques, Ana Rita and Guerreiro, Bruno and Gonçalves, Ana ML and others, Arteriosclerosis, thrombosis, and vascular biology 31.11 (2011), 2570–2576 | Article

The peroxynitrite catalyst WW-85 improves microcirculation in ovine smoke inhalation injury and septic shock
Maybauer, Dirk M and Maybauer, Marc O and Szabó, Csaba and Westphal, Martin and Traber, Lillian D and Salzman, Andrew L and Herndon, David N and Traber, Daniel L, Burns 37.5 (2011), 842–850 | Article

Cytoprotective effect of gamma-tocopherol against tumor necrosis factor alpha induced cell dysfunction in L929 cells
Oláh, Gabor and Módis, Katalin and Gerö, Domokos and Suzuki, Kunihiro and Dewitt, Douglas and Traber, Daniel L and Szabó, Csaba, International journal of molecular medicine 28.5 (2011), 711–720 | Article

Increased poly (ADP-ribosyl) ation in skeletal muscle tissue of pediatric patients with severe burn injury: prevention by propranolol treatment
Oláh, Gábor and Finnerty, Celeste and Sbrana, Elena and Elijah, Itoro and Gerö, Domokos and Herndon, David and Szabó, Csaba, Shock (Augusta, Ga.) 36.1 (2011), 18 | Article

Effects of intravenous sulfide during porcine aortic occlusion-induced kidney ischemia/reperfusion injury
Simon, Florian and Scheuerle, Angelika and Gröger, Michael and Stahl, Bettina and Wachter, Ulrich and Vogt, Josef and Speit, Günter and Hauser, Balázs and Möller, Peter and Calzia, Enrico and others, Shock 35.2 (2011), 156–163 | Article

Effects of a potent peroxynitrite decomposition catalyst in murine models of endotoxemia and sepsis
Soriano, Francisco Garcia and Lorigados, Clara Batista and Pacher, Pal and Szabó, Csaba, Shock (Augusta, Ga.) 35.6 (2011), 560 | Article

Reduction of liver ischemia-reperfusion injury via glutamine pretreatment
Stangl, Rita and Szijártó, Attila and ónody, Péter and Tamás, Judit and Tátrai, Miklós and Hegedüs, Viktor and Blázovics, Anna and Lotz, Gábor and Kiss, András and Módis, Katalin and others, Journal of Surgical Research 166.1 (2011), 95–103 | Article

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function
Suzuki, Kunihiro and Olah, Gabor and Modis, Katalin and Coletta, Ciro and Kulp, Gabriella and Gerö, Domokos and Szoleczky, Petra and Chang, Tuanjie and Zhou, Zongmin and Wu, Lingyun and others, Proceedings of the National Academy of Sciences 108.33 (2011), 13829–13834 | Article

Cardioprotective effects of hydrogen sulfide
Szabó, Gábor and Veres, Gábor and Radovits, Tamás and Gerö, Domokos and Módis, Katalin and Miesel-Gröschel, Christiane and Horkay, Ferenc and Karck, Matthias and Szabó, Csaba, Nitric Oxide 25.2 (2011), 201–210 | Article

Endothelial dysfunction as predictor of mortality in sepsis
Szabo, Csaba and Goldstein, Brahm, Critical care medicine 39.4 (2011), 878–879 | Article

Hydrogen sulphide and angiogenesis: mechanisms and applications
Szabó, Csaba and Papapetropoulos, Andreas, British journal of pharmacology 164.3 (2011), 853–865 | Article

Cardiopulmonary, histologic, and inflammatory effects of intravenous Na2S after blunt chest trauma-induced lung contusion in mice
Wagner, Florian and Scheuerle, Angelika and Weber, Sandra and Stahl, Bettina and McCook, Oscar and Knöferl, Markus W and Huber-Lang, Markus and Seitz, Daniel H and Thomas, Jörg and Asfar, Pierre and others, Journal of Trauma and Acute Care Surgery 71.6 (2011), 1659–1667 | Article

Effects of stent implementation on plasma levels of asymmetric dimethylarginine in patients with or without ST-segment elevation acute myocardial infarction
Ajtay, Zéno and Németh, ádám and Sulyok, Endre and Cziráki, Attila and Szabados, Sandor and Martens-Lobenhoffer, Jeans and Awiszus, Friedemann and Szabó, Csaba and Bode-Böger, Stefanie M, International journal of molecular medicine 25.4 (2010), 617–624 | Article

Pathomechanisms of myocardial dysfunction in sepsis
Batista Lorigados, Clara and Garcia Soriano, Francisco and Szabo, Csaba, Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets-Immune, Endocrine & Metabolic Disorders) 10.3 (2010), 274–284 | Article

Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice
Baumgart, Katja and Wagner, Florian and Gröger, Michael and Weber, Sandra and Barth, Eberhard and Vogt, Josef A and Wachter, Ulrich and Huber-Lang, Markus and Knöferl, Markus W and Albuszies, Gerd and others, Critical care medicine 38.2 (2010), 588–595 | Article

Beneficial pulmonary effects of a metalloporphyrinic peroxynitrite decomposition catalyst in burn and smoke inhalation injury
Lange, Matthias and Szabo, Csaba and Enkhbaatar, Perenlei and Connelly, Rhykka and Horvath, Eszter and Hamahata, Atsumori and Cox, Robert A and Esechie, Aimalohi and Nakano, Yoshimitsu and Traber, Lillian D and others, American Journal of Physiology-Lung Cellular and Molecular Physiology 300.2 (2010), L167–L175 | Article

Recombinant human activated protein C attenuates cardiovascular and microcirculatory dysfunction in acute lung injury and septic shock
Maybauer, Marc O and Maybauer, Dirk M and Fraser, John F and Szabo, Csaba and Westphal, Martin and Kiss, Levente and Horvath, Eszter M and Nakano, Yoshimitsu and Herndon, David N and Traber, Lillian D and others, Critical Care 14.6 (2010), R217 | Article

Endotoxin tolerance: selective alterations in gene expression and protection against lymphocyte death
Melo, Edielle S and Goloubkova, Tatiana and Barbeiro, Denise F and Gorjão, Renata and Vasconcelos, Dewton and Szabo, Csaba and Curi, Rui and de Lima Salgado, Thais Martins and Velasco, Irineu T and Soriano, Francisco G, Immunobiology 215.6 (2010), 435–442 | Article

Gene expression reprogramming protects macrophage from septic-induced cell death
Melo, Edielle Sant’Anna and Barbeiro, Denise F and Gorjão, Renata and Rios, Ester Correia Sarmento and Vasconcelos, Dewton and Velasco, Irineu T and Szabo, Csaba and Curi, Rui and de Lima-Salgado, Thais Martins and Soriano, Francisco Garcia, Molecular immunology 47.16 (2010), 2587–2593 | Article

Effect of hydrogen sulfide on myocardial protection in the setting of cardioplegia and cardiopulmonary bypass
Osipov, Robert M and Robich, Michael P and Feng, Jun and Chan, Vincent and Clements, Richard T and Deyo, Ralph J and Szabo, Csaba and Sellke, Frank W, Interactive cardiovascular and thoracic surgery 10.4 (2010), 506–512 | Article

A cell-microelectronic sensing technique for the screening of cytoprotective compounds
ózsvári, Béla and Puskás, László G and Nagy, Lajos I and Kanizsai, Iván and Gyuris, Márió and Madácsi, Ramóna and Fehér, Liliána Z and Gerö, Domokos and Szabó, Csaba, International journal of molecular medicine 25.4 (2010), 525–530 | Article

Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
Roberts, Ruth A and Smith, Robert A and Safe, Stephen and Szabo, Csaba and Tjalkens, Ronald B and Robertson, Fredika M, Toxicology 276.2 (2010), 85–94 | Article

Therapeutic injection of PARP inhibitor INO-1001 preserves cardiac function in porcine myocardial ischemia and reperfusion without reducing infarct size
Roesner, Jan P and Mersmann, Jan and Bergt, Stefan and Bohnenberg, Karl and Barthuber, Carmen and Szabo, Csaba and Nöldge-Schomburg, Gabriele EF and Zacharowski, Kai, Shock 33.5 (2010), 507–512 | Article

Influence of PARP-1 polymorphisms in patients after traumatic brain injury
Sarnaik, Ajit A and Conley, Yvette P and Okonkwo, David O and Barr, Taura L and Fink, Ericka L and Szabo, Csaba and Kochanek, Patrick M and Clark, Robert SB, Journal of neurotrauma 27.3 (2010), 465–471 | Article

Gaseotransmitters: new frontiers for translational science
Szabo, Csaba, Science translational medicine 2.59 (2010), 59ps54–59ps54 | Article

Pathophysiological roles of peroxynitrite in circulatory shock
Szabó, Csaba and Módis, Katalin, Shock (Augusta, Ga.) 34.0 1 (2010), 4 | Article

Detection of exhaled hydrogen sulphide gas in healthy human volunteers during intravenous administration of sodium sulphide
Toombs, Christopher F and Insko, Michael A and Wintner, Edward A and Deckwerth, Thomas L and Usansky, Helen and Jamil, Khurram and Goldstein, Brahm and Cooreman, Michael and Szabo, Csaba, British journal of clinical pharmacology 69.6 (2010), 626–636 | Article

A monobromobimane-based assay to measure the pharmacokinetic profile of reactive sulphide species in blood
Wintner, Edward A and Deckwerth, Thomas L and Langston, William and Bengtsson, Asa and Leviten, Dina and Hill, Paul and Insko, Michael A and Dumpit, Ronald and VandenEkart, Emily and Toombs, Christopher F and others, British journal of pharmacology 160.4 (2010), 941–957 | Article

Peroxynitrite: Biochemistry, toxicology and development of therapeutics
Szabo, Csaba, Toxicology Letters 189 (2009), S22 | Article

Hydrogen Sulfide: A Metabolic Modulator and a Protective Agent in Animal Models of Reperfusion Injury in Intensive Care Medicine
Szabó, C and Asfar, P and Radermacher, P ( Springer, 2009), 171–179 | Chapter

Poly (ADP-ribose) polymerase mediates inflammation in a mouse model of contact hypersensitivity.
Bai, Peter and Hegedus, Csaba and Szabo, Eva and Gyüre, László and Bakondi, Edina and Brunyánszki, Attila and Gergely, Szabolcs and Szabo, Csaba and Virag, Laszlo, The Journal of investigative dermatology 129.1 (2009), 234–238 | Article

Inhibition of neuronal nitric oxide synthase in ovine model of acute lung injury
Enkhbaatar, Perenlei and Connelly, Rhykka and Wang, Jianpu and Nakano, Yoshimitsu and Lange, Matthias and Hamahata, Atsumori and Horvath, Eszter and Szabo, Csaba and Jaroch, Stefan and Hölscher, Peter and others, Critical care medicine 37.1 (2009) | Article

Stent placement in patients with coronary heart disease decreases plasma levels of the endogenous nitric oxide synthase inhibitor ADMA
Ajtay, Zénó and Scalera, Fortunato and Cziráki, Attila and Horváth, Iván and Papp, Lajos and Sulyok, Endre and Szabo, Csaba and Martens-Lobenhoffer, Jens and Awiszus, Friedemann and Bode-Böger, Stefanie M, International journal of molecular medicine 23.5 (2009), 651–657 | Article

Alpha7 cholinergic-agonist prevents systemic inflammation and improves survival during resuscitation
Cai, Bolin and Chen, Fei and Ji, Yan and Kiss, Levente and de Jonge, Wouter J and Conejero-Goldberg, Concepcion and Szabo, Csaba and Deitch, Edwin A and Ulloa, Luis, Journal of cellular and molecular medicine 13.9b (2009), 3774–3785 | Article

Anti-inflammatory adjuvant in resuscitation fluids improves survival in hemorrhage
Cai, Bolin and Chen, Fei and Lin, Xingchun and Miller, Edmund and Szabo, Csaba and Deithch, Edwin A and Ulloa, Lusi, Critical care medicine 37.3 (2009), 860–868 | Article

Dual role of poly (ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells
Erdélyi, Katalin and Bai, Péter and Kovács, István and Szabó, éva and Mocsár, Gábor and Kakuk, Annamária and Szabó, Csaba and Gergely, Pál and Virág, László, The FASEB Journal 23.10 (2009), 3553–3563 | Article

Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn-and smoke-induced acute lung injury
Esechie, Aimalohi and Enkhbaatar, Perenlei and Traber, Daniel L and Jonkam, Collette and Lange, Matthias and Hamahata, Atsumori and Djukom, Clarisse and Whorton, Elbert B and Hawkins, Hal K and Traber, Lillian D and others, British journal of pharmacology 158.6 (2009), 1442–1453 | Article

Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide
Insko, Michael A and Deckwerth, Thomas L and Hill, Paul and Toombs, Christopher F and Szabo, Csaba, British journal of pharmacology 157.6 (2009), 944–951 | Article

Activation of the cholinergic antiinflammatory pathway reduces ricin-induced mortality and organ failure in mice
Mabley, Jon G and Pacher, Pal and Szabo, Csaba, Molecular Medicine 15.5-6 (2009), 166 | Article

The novel inosine analogue INO-2002 exerts an anti-inflammatory effect in a murine model of acute lung injury
Mabley, Jon G and Pacher, Pal and Murthy, Kanneganti GK and Williams, William and Southan, Garry J and Salzman, Andrew L and Szabo, Csaba, Shock (Augusta, Ga.) 32.3 (2009), 258 | Article

Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis
Módis, Katalin and Gerö, Domokos and Nagy, Nóra and Szoleczky, Petra and Tóth, Zoltán Dóri and Szabó, Csaba, British journal of pharmacology 158.6 (2009), 1565–1578 | Article

Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro
Mukhopadhyay, Partha and Rajesh, Mohanraj and Bátkai, Sándor and Kashiwaya, Yoshihiro and Haskó, György and Liaudet, Lucas and Szabó, Csaba and Pacher, Pál, American Journal of Physiology-Heart and Circulatory Physiology 296.5 (2009), H1466–H1483 | Article

Effect of hydrogen sulfide in a porcine model of myocardial ischemia-reperfusion: comparison of different administration regimens and characterization of the cellular mechanisms of protection
Osipov, Robert M and Robich, Michael P and Feng, Jun and Liu, Yuhong and Clements, Richard T and Glazer, Hilary P and Sodha, Neel R and Szabo, Csaba and Bianchi, Cesario and Sellke, Frank W, Journal of cardiovascular pharmacology 54.4 (2009), 287–297 | Article

Intra-mitochondrial poly (ADP-ribosyl) ation: potential role for alpha-ketoglutarate dehydrogenase
Pankotai, Eszter and Lacza, Zsombor and Murányi, Marianna and Szabó, Csaba, Mitochondrion 9.2 (2009), 159–164 | Article

Hydrogen sulfide is an endogenous stimulator of angiogenesis
Papapetropoulos, Andreas and Pyriochou, Anastasia and Altaany, Zaid and Yang, Guangdong and Marazioti, Antonia and Zhou, Zongmin and Jeschke, Mark G and Branski, Ludwik K and Herndon, David N and Wang, Rui and others, Proceedings of the National Academy of Sciences 106.51 (2009), 21972–21977 | Article

Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy
Rajesh, Mohanraj and Mukhopadhyay, Partha and Bátkai, Sándor and Mukhopadhyay, Bani and Patel, Vivek and Haskó, György and Szabó, Csaba and Mabley, Jon G and Liaudet, Lucas and Pacher, Pál, Journal of cellular and molecular medicine 13.8b (2009), 2330–2341 | Article

Poly (ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes
Reinemund, Jana and Seidel, Kerstin and Steckelings, Ulrike M and Zaade, Daniela and Klare, Sabrina and Rompe, Franziska and Katerbaum, Marlen and Schacherl, Jens and Li, Yaosi and Menk, Mario and others, Biochemical pharmacology 77.12 (2009), 1795–1805 | Article

Molecular biological effects of selective neuronal nitric oxide synthase inhibition in ovine lung injury
Saunders, Fiona D and Westphal, Martin and Enkhbaatar, Perenlei and Wang, Jianpu and Pazdrak, Konrad and Nakano, Yoshimitsu and Hamahata, Atsumori and Jonkam, Collette C and Lange, Matthias and Connelly, Rhykka L and others, American Journal of Physiology-Lung Cellular and Molecular Physiology 298.3 (2009), L427–L436 | Article

Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury
Sodha, Neel R and Clements, Richard T and Feng, Jun and Liu, Yuhong and Bianchi, Cesario and Horvath, Eszter M and Szabo, Csaba and Stahl, Gregory L and Sellke, Frank W, The Journal of thoracic and cardiovascular surgery 138.4 (2009), 977–984 | Article

Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction
Szabo, Csaba, British journal of pharmacology 156.5 (2009), 713–727 | Article

Bench-to-bedside review: Hydrogen sulfide–the third gaseous transmitter: applications for critical care
Wagner, Florian and Asfar, Pierre and Calzia, Enrico and Radermacher, Peter and Szabó, Csaba, Critical care 13.3 (2009), 213 | Article

Use of mono-bromo-bimane to derivatize sulfide in whole blood: comparison of blood sulfide levels during atmospheric hydrogen sulfide exposure and intravenous sulfide infusion
Bengtsson, Asa and Johnson, Jeff and Hill, Paul and Mulligan, Joanne and Leviten, Dina and Insko, Michael and Mebel, Elise and Vertz, Peter and VandenEkart, Emily and Szabo, Csaba and others, (2008) | Misc

The hydrogen sulfide donor IK-1001 stimulates neovascularization and improves wound healing
Pyiochou, Anastasia and Papapetropoulos, Andreas and Olah, Gabor and Wintner, Edward and Jeschke, Marc and Branski, Ludwik and Herndon, David and Traber, Daniel and Szabo, Csaba, (2008) | Misc

Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation
Esechie, Aimalohi and Kiss, Levente and Olah, Gabor and Horváth, Eszter M and Hawkins, Hal and Szabo, Csaba and Traber, Daniel L, Clinical Science 115.3 (2008), 91–97 | Article

Quantification of poly (ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury
Fink, Ericka L and Lai, Yichen and Zhang, Xiaopeng and Janesko-Feldman, Keri and Adelson, P David and Szabó, Csaba and Berger, Rachel P and Sarnaik, Ajit A and Kochanek, Patrick M and Clark, Robert SB, Journal of Cerebral Blood Flow & Metabolism 28.9 (2008), 1523–1529 | Article

Poly (ADP-ribose) polymerase: a new therapeutic target?
Gerö, Domokos and Szabo, Csaba, Current Opinion in Anesthesiology 21.2 (2008), 111–121 | Article

Reduction of hemorrhagic transformation by PJ34, a poly (ADP-ribose) polymerase inhibitor, after permanent focal cerebral ischemia in mice
Haddad, Marianne and Beray-Berthat, Virginie and Coqueran, Bérard and Palmier, Bruno and Szabo, Csaba and Plotkine, Michel and Margaill, Isabelle, European journal of pharmacology 588.1 (2008), 52–57 | Article

gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury
Hamahata, Atsumori and Enkhbaatar, Perenlei and Kraft, Edward R and Lange, Matthias and Leonard, Scott W and Traber, Maret G and Cox, Robert A and Schmalstieg, Frank C and Hawkins, Hal K and Whorton, Elbert B and others, Free Radical Biology and Medicine 45.4 (2008), 425–433 | Article

Protein kinase C protects from DNA damage-induced necrotic cell death by inhibiting poly (ADP-ribose) polymerase-1
Hegedüs, Csaba and Lakatos, Petra and Oláh, Gábor and Tóth, Balázs I and Gergely, Szabolcs and Szabó, éva and Bìró, Tamás and Szabó, Csaba and Virág, László, FEBS letters 582.12 (2008), 1672–1678 | Article

Treatment with insulin inhibits poly (ADP-ribose) polymerase activation in a rat model of endotoxemia
Horváth, Eszter M and Benkö, Rita and Gerö, Domonkos and Kiss, Levente and Szabó, Csaba, Life sciences 82.3-4 (2008), 205–209 | Article

Hydrogen sulfide decreases adenosine triphosphate levels in aortic rings and leads to vasorelaxation via metabolic inhibition
Kiss, Levente and Deitch, Edwin A and Szabó, Csaba, Life sciences 83.17-18 (2008), 589–594 | Article

Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury
Lai, Yichen and Chen, Yaming and Watkins, Simon C and Nathaniel, Paula D and Guo, Fengli and Kochanek, Patrick M and Jenkins, Larry W and Szabó, Csaba and Clark, Robert SB, Journal of neurochemistry 104.6 (2008), 1700–1711 | Article

The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes
Mabley, Jon G and Pacher, Pal and Murthy, Kanneganti GK and Williams, William and Southan, Garry J and Salzman, Andrew L and Szabo, Csaba, Journal of Endocrinology 198.3 (2008), 581–589 | Article

Lung-protective effects of the metalloporphyrinic peroxynitrite decomposition catalyst WW-85 in interleukin-2 induced toxicity
Maybauer, Dirk M and Maybauer, Marc O and Szabó, Csaba and Westphal, Martin and Traber, Lillian D and Enkhbaatar, Perenlei and Murthy, Kanneganti GK and Nakano, Yoshimitsu and Salzman, Andrew L and Herndon, David N and others, Biochemical and biophysical research communications 377.3 (2008), 786–791 | Article

Poly (ADP) ribose synthetase inhibition in alveolar macrophages undergoing hypoxia and reoxygenation
McCourtie, Anton S and Farivar, Alexander S and Woolley, Steven M and Merry, Heather E and Wolf, Patrick S and Szabo, Csaba and Mulligan, Michael S, Experimental and molecular pathology 84.2 (2008), 141–144 | Article

Role of the peroxynitrite-poly (ADP-ribose) polymerase pathway in human disease
Pacher, Pal and Szabo, Csaba, The American journal of pathology 173.1 (2008), 2–13 | Article

Inhibition of angiogenesis by the poly (ADP-ribose) polymerase inhibitor PJ-34
Pyriochou, Anastasia and Olah, Gabor and Deitch, Edwin A and Szabó, Csaba and Papapetropoulos, Andreas, International journal of molecular medicine 22.1 (2008), 113–118 | Article

Improvement of aging-associated cardiovascular dysfunction by the orally administered copper (II)-aspirinate complex
Radovits, Tamás and Gerö, Domokos and Lin, Li-ni and Loganathan, Sivakkanan and Hoppe-Tichy, Torsten and Szabó, Csaba and Karck, Matthias and Sakurai, Hiromu and Szabó, Gábor, Rejuvenation research 11.5 (2008), 945–956 | Article

Hemodynamic and metabolic effects of hydrogen sulfide during porcine ischemia/reperfusion injury
Simon, Florian and Giudici, Riccardo and Duy, Cuong Nguyen and Schelzig, Hubert and öter, Sükrü and Gröger, Michael and Wachter, Ulrich and Vogt, Josef and Speit, Günter and Szabó, Csaba and others, Shock 30.4 (2008), 359–364 | Article

The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia–reperfusion injury
Sodha, Neel R and Clements, Richard T and Feng, Jun and Liu, Yuhong and Bianchi, Cesario and Horvath, Eszter M and Szabo, Csaba and Sellke, Frank W, European Journal of Cardio-Thoracic Surgery 33.5 (2008), 906–913 | Article

Neuronal nitric oxide synthase inhibition attenuates cardiopulmonary dysfunctions after combined burn and smoke inhalation injury in sheep
Westphal, Martin and Enkhbaatar, Perenlei and Schmalstieg, Frank C and Kulp, Gabriela A and Traber, Lillian D and Morita, Naoki and Cox, Robert A and Hawkins, Hal K and Westphal-Varghese, Beena B and Rudloff, Helen E and others, Critical care medicine 36.4 (2008), 1196–1204 | Article

Poly (ADP-ribose) polymerase as a drug target for cardiovascular disease and cancer: an update
Horváth, Eszter M and Szabó, Csaba, Drug News Perspect 20.3 (2007), 171–181 | Article

Poly (ADP-ribose) polymerase activation and circulatory shock in Novartis Foundation symposium
Szabó, Csaba ( Chichester; New York; John Wiley; 1999, 2007), 92 | Chapter

Protein tyrosine nitration and poly (ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: implication for cytotoxicity
Bai, Péter and Hegedüs, Csaba and Erdélyi, Katalin and Szabó, éva and Bakondi, Edina and Gergely, Szabolcs and Szabó, Csaba and Virág, László, Toxicology letters 170.3 (2007), 203–213 | Article

Opposite effects of vascular irradiation on inflammatory response and apoptosis induction in the vessel wall layers via the peroxynitrite-poly (ADP-ribose) polymerase pathway
Beller, Carsten J and Horvath, Eszter and Kosse, Jens and Becker, Alexander and Radovits, Tamás and Krempien, Robert and Berger, Irina and Hagl, Siegfried and Szabó, Csaba and Szabó, Gábor, Clinical Research in Cardiology 96.1 (2007), 8–16 | Article

Local administration of the poly (ADP-ribose) polymerase inhibitor INO-1001 prevents NAD+ depletion and improves water maze performance after traumatic brain injury in mice
Clark, Robert SB and Vagni, Vincent A and Nathaniel, Paula D and Jenkins, Larry W and Dixon, C Edward and Szabó, Csaba, Journal of neurotrauma 24.8 (2007), 1399–1405 | Article

Human heart mitochondria do not produce physiologically relevant quantities of nitric oxide
Csordás, Attila and Pankotai, Eszter and Snipes, James A and Cselenyák, Attila and Sárszegi, Zsolt and Cziráki, Attila and Gaszner, Balázs and Papp, Lajos and Benkö, Rita and Kiss, Levente and others, Life sciences 80.7 (2007), 633–637 | Article

Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function
Elrod, John W and Calvert, John W and Morrison, Joanna and Doeller, Jeannette E and Kraus, David W and Tao, Ling and Jiao, Xiangying and Scalia, Rosario and Kiss, Levente and Szabo, Csaba and others, Proceedings of the National Academy of Sciences 104.39 (2007), 15560–15565 | Article

Oxidant-induced cardiomyocyte injury: identification of the cytoprotective effect of a dopamine 1 receptor agonist using a cell-based high-throughput assay
Gerö, Domokos and Módis, Katalin and Nagy, Nóra and Szoleczky, Petra and Tóth, Zoltán Dóri and Dormán, György and Szabó, Csaba, International journal of molecular medicine 20.5 (2007), 749–761 | Article

Reactive oxygen species mediate a cellular ‘memory’of high glucose stress signalling
Ihnat, MA and Thorpe, JE and Kamat, CD and Szabo, C and Green, DE and Warnke, LA and Lacza, Z and Cselenyak, A and Ross, K and Shakir, S and others, Diabetologia 50.7 (2007), 1523–1531 | Article

Contribution of poly (ADP-ribose) polymerase to postischemic blood—brain barrier damage in rats
Lenzsér, Gábor and Kis, Béla and Snipes, James A and Gáspár, Tamás and Sándor, Péter and Komjáti, Katalin and Szabo, Csaba and Busija, David W, Journal of Cerebral Blood Flow & Metabolism 27.7 (2007), 1318–1326 | Article

Inhibition of poly (adenosine diphosphate-ribose) polymerase by the active form of vitamin D
Mabley, Jon G and Wallace, Rebecca and Pacher, Pál and Murphy, Kanneganti and Szabó, Csaba, International journal of molecular medicine 19.6 (2007), 947–952 | Article

The selective poly (ADP) ribose-polymerase 1 inhibitor INO1001 reduces spinal cord injury during porcine aortic cross-clamping-induced ischemia/reperfusion injury
Maier, Christian and Scheuerle, Angelika and Hauser, Balázs and Schelzig, Hubert and Szabó, Csaba and Radermacher, Peter and Kick, Jochen, Intensive care medicine 33.5 (2007), 845–850 | Article

Adenosine receptor activation ameliorates type 1 diabetes
Németh, Zoltán H and Bleich, David and Csóka, Balázs and Pacher, Pál and Mabley, Jon G and Himer, Leonóra and Vizi, E Sylvester and Deitch, Edwin A and Szabó, Csaba and Cronstein, Bruce N and others, The FASEB Journal 21.10 (2007), 2379–2388 | Article

Role of poly (ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors
Pacher, Pál and Szabó, Csaba, Cardiovascular drug reviews 25.3 (2007), 235–260 | Article

Primary role of superoxide anion generation in the cascade of events leading to endothelial dysfunction and damage in high glucose treated HUVEC
Quagliaro, Lisa and Piconi, Ludovica and Assaloni, Roberta and Da Ros, Roberto and Szabó, Csaba and Ceriello, Antonio, Nutrition, metabolism and cardiovascular diseases 17.4 (2007), 257–267 | Article

The peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction
Radovits, Tamás and Seres, Leila and Gerö, Domokos and Lin, Li-ni and Beller, Carsten J and Chen, Song-He and Zotkina, Julia and Berger, Irina and Groves, John T and Szabó, Csaba and others, Mechanisms of ageing and development 128.2 (2007), 173–181 | Article

Poly (ADP-Ribose) polymerase inhibition improves endothelial dysfunction induced by hypochlorite
Radovits, Tamás and Zotkina, Julia and Lin, Li-Ni and Bömicke, Timo and Arif, Rawa and Gerö, Domokos and Horváth, Eszter M and Karck, Matthias and Szabo, Csaba and Szabo, Gabor, Experimental Biology and Medicine 232.9 (2007), 1204–1212 | Article

Poly (ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro
Radovits, Tamás and Lin, Li-ni and Zotkina, Julia and Gerö, Domokos and Szabó, Csaba and Karck, Matthias and Szabó, Gábor, European journal of pharmacology 564.1-3 (2007), 158–166 | Article

Single dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction
Radovits, Tamás and Seres, Leila and Gerö, Domokos and Berger, Irina and Szabó, Csaba and Karck, Matthias and Szabó, Gábor, Experimental gerontology 42.7 (2007), 676–685 | Article

S-nitrosoglutathione-containing hydrogel increases dermal blood flow in streptozotocin-induced diabetic rats
Seabra, AB and Pankotai, E and Fehér, M and Somlai, A and Kiss, L and Biro, L and Szabo, C and Kollai, M and De Oliveira, MG and Lacza, Z, British Journal of Dermatology 156.5 (2007), 814–818 | Article

Cytoprotective and anti-inflammatory effects of hydrogen sulfide in macrophages and mice
Szabó, C and Kiss, L and Pankotai, E, Critical Care 11.2 (2007), P2 | Article

Hydrogen sulphide and its therapeutic potential
Szabó, Csaba, Nature reviews Drug discovery 6.11 (2007), 917 | Article

Infusion of sodium sulfide improves myocardial and endothelial function in a canine model of cardiopulmonary bypass
Szabó, C and Veres, G and Radovits, T and Karck, M and Szabó, G, Critical Care 11.2 (2007), P1 | Article

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
Szabó, Csaba and Ischiropoulos, Harry and Radi, Rafael, Nature reviews Drug discovery 6.8 (2007), 662 | Article

Effect of PJ-34 PARP-inhibitor on rat liver microcirculation and antioxidant status
Szijártó, Attila and Batmunkh, Enkhjargal and Hahn, Oszkár and Mihály, Zoltán and Kreiss, Adám and Kiss, András and Lotz, Gábor and Schaff, Zsuzsa and Váli, László and Blázovics, Anna and others, Journal of Surgical Research 142.1 (2007), 72–80 | Article

Short-term alanyl-glutamine dipeptide pretreatment in liver ischemia–reperfusion model: effects on microcirculation and antioxidant status in rats
Szijártó, Attila and Hahn, Oszkár and Batmunkh, Enkhjargal and Stangl, Rita and Kiss, András and Lotz, Gábor and Schaff, Zsuzsa and Váli, László and Blázovics, Anna and Gero, Domokos and others, Clinical Nutrition 26.5 (2007), 640–648 | Article

Adenosine Receptors: Therapeutic Aspects for Inflammatory and Immune Diseases
Hasko, Gyorgy and Szabo, Csaba and Cronstein, Bruce N ( CRC Press, 2006) | Book

The world according to poly (ADP-ribose) polymerase (PARP)—update 2006
Barth, Eberhard and Radermacher, Peter and Szabó, Csaba, (2006) | Misc

4 Regulation of Monocyte/Macrophage Function by Adenosine
Haskó, György and Szabó, Csaba, Adenosine Receptors: Therapeutic Aspects for Inflammatory and Immune Diseases (2006), 49 | Article

Ros from Both Mitochondrial and Extra-mitochondrial Sources Mediates a Long-term Persistence of High Glucose Stress after Glucose Normalization: 724-p
Ihnat, Michael A and Thorpe, Jessica E and Szabo, Csaba and Warnke, Linda A and Lacza, Zsombor and Cselenyák, Attila and Picont, Ludo-vica and Kaltreider, Ronald C and Ceriello, Antonio and Ihnt, Michael, Diabetes 55 (2006), A171 | Article

Activation of the peroxynitrite-poly (adenosine diphosphate-ribose) polymerase pathway during neointima proliferation: a new target to prevent restenosis after endarterectomy
Beller, Carsten J and Radovits, Tamás and Kosse, Jens and Gerö, Domokos and Szabó, Csaba and Szabó, Gábor, Journal of vascular surgery 43.4 (2006), 824–830 | Article

Poly (ADP-ribose) polymerase inhibition combined with irradiation: a dual treatment concept to prevent neointimal hyperplasia after endarterectomy
Beller, Carsten J and Kosse, Jens and Radovits, Tamás and Gerö, Domokos and Krempien, Robert and Gross, Marie-Luise and Berger, Irina and Hagl, Siegfried and Szabó, Csaba and Szabó, Gábor, International Journal of Radiation Oncology* Biology* Physics 66.3 (2006), 867–875 | Article

Poly (ADP-ribose) polymerase inhibition reverses vascular dysfunction after gamma-irradiation
Beller, Carsten J and Radovits, Tamás and Seres, Leila and Kosse, Jens and Krempien, Robert and Gross, Marie-Luise and Penzel, Roland and Berger, Irina and Huber, Peter E and Hagl, Siegfried and others, International Journal of Radiation Oncology* Biology* Physics 65.5 (2006), 1528–1535 | Article

MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells
Diana, Z Ye and Tai, Mei-Hui and Linning, Katrina D and Szabo, Csaba and Olson, L Karl, Diabetes 55.3 (2006), 742–750 | Article

Role of the peroxynitrite-poly (ADP-ribose) polymerase pathway in the pathogenesis of liver injury
Gero, Domokos and Szabo, Csaba, Current pharmaceutical design 12.23 (2006), 2903–2910 | Article

Anti-inflammatory effects of PJ34, a poly (ADP-ribose) polymerase inhibitor, in transient focal cerebral ischemia in mice
Haddad, M and Rhinn, Hervé and Bloquel, Carole and Coqueran, B and Szabo, C and Plotkine, Michel and Scherman, Daniel and Margaill, Isabelle, British journal of pharmacology 149.1 (2006), 23–30 | Article

The parp-1 inhibitor ino-1001 facilitates hemodynamic stabilization without affecting DNA repair in porcine thoracic aortic cross-clamping-induced ischemia/reperfusion
Hauser, Balázs and Gröger, Michael and Ehrmann, Ulrich and Albicini, Maura and Brückner, Uwe Bernd and Schelzig, Hubert and Venkatesh, Balasubramanian and Li, Hongshan and Szabó, Csaba and Speit, Günter and others, Shock 25.6 (2006), 633–640 | Article

Graft derived cells with double nuclei in the penumbral region of experimental brain trauma
Horváth, Eszter M and Lacza, Zsombor and Csordás, Attila and Szabó, Csaba and Kollai, Márk and Busija, David W, Neuroscience letters 396.3 (2006), 182–186 | Article

Effects of 7-ketocholesterol on the activity of endothelial poly (ADP-ribose) polymerase and on endothelium-dependent relaxant function
Kiss, Levente and Chen, Min and Gero, Domokos and Módis, Katalin and Lacza, Zsombor and Szabó, Csaba, International journal of molecular medicine 18.6 (2006), 1113–1117 | Article

Mitochondria produce reactive nitrogen species via an arginine-independent pathway
Lacza, Zsombor and Kozlov, Andrey V and Pankotai, Eszter and Csordás, Attila and Wolf, Gerald and Redl, Heinz and Kollai, Márk and Szabó, Csaba and Busija, David W and Horn, Thomas FW, Free radical research 40.4 (2006), 369–378 | Article

Mitochondrial NO and reactive nitrogen species production: does mtNOS exist?
Lacza, Zsombor and Pankotai, Eszter and Csordás, Attila and Gero, Domokos and Kiss, Levente and Horváth, Eszter M and Kollai, Márk and Busija, David W and Szabó, Csaba, Nitric Oxide 14.2 (2006), 162–168 | Article

Short-term effects of glipizide (an adenosine triphosphate-sensitive potassium channel inhibitor) on cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep
Lange, Matthias and Szabo, Csaba and Van Aken, Hugo and Williams, William and Traber, Daniel L and Daudel, Fritz and Bröking, Katrin and Salzman, Andrew L and Bone, Hans-Georg and Westphal, Martin, Shock 26.5 (2006), 516–521 | Article

Altered calcium handling is an early sign of streptozotocin-induced diabetic cardiomyopathy
Ligeti, László and Szenczi, Orsolya and Prestia, Christina M and Szabó, Csaba and Horváth, Katalin and Marcsek, Zoltán L and Van Stiphout, Ruud GPM and Van Riel, Natal AW and Den Buijs, Jorn Op and Van der Vusse, Ger J and others, International journal of molecular medicine 17.6 (2006), 1035–1043 | Article

Activation of the poly (ADP-ribose) polymerase pathway in human heart failure
Molnár, Andrea and Tóth, Attila and Bagi, Zsolt and Papp, Zoltán and édes, István and Vaszily, Miklós and Galajda, Zoltán and Papp, Julius Gy and Varró, András and Szüts, Viktória and others, Molecular Medicine 12.7-8 (2006), 143 | Article

Effect of different dietary fat content and fat type on the growth and body composition of intensively reared pikeperch Sander lucioperca (L.)
Molnar, T and Szabo, A and Szabo, G and Szabo, C and Hancz, C, Aquaculture nutrition 12.3 (2006), 173–182 | Article

Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models
Obrosova, IG and Drel, VR and Kumagai, AK and Szabo, C and Pacher, P and Stevens, MJ, Diabetologia 49.10 (2006), 2525–2533 | Article

Beneficial effects of a novel ultrapotent poly (ADP-ribose) polymerase inhibitor in murine models of heart failure
Pacher, Pál and Liaudet, Lucas and Mabley, Jon G and Cziráki, Attila and Haskó, György and Szabó, Csaba, International journal of molecular medicine 17.2 (2006), 369–375 | Article

Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes
Pacher, Pál and Szabó, Csaba, Current opinion in pharmacology 6.2 (2006), 136–141 | Article

Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol
Pacher, PAL and Nivorozhkin, Alex and Szabó, Csaba, Pharmacological reviews 58.1 (2006), 87–114 | Article

Inhibition of experimental gingivitis in beagle dogs with topical mercaptoalkylguanidines
Paquette, David W and Rosenberg, Adam and Lohinai, Zsolt and Southan, Garry J and Williams, Ray C and Offenbacher, Steven and Szabó, Csaba, Journal of periodontology 77.3 (2006), 385–391 | Article

Indices of apoptosis activation after blood cardioplegia and cardiopulmonary bypass
Ramlawi, Basel and Feng, Jun and Mieno, Shigetoshi and Szabo, Csaba and Zsengeller, Zsuzsanna and Clements, Richard and Sodha, Neel and Boodhwani, Munir and Bianchi, Cesario and Sellke, Frank W, Circulation 114.1 suppl (2006), I–257 | Article

Potential role of poly (adenosine 5′-diphosphate-ribose) polymerase activation in the pathogenesis of myocardial contractile dysfunction associated with human septic shock
Soriano, Francisco G and Nogueira, Antonio C and Caldini, Elia G and Lins, Marcelo H and Teixeira, Ana C and Cappi, Sylas B and Lotufo, Paulo A and Bernik, Márcia MS and Zsengellér, Zsuzsanna and Chen, Min and others, Critical care medicine 34.4 (2006), 1073–1079 | Article

Contractile dysfunction in experimental cardiac allograft rejection: role of the poly (ADP-ribose) polymerase pathway
Szabó, Gábor and Bährle, Susanne and Stumpf, Nicole and Szabó, Csaba and Hagl, Siegfried, Transplant international 19.6 (2006), 506–513 | Article

Effects of inosine on reperfusion injury after heart transplantation
Szabó, Gábor and Stumpf, Nicole and Radovits, Tamás and Sonnenberg, Karin and Gerö, Domokos and Hagl, Siegfried and Szabó, Csaba and Bährle, Susanne, European journal of cardio-thoracic surgery 30.1 (2006), 96–102 | Article

Immunomodulatory effects of poly (ADP-ribose) polymerase inhibition contribute to improved cardiac function and survival during acute cardiac rejection
Szabó, Gábor and Bährle, Susanne and Sivanandam, Vijayshankar and Stumpf, Nicole and Gerö, Domokos and Berger, Irina and Beller, Carsten and Hagl, Siegfried and Szabó, Csaba and Dengler, Thomas J, The Journal of heart and lung transplantation 25.7 (2006), 794–804 | Article

Novel modulators of poly (ADP-ribose) polymerase
Szabo, Csaba and Pacher, Pal and Swanson, Raymond A, Trends in pharmacological sciences 27.12 (2006), 626–630 | Article

Poly (ADP-ribose) polymerase activation by reactive nitrogen species—relevance for the pathogenesis of inflammation
Szabó, Csaba, Nitric Oxide 14.2 (2006), 169–179 | Article

Poly (ADP-ribose) polymerase inhibitors ameliorate nephropathy of type 2 diabetic Leprdb/db mice
Szabó, Csaba and Biser, Alisha and Benkö, Rita and Böttinger, Erwin and Suszták, Katalin, Diabetes 55.11 (2006), 3004–3012 | Article

Activation of poly (ADP-ribose) polymerase by myocardial ischemia and coronary reperfusion in human circulating leukocytes
Tóth-Zsámboki, Emese and Horváth, Eszter and Vargova, Katarina and Pankotai, Eszter and Murthy, Kanneganti and Zsengellér, Zsuzsanna and Bárány, Tamás and Pék, Tamás and Fekete, Katalin and Kiss, Róbert Gábor and others, Molecular Medicine 12.9-10 (2006), 221 | Article

In vitro effect of the potent poly (ADP-ribose) polymerase (PARP) inhibitor INO-1001 alone and in combination with aspirin, eptifibatide, tirofiban, enoxaparin or alteplase on haemostatic parameters
Tóth, Orsolya and Szabó, Csaba and Kecskés, Marianna and Pótó, László and Nagy, ágnes and Losonczy, Hajna, Life sciences 79.4 (2006), 317–323 | Article

Gallotannin inhibits the expression of chemokines and inflammatory cytokines in A549 cells
Erdelyi, Katalin and Kiss, Andrea and Bakondi, Edina and Bai, Peter and Szabo, Csaba and Gergely, Pal and Erdodi, Ferenc and Virag, Laszlo, Molecular pharmacology (2005) | Article

Poly (ADP-Ribose) Polymerase Activation and Nitrosative Stress in the Development of Cardiovascular Disease in Diabetes in Diabetes and Cardiovascular Disease
Pacher, Pál and Szabó, Csaba ( Springer, 2005), 167–190 | Chapter

Pathophysiologic role of oxidative stress-induced poly (ADP-ribose) polymerase-1 activation: focus on cell death and transcriptional regulation.
Erdelyi, K and Bakondi, E and Gergely, P and Szabo, C and Virag, L, Cellular and molecular life sciences: CMLS 62.7-8 (2005), 751–759 | Article

Left ventricular pressure-volume relationship in a rat
Haskó, György and Kollai, Márk and Szabó, Csaba and Pacher, Pál and Mabley, Jon G and Liaudet, Lucas and Evgenov, Oleg V and Marton, Anita, Exp. Physiol 90.4 (2005), 627–634 | Article

The pathogenesis of diabetic complications: the role of DNA injury and poly (ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity
Kiss, Levente and Szabó, Csaba, Memorias do Instituto Oswaldo Cruz 100 (2005), 29–37 | Article

Pathways of cell death induced by peroxynitrite: Role of PARP. Relevance for circulatory shock and reperfusion injury in SHOCK
Szabo, C ( LIPPINCOTT WILLIAMS & WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA, 2005), 54–59 | Chapter

Beneficial effects of PJ34 and INO-1001, two novel water-soluble poly (ADP-ribose) polymerase inhibitors, on the consequences of traumatic brain injury in rat
Besson, Valérie C and Zsengellér, Zsuzsanna and Plotkine, Michel and Szabó, Csaba and Marchand-Verrecchia, Catherine, Brain research 1041.2 (2005), 149–156 | Article

Nebulized nitric oxide/nucleophile adduct reduces pulmonary vascular resistance in mechanically ventilated septicemic sheep
Bjertnaes, Lars J and McGuire, Roy and Jodoin, Jeffery and Salzman, Andrew L and Traber, Lillian D and Passerini, Daniel J and Smith, Daniel J and Szabo, Csaba and Traber, Daniel L, Critical care medicine 33.3 (2005), 616–622 | Article

Poly (adenosine diphosphate ribose) polymerase inhibition modulates spinal cord dysfunction after thoracoabdominal aortic ischemia-reperfusion
Casey, Patrick J and Black, James H and Szabo, Csaba and Frosch, Matthew and Albadawi, Hassan and Chen, Min and Cambria, Richard P and Watkins, Michael T, Journal of vascular surgery 41.1 (2005), 99–107 | Article

Poly (ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair–deficient malignant glioma xenograft
Cheng, C Lynn and Johnson, Stewart P and Keir, Stephen T and Quinn, Jennifer A and Ali-Osman, Francis and Szabo, Csaba and Li, Hongshan and Salzman, Andrew L and Dolan, M Eileen and Modrich, Paul and others, Molecular cancer therapeutics 4.9 (2005), 1364–1368 | Article

Excessive stimulation of poly (ADP-ribosyl) ation contributes to endothelial dysfunction in pre-eclampsia
Crocker, Ian P and Kenny, Louise C and Thornton, Wayne A and Szabo, Csaba and Baker, Philip N, British journal of pharmacology 144.6 (2005), 772–780 | Article

Poly (ADP) ribose polymerase inhibition improves rat cardiac allograft survival
Farivar, Alexander S and McCourtie, Anton S and MacKinnon-Patterson, Brendan C and Woolley, Steven M and Barnes, Andrew D and Chen, Min and Jagtap, Prakash and Szabó, Csaba and Salerno, Christopher T and Mulligan, Michael S, The Annals of thoracic surgery 80.3 (2005), 950–956 | Article

Free radical scavenging as a therapeutic strategy for bacteremia
Goldfarb, Roy D and Szabo, Csaba, Critical care medicine 33.5 (2005), 1163–1166 | Article

Clinical perspectives of PARP inhibitors
Graziani, Grazia and Szabó, Csaba, Pharmacological research 52.1 (2005), 109–118 | Article

Discovery of potent poly (ADP-ribose) polymerase-1 inhibitors from the modification of indeno [1, 2-c] isoquinolinone
Jagtap, Prakash G and Baloglu, Erkan and Southan, Garry J and Mabley, Jon G and Li, Hongshan and Zhou, Jing and van Duzer, John and Salzman, Andrew L and Szabó, Csaba, Journal of medicinal chemistry 48.16 (2005), 5100–5103 | Article

Facile and Convenient Syntheses of 6, 11-Dihydro-5 H-indeno [1, 2-c] isoquinolin-5-ones and 6, 11-Dihydro-5 H-indolo [3, 2-c] isoquinolin-5-one
Jagtap, Prakash G and Baloglu, Erkan and Southan, Garry and Williams, William and Roy, Aloka and Nivorozhkin, Alexander and Landrau, Nelson and Desisto, Kevin and Salzman, Andrew L and Szabó, Csaba, Organic letters 7.9 (2005), 1753–1756 | Article

Poly (ADP-ribose) polymerase and the therapeutic effects of its inhibitors
Jagtap, Prakash and Szabó, Csaba, Nature reviews Drug discovery 4.5 (2005), 421 | Article

Poly (Adenosine diphosphate-ribose) polymerase inhibition preserves erectile function in rats after cavernous nerve injury
Kendirci, Muammer and Zsengellér, Zsuzsanna and Bivalacqua, Trinity J and Gur, Serap and Usta, Mustafa F and Chen, Min and Szabó, Csaba and Hellstrom, Wayne JG, The Journal of urology 174.5 (2005), 2054–2059 | Article

Poly (adp-ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma
Komjati, Katalin and Besson, Valerie C and Szabo, Csaba, Current Drug Targets-CNS & Neurological Disorders 4.2 (2005), 179–194 | Article

The novel red-fluorescent probe DAR-4M measures reactive nitrogen species rather than NO
Lacza, Zsombor and Horváth, Eszter M and Pankotai, Eszter and Csordás, Attila and Kollai, Márk and Szabó, Csaba and Busija, David W, Journal of pharmacological and toxicological methods 52.3 (2005), 335–340 | Article

Effects Of Glipizide (an Atp-sensitive Potassium Channel Inhibitor) And Norepinephrine On Hemodynamics And Global Oxygen Transport In Endotoxemic Sheep.: 159-t
Lange, Matthias and Broeking, Katrin and Van Aken, Hugo and Daudel, Fritz and Bone, Hans-Georg and Westphal, Martin and Szabo, Csaba and Williams, William, Critical Care Medicine 33.12 (2005), A149 | Article

Low-dose poly (ADP-ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy
Li, Fei and Drel, Viktor R and Szabó, Csaba and Stevens, Martin J and Obrosova, Irina G, Diabetes 54.5 (2005), 1514–1522 | Article

Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly (ADP-ribose) polymerase activation
Mabley, Jon G and Horváth, Eszter M and Murthy, Kanneganti GK and Zsengellér, Zsuzsanna and Vaslin, Anne and Benkö, Rita and Kollai, Márk and Szabó, Csaba, Journal of Pharmacology and Experimental Therapeutics 315.2 (2005), 812–820 | Article

Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation
Mabley, Jon G and Pacher, Pál and Deb, Amitabha and Wallace, Rebecca and Elder, Rhoderick H and Szabó, Csaba, The FASEB journal 19.2 (2005), 290–292 | Article

Role of peroxynitrite anion in renal hypothermic preservation injury
Mangino, Martin J and Ametani, Mary S and Gilligan, Barbara J and Szabo, Csaba and Brounts, Lionel and Southard, James H, Transplantation 80.10 (2005), 1455–1460 | Article

Antibodies raised against N'-terminal Pseudomonas aeruginosa flagellin prevent mortality in lethal murine models of infection
Neville, Lewis F and Barnea, Yoav and Hammer-Munz, Orly and Gur, Eyal and Kuzmenko, Boris and Kahel-Raifer, Hamutal and Eren, Rachel and Elkeles, Adi and Murthy, Kanneganti GK and Szabó, Csaba and others, International journal of molecular medicine 16.1 (2005), 165–171 | Article

Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly (ADP-ribose) polymerase activation in tissue sites for diabetes complications
Obrosova, Irina G and Pacher, Pal and Szabó, Csaba and Zsengeller, Zsuzsanna and Hirooka, Hiroko and Stevens, Martin J and Yorek, Mark A, Diabetes 54.1 (2005), 234–242 | Article

Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst
Obrosova, Irina G and Mabley, Jon G and Zsengellér, Zsuzsanna and Charniauskaya, Tamara and Abatan, Omorodola I and Groves, John T and Szabó, Csaba, The FASEB journal 19.3 (2005), 401–403 | Article

beta-adrenergic activation reveals impaired cardiac calcium handling at early stage of diabetes
op den Buijs, Jorn and Miklós, Zsuzsanna and van Riel, Natal AW and Prestia, Christina M and Szenczi, Orsolya and Tóth, András and Van der Vusse, Ger J and Szabó, Csaba and Ligeti, László and Ivanics, Tamás, Life sciences 76.10 (2005), 1083–1098 | Article

Nitrosative stress and pharmacological modulation of heart failure
Pacher, Pal and Schulz, Richard and Liaudet, Lucas and Szabó, Csaba, Trends in Pharmacological Sciences 26.6 (2005), 302–310 | Article

Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies
Pacher, Pál and Obrosova, Irina G and Mabley, Jon G and Szabó, Csaba, Current medicinal chemistry 12.3 (2005), 267–275 | Article

Role of poly (ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme
Pacher, Pál and Szabó, Csaba, Antioxidants & redox signaling 7.11-12 (2005), 1568–1580 | Article

INFLAMMATION AND IMMUNOPHARMACOLOGY-Protective Mechanisms of a Metalloporphyrinic Peroxynitrite Decomposition Catalyst, WW85, in Rat Cardiac Transplants
Pieper, Galen M and Nilakantan, Vani and Chen, Min and Zhou, Jing and Khanna, Ashwani K and Henderson Jr, James D and Johnson, Christopher P and Roza, Allan M and Szabo, Csaba, Journal of Pharmacology and Experimental Therapeutics 314.1 (2005), 53–60 | Article

Protective mechanisms of a metalloporphyrinic peroxynitrite decomposition catalyst, WW85, in rat cardiac transplants
Pieper, Galen M and Nilakantan, Vani and Chen, Min and Zhou, Jing and Khanna, Ashwani K and Henderson, James D and Johnson, Christopher P and Roza, Allan M and Szabó, Csaba, Journal of Pharmacology and Experimental Therapeutics 314.1 (2005), 53–60 | Article

Na+, K+-ATPase activity is inhibited in cultured intestinal epithelial cells by endotoxin or nitric oxide
Suzuki, Yoshihiko and Lu, Qi and Xu, Da-Zhong and Szabó, Csaba and Haskó, György and Deitch, Edwin A, International journal of molecular medicine 15.5 (2005), 871–877 | Article

Cardioprotective effects of poly (ADP-ribose) polymerase inhibition
Szabó, Csaba, Pharmacological research 52.1 (2005), 34–43 | Article

Mechanisms of cell necrosis
Szabó, Csaba, Critical care medicine 33.12 (2005), S530–S534 | Article

Pharmacological inhibition of poly (ADP-ribose) polymerase in cardiovascular disorders: future directions
Szabo, Csaba, Current vascular pharmacology 3.3 (2005), 301–303 | Article

Poly (ADP-ribose) polymerase inhibition attenuates biventricular reperfusion injury after orthotopic heart transplantation
Szabó, Gábor and Soós, Pál and Heger, Ulrike and Flechtenmacher, Christa and Bährle, Susanne and Zsengellér, Zsuzsanna and Szabó, Csaba and Hagl, Siegfried, European journal of cardio-thoracic surgery 27.2 (2005), 226–234 | Article

Roles of poly (ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications
Szabó, Csaba, Pharmacological research 52.1 (2005), 60–71 | Article

Poly (ADP-ribose) polymerase regulates myocardial calcium handling in doxorubicin-induced heart failure
Szenczi, Orsolya and Kemecsei, Péter and Holthuijsen, Max FJ and van Riel, Natal AW and van der Vusse, Ger J and Pacher, Pál and Szabó, Csaba and Kollai, Márk and Ligeti, László and Ivanics, Tamás, Biochemical pharmacology 69.5 (2005), 725–732 | Article

Poly (ADP-Ribose) polymerase promotes cardiac remodeling, contractile failure, and translocation of apoptosis-inducing factor in a murine experimental model of aortic banding and heart failure
Xiao, Chun-Yang and Chen, Min and Zsengellér, Zsuzsanna and Li, Hongshan and Kiss, Levente and Kollai, Márk and Szabó, Csaba, Journal of Pharmacology and Experimental Therapeutics 312.3 (2005), 891–898 | Article

The therapeutic effects of PJ34, a selective inhibitor of poly (ADP-ribose) polymerase, in experimental allergic encephalomyelitis are associated with immunomodulation
Scott, Gwen S and Kean, Rhonda B and Mikheeva, Tatiana and Fabis, Marzena J and Mabley, Jon G and Szabó, Csaba and Hooper, D Craig, Journal of Pharmacology and Experimental Therapeutics 310 (2004), 1053–1061 | Article

Matrix metalloproteinase activation is an early event in doxorubicin-induced cardiotoxicity
Bai, Péter and Mabley, Jon G and Liaudet, Lucas and Virág, László and Szabó, Csaba and Pacher, Pál, Oncology reports 11.2 (2004), 505–508 | Article

Cytoprotective effect of gallotannin in oxidatively stressed HaCaT keratinocytes: the role of poly (ADP-ribose) metabolism
Bakondi, Edina and Bai, Péter and Erdélyi, Katalin and Szabó, Csaba and Gergely, Pál and Virág, László, Experimental dermatology 13.3 (2004), 170–178 | Article

Restoration of the endothelial function in the aortic rings of apolipoprotein E deficient mice by pharmacological inhibition of the nuclear enzyme poly (ADP-ribose) polymerase
Benkö, Rita and Pacher, Pál and Vaslin, Anne and Kollai, Márk and Szabó, Csaba, Life sciences 75.10 (2004), 1255–1261 | Article

Radiosensitization of human and rodent cell lines by INO-1001, a novel inhibitor of poly (ADP-ribose) polymerase
Brock, William A and Milas, Luka and Bergh, Sherry and Lo, Ruth and Szabó, Csaba and Mason, Kathy A, Cancer letters 205.2 (2004), 155–160 | Article

Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: potential role of poly (ADP-ribose) polymerase-1
Chen, Min and Zsengellér, Zsuzsanna and Xiao, Chun-Yang and Szabó, Csaba, Cardiovascular research 63.4 (2004), 682–688 | Article

Intratracheal poly (ADP) ribose synthetase inhibition ameliorates lung ischemia reperfusion injury
Farivar, Alexander S and Woolley, Steven M and Fraga, Charles H and Thomas, Robert and Salzman, Andrew L and Szabo, Csaba and Mulligan, Michael S, The Annals of thoracic surgery 77.6 (2004), 1938–1943 | Article

Poly (ADP) ribose synthetase inhibition reduces obliterative airway disease in rat tracheal allografts
Farivar, Alexander S and Woolley, Steven M and Naidu, Babu V and Fraga, Charles H and Byrne, Karen and Thomas, Robert and Salzman, Andrew L and Szabo, Csaba S and Mulligan, Michael S, The Journal of heart and lung transplantation 23.8 (2004), 993–1002 | Article

Immunomodulatory and neuroprotective effects of inosine
Haskó, György and Sitkovsky, Michail V and Szabó, Csaba, Trends in pharmacological sciences 25.3 (2004), 152–157 | Article

2-(N-Acyl) and 2-N-acyl-N 6-substituted analogues of adenosine and their affinity at the human adenosine receptors
Jagtap, Prakash G and Chen, Zhiyu and Szabó, Csaba and Klotz, Karl-Norbert, Bioorganic & medicinal chemistry letters 14.6 (2004), 1495–1498 | Article

The discovery and synthesis of novel adenosine substituted 2, 3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly (ADP-ribose) polymerase-1 (PARP-1)
Jagtap, Prakash G and Southan, Garry J and Baloglu, Erkan and Ram, Siya and Mabley, Jon G and Marton, Anita and Salzman, Andrew and Szabo, Csaba, Bioorganic & medicinal chemistry letters 14.1 (2004), 81–85 | Article

Poly (ADP-ribose) polymerase inhibition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke
Komjáti, Katalin and Mabley, John G and Virág, László and Southan, Garry J and Salzman, Andrew L and Szabó, Csaba, International journal of molecular medicine 13.3 (2004), 373–382 | Article

Lack of mitochondrial nitric oxide production in the mouse brain
Lacza, Zsombor and Horn, Thomas FW and Snipes, James A and Zhang, Jie and Roychowdhury, Sanjoy and Horváth, Eszter M and Figueroa, Jorge P and Kollai, Márk and Szabó, Csaba and Busija, David W, Journal of neurochemistry 90.4 (2004), 942–951 | Article

Evaluation of orally active poly (ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy
Li, F and Szabo, C and Pacher, P and Southan, GJ and Abatan, OI and Charniauskaya, T and Stevens, Martin J and Obrosova, IG, Diabetologia 47.4 (2004), 710–717 | Article

The combined inducible nitric oxide synthase inhibitor and free radical scavenger guanidinoethyldisulfide prevents multiple low-dose streptozotocin-induced diabetes in vivo and interleukin-1beta-induced suppression of islet insulin secretion in vitro
Mabley, Jon G and Southan, Gary J and Salzman, Andrew L and Szabó, Csaba, Pancreas 28.2 (2004), e39–e44 | Article

Suppression of intestinal polyposis in Apc min/+ mice by targeting the nitric oxide or poly (ADP-ribose) pathways
Mabley, Jon G and Pacher, Pál and Bai, Peter and Wallace, Rebecca and Goonesekera, Sunali and Virag, Laszlo and Southan, Garry J and Szabó, Csaba, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 548.1 (2004), 107–116 | Article

Poly (ADP-ribose) polymerase and renal hypothermic preservation injury
Mangino, Martin J and Ametani, Mary and Szabó, Csaba and Southard, James H, American Journal of Physiology-Renal Physiology 286.5 (2004), F838–F847 | Article

The ATP-sensitive potassium-channel inhibitor glibenclamide improves outcome in an ovine model of hemorrhagic shock
Maybauer, Dirk M and Salsbury, John R and Westphal, Martin and Maybauer, Marc O and Salzman, Andrew L and Szabó, Csaba and Westphal-Varghese, Beena B and Traber, Lillian D and Traber, Daniel L, Shock 22.4 (2004), 387–391 | Article

Inhibition of poly (ADP-ribose) polymerase attenuates acute lung injury in an ovine model of sepsis
Murakami, Kazunori and Enkhbaatar, Perenlei and Shimoda, Katsumi and Cox, Robert A and Burke, Ann S and Hawkins, Hal K and Traber, Lillian D and Schmalstieg, Frank C and Salzman, Andrew L and Mabley, Jon G and others, Shock 21.2 (2004), 126–133 | Article

Activation of poly (ADP-ribose) polymerase in circulating leukocytes during myocardial infarction
Murthy, Kanneganti GK and Xiao, Chun-Yang and Mabley, Jon G and Chen, Min and Szabo, Csaba, Shock 21.3 (2004), 230–234 | Article

Cytokines stimulate expression of inducible nitric oxide synthase in DLD-1 human adenocarcinoma cells by activating poly (A) polymerase
Murthy, KGK and Szabo, C and Salzman, AL, Inflammation Research 53.11 (2004), 604–608 | Article

Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro
Murthy, Kanneganti GK and Deb, Amitabha and Goonesekera, Sunali and Szabó, Csaba and Salzman, Andrew L, Journal of Biological Chemistry 279.7 (2004), 5667–5675 | Article

Disruption of the actin cytoskeleton results in nuclear factor-kappaB activation and inflammatory mediator production in cultured human intestinal epithelial cells
Németh, Zoltán H and Deitch, Edwin A and Davidson, Marson T and Szabó, Csaba and Vizi, E Sylvester and Haskó, György, Journal of cellular physiology 200.1 (2004), 71–81 | Article

Proteasome inhibitors induce inhibitory kB (IkB) kinase activation, IkBa degradation, and nuclear factor kB activation in HT-29 cells
Nemeth, Zoltan H and Wong, Hector R and Odoms, Kelli and Deitch, Edwin A and Szabo, Csaba and Vizi, E Sylvester and Hasko, Gyorgy, Molecular Pharmacology 65.2 (2004), 342–349 | Article

Proteasome inhibitors induce inhibitory kappaB (IkappaB) kinase activation, IkappaBalpha degradation, and nuclear factor kappaB activation in HT-29 cells
Németh, Zoltán H and Wong, Hector R and Odoms, Kelli and Deitch, Edwin A and Szabó, Csaba and Vizi, E Sylvester and Haskó, György, Molecular pharmacology 65.2 (2004), 342–349 | Article

Poly (ADP-ribose) polymerase inhibitors counteract diabetes-and hypoxia-induced retinal vascular endothelial growth factor overexpression
Obrosova, Irina G and Minchenko, Alexander G and Frank, Robert N and Seigel, Gail M and Zsengeller, Zsuzsanna and Pacher, Pál and Stevens, Martin J and Szabó, Csaba, International journal of molecular medicine 14.1 (2004), 55–64 | Article

Role of poly (ADP-ribose) polymerase activation in diabetic neuropathy
Obrosova, Irina G and Li, Fei and Abatan, Omorodola I and Forsell, Mark A and Komjáti, Katalin and Pacher, Pal and Szabo, Csaba and Stevens, Martin J, Diabetes 53.3 (2004), 711–720 | Article

A new, potent poly (ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging
Pacher, Pál and Vaslin, Anne and Benkö, Rita and Mabley, Jon G and Liaudet, Lucas and Haskó, György and Marton, Anita and Bátkai, Sándor and Kollai, Márk and Szabó, Csaba, Journal of Pharmacology and Experimental Therapeutics 311.2 (2004), 485–491 | Article

Intermittent high glucose enhances ICAM-1, VCAM-1, E-selectin and interleukin-6 expression in human umbilical endothelial cells in culture: the role of poly (ADP-ribose) polymerase
Piconi, L and Quagliaro, L and Da Ros, R and Assaloni, R and Giugliano, D and Esposito, K and Szabo, C and Ceriello, Antonio, Journal of Thrombosis and Haemostasis 2.8 (2004), 1453–1459 | Article

INFLAMMATION AND IMMUNOPHARMACOLOGY-The Therapeutic Effects of PJ34 (N-(6-Oxo-5, 6-dihydrophenanthridin-2-yl)-N, N-dimethylacetamide. HCl), a Selective Inhibitor of Poly (ADP-Ribose) Polymerase, in
Scott, Gwen S and Kean, Rhonda B and Mikheeva, Tatiana and Fabis, Marzena J and Mabley, Jon G and Szabo, Csaba and Hooper, D Craig, Journal of Pharmacology and Experimental Therapeutics 310.3 (2004), 1053–1061 | Article

Poly (ADP-ribose) polymerase activity contributes to peroxynitrite-induced spinal cord neuronal cell death in vitro
Scott, Gwen S and Szabó, Csaba and Hooper, D Craig, Journal of neurotrauma 21.9 (2004), 1255–1263 | Article

The therapeutic effects of PJ34 [N-(6-oxo-5, 6-dihydrophenanthridin-2-yl)-N, N-dimethylacetamide. HCl], a selective inhibitor of poly (ADP-ribose) polymerase, in experimental allergic encephalomyelitis are associated with immunomodulation
Scott, Gwen S and Kean, Rhonda B and Mikheeva, Tatiana and Fabis, Marzena J and Mabley, Jon G and Szabo, Csaba and Hooper, D Craig, Journal of Pharmacology and Experimental Therapeutics 310.3 (2004), 1053–1061 | Article

Peroxynitrite decomposition catalyst, FP15, and poly (ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats
Sugawara, R and Hikichi, T and Kitaya, N and Mori, F and Nagaoka, T and Yoshida, A and Szabo, C, Current eye research 29.1 (2004), 11–16 | Article

Angiotensin II–mediated endothelial dysfunction: role of poly (ADP-ribose) polymerase activation
Szabó, Csaba and Pacher, Pál and Zsengellér, Zsuzsanna and Vaslin, Anne and Komjáti, Katalin and Benkö, Rita and Chen, Min and Mabley, Jon G and Kollai, Márk, Molecular Medicine 10.1-6 (2004), 28 | Article

INO-1001 a novel poly (ADP-ribose) polymerase (PARP) inhibitor improves cardiac and pulmonary function after crystalloid cardioplegia and extracorporal circulation
Szabó, Gábor and Soós, Pál and Mandera, Susanne and Heger, Ulrike and Flechtenmacher, Christa and Bährle, Susanne and Seres, Leila and Cziráki, Attila and Gries, Andre and Zsengellér, Zsuszanna and others, Shock 21.5 (2004), 426–432 | Article

Mesenteric injury after cardiopulmonary bypass: role of poly (adenosine 5′-diphosphate-ribose) polymerase
Szabó, Gábor and Soós, Pál and Mandera, Susanne and Heger, Ulrike and Flechtenmacher, Christa and Seres, Leila and Zsengellér, Zsuzsanna and Sack, Falk-Udo and Szabó, Csaba and Hagl, Siegfried, Critical care medicine 32.12 (2004), 2392–2397 | Article

Poly-ADP-ribose polymerase inhibition reduces mesenteric injury after cardiopulmonary bypass
Szabó, Gábor and Seres, L and Soos, P and Flechtenmacher, C and Zsengeller, Z and Sack, F-U and Szabó, C and Hagl, S, The Thoracic and cardiovascular surgeon 52.06 (2004), 338–343 | Article

Poly (ADP-ribose) polymerase activation in the reperfused myocardium
Szabó, Gábor and Liaudet, Lucas and Hagl, Siegfried and Szabó, Csaba, Cardiovascular research 61.3 (2004), 471–480 | Article

Role of poly (ADP-ribose) polymerase activation in the pathogenesis of cardiopulmonary dysfunction in a canine model of cardiopulmonary bypass
Szabó, Gábor and Soós, Pál and Bährle, Susanne and Zsengellér, Zsuzsanna and Flechtenmacher, Christa and Hagl, Siegfried and Szabó, Csaba, European journal of cardio-thoracic surgery 25.5 (2004), 825–832 | Article

Effects of poly (ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma
Virág, László and Bai, Peter and Bak, István and Pacher, Pal and Mabley, Jon and Liaudet, Lucas and Bakondi, Edina and Gergely, Pal and Kollai, Mark and Szabo, Csaba, Medical Science Monitor 10.3 (2004), BR77–BR83 | Article

Role of Poly (ADP) ribose synthetase in lung ischemia—reperfusion injury
Woolley, Steven M and Farivar, Alexander S and Naidu, Babu V and Salzman, Andrew and Szabo, Csaba and Thomas, Robert and Fraga, Charles and Mulligan, Michael S, The Journal of heart and lung transplantation 23.11 (2004), 1290–1296 | Article

Poly (ADP-ribose) polymerase contributes to the development of myocardial infarction in diabetic rats and regulates the nuclear translocation of apoptosis-inducing factor
Xiao, Chun-Yang and Chen, Min and Zsengellér, Zsuzsanna and Szabó, Csaba, Journal of Pharmacology and Experimental Therapeutics 310.2 (2004), 498–504 | Article

Poly (ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB
Zheng, Ling and Szabó, Csaba and Kern, Timothy S, Diabetes 53.11 (2004), 2960–2967 | Article

Nicotinamide: a jack of all trades (but master of none?)
Szabó, Csaba, (2003) | Misc

Medicinal Chemistry and Therapeutic Applications of the Gasotransmitters NO, CO, and H 2 S and their Prodrugs
Szabo, Csaba, Burger's Medicinal Chemistry and Drug Discovery (2003), 265–368 | Article

Multiple pathways of peroxynitrite cytotoxicity
Szabo, Csaba, Toxicology letters 140 (2003), 105–112 | Article

Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention
Virág, Lászlo and Szabo, Eva and Gergely, Pál and Szabo, Csaba, Toxicology letters 140 (2003), 113–124 | Article

Role of intracellular calcium mobilization and cell-density-dependent signaling in oxidative-stress-induced cytotoxicity in HaCaT keratinocytes
Bakondi, Edina and Gönczi, Mónika and Szabó, éva and Bai, Péter and Pacher, Pál and Gergely, Pál and Kovács, László and Hunyadi, János and Szabó, Csaba and Csernoch, László and others, Journal of investigative dermatology 121.1 (2003), 88–95 | Article

Inhibition of GAPDH activity by poly (ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells
Du, Xueliang and Matsumura, Takeshi and Edelstein, Diane and Rossetti, Luciano and Zsengellér, Zsuzsanna and Szabó, Csaba and Brownlee, Michael, The Journal of clinical investigation 112.7 (2003), 1049–1057 | Article

Intra-mitochondrial poly (ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress
Du, Lina and Zhang, Xiaopeng and Han, Yong Y and Burke, Nancy A and Kochanek, Patrick M and Watkins, Simon C and Graham, Steven H and Carcillo, Joseph A and Szabó, Csaba and Clark, Robert SB, Journal of Biological Chemistry 278.20 (2003), 18426–18433 | Article

Parenteral administration of glipizide sodium salt, an inhibitor of adenosine triphosphate-sensitive potassium channels, prolongs short-term survival after severe controlled hemorrhage in rats
Evgenov, Oleg V and Pacher, Pál and Williams, William and Evgenov, Natalia V and Mabley, Jon G and Cicila, James and Sikó, Zsombor B and Salzman, Andrew L and Szabó, Csaba, Critical care medicine 31.10 (2003), 2429–2436 | Article

Integrin-mediated suppression of endotoxin-induced DNA damage in lung endothelial cells is sensitive to poly (ADP-ribose) polymerase-1 gene deletion
Huang, Hong and McINTOSH, JANE L and Fang, Lanyan and Szabo, Csaba and Hoyt, Dale G, International journal of molecular medicine 12.4 (2003), 533–540 | Article

Systemic and hepatosplanchnic hemodynamic and metabolic effects of the PARP inhibitor PJ34 during hyperdynamic porcine endotoxemia
Iványi, Zsolt and Hauser, Balázs and Pittner, Antje and Asfar, Pierre and Vassilev, Damian and Nalos, Marek and Altherr, Jürgen and Brückner, Uwe Bernd and Szabó, Csaba and Radermacher, Peter and others, Shock 19.5 (2003), 415–421 | Article

Poly (ADP-ribose) polymerase inhibition improves postischemic myocardial function after cardioplegia-cardiopulmonary bypass
Khan, Tanveer A and Ruel, Marc and Bianchi, Cesario and Voisine, Pierre and Komjáti, Katalin and Szabo, Csaba and Sellke, Frank W, Journal of the American College of Surgeons 197.2 (2003), 270–277 | Article

Heart mitochondria contain functional ATP-dependent K+ channels
Lacza, Zsombor and Snipes, James A and Miller, Allison W and Szabó, Csaba and Grover, Gary and Busija, David W, Journal of molecular and cellular cardiology 35.11 (2003), 1339–1347 | Article

Investigation of the subunit composition and the pharmacology of the mitochondrial ATP-dependent K+ channel in the brain
Lacza, Zsombor and Snipes, James A and Kis, Béla and Szabó, Csaba and Grover, Gary and Busija, David W, Brain research 994.1 (2003), 27–36 | Article

Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS
Lacza, Zsombor and Snipes, James A and Zhang, Jie and Horváth, Eszter M and Figueroa, Jorge P and Szabó, Csaba and Busija, David W, Free Radical Biology and Medicine 35.10 (2003), 1217–1228 | Article

PARP inhibition improves the effectiveness of neural stem cell transplantation in experimental brain trauma
Lacza, Zsombor and Horváth, Eszter M and Komjáti, Katalin and Hortobágyi, Tibor and Szabó, Csaba and Busija, David W, International journal of molecular medicine 12.2 (2003), 153–159 | Article

Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis
Liaudet, Lucas and Szabo, Csaba and Evgenov, Oleg V and Murthy, Kanneganti G and Pacher, Pál and Virág, Lászlo and Mabley, Jon G and Marton, Anita and Soriano, Francisco G and Kirov, Mikhail Y and others, Shock 19.2 (2003), 131–137 | Article

Oxidative stress and regional ischemia-reperfusion injury: the peroxynitrite–poly (ADP-ribose) polymerase connection
Liaudet, Lucas and Szabo, Gabor and Szabo, Csaba, Coronary artery disease 14.2 (2003), 115–122 | Article

Role of the activation of the nuclear enzyme poly (ADP-ribose) polymerase in the pathogenesis of periodontitis
Lohinai, Z and Mabley, JG and Feher, E and Marton, A and Komjati, K and Szabo, C, Journal of dental research 82.12 (2003), 987–992 | Article

The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide, is protective in two murine models of colitis
Mabley, Jon and Soriano, Francisco and Pacher, Pál and Haskó, György and Marton, Anita and Wallace, Rebecca and Salzman, Andrew and Szabó, Csaba, European journal of pharmacology 466.3 (2003), 323–329 | Article

Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes
Mabley, Jon G and Rabinovitch, Alex and Suarez-Pinzon, Wilma and Haskó, György and Pacher, Pál and Power, Robert and Southan, Gary and Salzman, Andrew and Szabó, Csaba, Molecular Medicine 9.3-4 (2003), 96 | Article

Inosine reduces inflammation and improves survival in a murine model of colitis
Mabley, Jon G and Pacher, Pal and Liaudet, Lucas and Soriano, Francisco G and Hasko, Gyorgy and Marton, Anita and Szabo, Csaba and Salzman, Andrew L, American Journal of Physiology-Gastrointestinal and Liver Physiology 284.1 (2003), G138–G144 | Article

Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly (ADP-ribose) polymerase activation
Minchenko, Alexander G and Stevens, Martin J and White, Lauren and Abatan, Omorodola I and Komjáti, Katalin and Pacher, Pal and Szabó, Csaba and Obrosova, Irina G, The FASEB Journal 17.11 (2003), 1514–1516 | Article

Critical role of reactive nitrogen species in lung ischemia–reperfusion injury
Naidu, Babu V and Fraga, Charles and Salzman, Andrew L and Szabo, Csaba and Verrier, Edward D and Mulligan, Michael S, The Journal of heart and lung transplantation 22.7 (2003), 784–793 | Article

Enhanced peroxynitrite decomposition protects against experimental obliterative bronchiolitis
Naidu, Babu V and Farivar, Alexander S and Woolley, Steven M and Fraga, Charles and Salzman, Andrew L and Szabo, Csaba and Groves, John T and Mulligan, Michael S, Experimental and molecular pathology 75.1 (2003), 12–17 | Article

cDNA microarray analysis reveals a nuclear factor-kappaB-independent regulation of macrophage function by adenosine
Néemeth, Zoltán H and Leibovich, S Joseph and Deitch, Edwin A and Vizi, E Sylvester and Szabó, Csaba and Haskó, György, Journal of Pharmacology and Experimental Therapeutics 306.3 (2003), 1042–1049 | Article

Adenosine stimulates CREB activation in macrophages via a p38 MAPK-mediated mechanism
Németh, Zoltán H and Leibovich, S Joseph and Deitch, Edwin A and Sperlágh, Beáta and Virág, László and Vizi, E Sylvester and Szabó, Csaba and Haskó, György, Biochemical and biophysical research communications 312.4 (2003), 883–888 | Article

Pyrrolidinedithiocarbamate inhibits NF-kappaB activation and IL-8 production in intestinal epithelial cells
Németh, Zoltán H and Deitch, Edwin A and Szabó, Csaba and Haskó, György, Immunology letters 85.1 (2003), 41–46 | Article

Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction
Pacher, Pál and Liaudet, Lucas and Bai, Péter and Mabley, Jon G and Kaminski, Pawel M and Virág, László and Deb, Amitabha and Szabó, éva and Ungvári, Zoltán and Wolin, Michael S and others, Circulation 107.6 (2003), 896–904 | Article

Topical administration of a novel nitric oxide donor, linear polyethylenimine-nitric oxide/nucleophile adduct (DS1), selectively increases vaginal blood flow in anesthetized rats
Pacher, P and Mabley, JG and Liaudet, L and Evgenov, OV and Southan, GJ and Abdelkarim, GE and Szabo, C and Salzman, AL, International journal of impotence research 15.6 (2003), 461 | Article

A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14-3-3gamma
Satchell, Margaret A and Zhang, Xiaopeng and Kochanek, Patrick M and Dixon, C Edward and Jenkins, Larry W and Melick, John and Szabó, Csaba and Clark, Robert SB, Journal of neurochemistry 85.3 (2003), 697–708 | Article

Peroxynitrite-induced oligodendrocyte toxicity is not dependent on poly (ADP-ribose) polymerase activation
Scott, Gwen S and Virág, Laszlo and Szabó, Csaba and Hooper, D Craig, Glia 41.2 (2003), 105–116 | Article

Effect of poly (ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep
Shimoda, Katsumi and Murakami, Kazunori and Enkhbaatar, Perenlei and Traber, Lillian D and Cox, Robert A and Hawkins, Hal K and Schmalstieg, Frank C and Komjáti, Katalin and Mabley, Jon G and Szabó, Csaba and others, American Journal of Physiology-Lung Cellular and Molecular Physiology 285.1 (2003), L240–L249 | Article

Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes
Suarez-Pinzon, Wilma L and Mabley, Jon G and Power, Robert and Szabo, Csaba and Rabinovitch, Alex, Diabetes 52.7 (2003), 1683–1688 | Article

Poly-ADP-ribose polymerase inhibition protects against myocardial and endothelial reperfusion injury after hypothermic cardiac arrest
Szabó, Gábor and Buhmann, Volker and Andrási, Terézia and Stumpf, Nicole and Bährle, Susanne and Kékesi, Violetta and Hagl, Siegfried and Szabó, Csaba and Juhász-Nagy, Alexander, The Journal of thoracic and cardiovascular surgery 126.3 (2003), 651–658 | Article

Role of flagellin in the pathogenesis of shock and acute respiratory distress syndrome: therapeutic opportunities
Szabó, Csaba, Critical care medicine 31.1 (2003), S39–S45 | Article

Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock
Veres, Balazs and Gallyas Jr, Ferenc and Varbiro, Gabor and Berente, Zoltan and Osz, Erzsebet and Szekeres, Gyorgy and Szabo, Csaba and Sumegi, Balazs, Biochemical pharmacology 65.8 (2003), 1373–1382 | Article

Identification of protein motifs and the role of particular amino acids in biological activity of flagellin as an inducer of proinflammatory response in human cells in FASEB JOURNAL
Murthy, KGK and Deb, A and Goonesekera, S and Szabo, C and Salzman, AL ( FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA, 2003), A965–A965 | Chapter

A novel xanthine oxidase inhibitor, AN-01-24, protects against development of colitis in mice in FASEB JOURNAL
Nivorozhkin, A and Mabley, JG and Pacher, P and Southan, GJ and Szabó, C and Salzman, AL ( FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA, 2003), A265–A265 | Chapter

A novel class of potent non-purine based xanthine oxidase inhibitors: antihyperuricemic and hepatoprotective effects in FASEB JOURNAL
Nivorozhkin, A and Mabley, JG and Pacher, P and Li, HS and Salzman, AL and Szabó, C and Southan, GJ ( FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA, 2003), A253–A253 | Chapter

Detection of peroxynitrite-induced protein and DNA modifications in Oxidants and Antioxidants
Lorch, Scott and Lightfoot, Richard and Ohshima, Hiroshi and Virág, László and Chen, Qiping and Hertkorn, Caryn and Weiss, Marie and Souza, Jose and Ischiropoulos, Harry and Yermilov, Vladimir and others ( Springer, 2002), 247–275 | Chapter

Detection of certain peroxynitrite-induced DNA modifications in Oxidative Stress Biomarkers and Antioxidant Protocols
Ohshima, Hiroshi and Virág, László and Souza, Jose and Yermilov, Vladimir and Pignatelli, Brigitte and Masuda, Mitsuharu and Szabó, Csaba ( Springer, 2002), 77–88 | Chapter

The flagellin-TLR5 axis: therapeutic opportunities
Liaudet, Lucas and Deb, Amitabha and Pacher, Pál and Mabley, Jon G and Murthy, KG and Salzman, Andrew L and Szabó, Csaba, Drug News Perspect 15.7 (2002), 397–409 | Article

Detection of Certain Peroxynitrite-Induced
Ohshima, Hiroshi and Virág, László and Souza, Jose and Yermilov, Vladimir and Pignatelli, Brigitte and Masuda, Mitsuharu and Szabó, Csaba, Oxidative Stress Biomarkers and Antioxidant Protocols 186 (2002), 77 | Article

PARP as a drug target for the therapy of diabetic cardiovascular dysfunction
Szabó, Csaba, Drug News Perspect 15.4 (2002), 197–205 | Article

Detection of poly (ADP-ribose) polymerase activation in oxidatively stressed cells and tissues using biotinylated NAD substrate
Bakondi, Edina and Bai, Péter and Szabó, éva and Hunyadi, János and Gergely, Pál and Szabó, Csaba and Virág, László, Journal of Histochemistry & Cytochemistry 50.1 (2002), 91–98 | Article

A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs
Bianchi, Cesario and Wakiyama, Hidetaka and Faro, Renato and Khan, Tanveer and McCully, James D and Levitsky, Sidney and Szabo, Csaba and Sellke, Frank W, The Annals of thoracic surgery 74.4 (2002), 1201–1207 | Article

Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor
Faro, Renato and Toyoda, Yoshiya and McCully, James D and Jagtap, Prakash and Szabo, Eva and Virag, Laszlo and Bianchi, Cesario and Levitsky, Sidney and Szabo, Csaba and Sellke, Frank W, The Annals of thoracic surgery 73.2 (2002), 575–581 | Article

Protective effect of a novel, potent inhibitor of poly (adenosine 5′-diphosphate-ribose) synthetase in a porcine model of severe bacterial sepsis
Goldfarb, Roy D and Marton, Anita and Szabó, éva and Virág, László and Salzman, Andrew L and Glock, Dana and Akhter, Imran and McCarthy, Robert and Parrillo, Joseph E and Szabó, Csaba, Critical care medicine 30.5 (2002), 974–980 | Article

Adenosine: a potential mediator of immunosuppression in multiple organ failure
Haskó, György and Deitch, Edwin A and Szabó, Csaba and Németh, Zoltán H and Vizi, E Sylvester, Current opinion in pharmacology 2.4 (2002), 440–444 | Article

Dopamine suppresses IL-12 p40 production by lipopolysaccharide-stimulated macrophages via a beta-adrenoceptor-mediated mechanism
Haskó, György and Szabó, Csaba and Németh, Zoltán H and Deitch, Edwin A, Journal of neuroimmunology 122.1-2 (2002), 34–39 | Article

Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages
Haskó, György and Deitch, Edwin A and Németh, Zoltán H and Kuhel, David G and Szabó, Csaba, Journal of Pharmacology and Experimental Therapeutics 301.1 (2002), 103–110 | Article

Poly (ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation.
Haskó, György and Mabley, Jon G and Németh, Zoltán H and Pacher, Pál and Deitch, Edwin A and Szabó, Csaba, Molecular Medicine 8.5 (2002), 283 | Article

Novel phenanthridinone inhibitors of poly (adenosine 5′-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents
Jagtap, Prakash and Soriano, Francisco Garcia and Virág, László and Liaudet, Lucas and Mabley, Jon and Szabó, éva and Haskó, György and Marton, Anita and Lorigados, Clara Batista and Gallyas, Ferenc and others, Critical care medicine 30.5 (2002), 1071–1082 | Article

Aerosolized linear polyethylenimine-nitric oxide/nucleophile adduct attenuates endotoxin-induced lung injury in sheep
Kirov, Mikhail Y and Evgenov, Oleg V and Kuklin, Vladimir N and Virág, László and Pacher, Pál and Southan, Garry J and Salzman, Andrew L and Szabó, Csaba and Bjertnaes, Lars J, American journal of respiratory and critical care medicine 166.11 (2002), 1436–1442 | Article

Activation of poly (ADP-Ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation
Liaudet, Lucas and Pacher, PáL and Mabley, Jon G and Virág, László and Soriano, Francisco G and HASKÓ, GYÖRGY and Szabó, Csaba, American journal of respiratory and critical care medicine 165.3 (2002), 372–377 | Article

Comparison of inflammation, organ damage, and oxidant stress induced by Salmonella enterica serovar Muenchen flagellin and serovar Enteritidis lipopolysaccharide
Liaudet, Lucas and Murthy, Kanneganti GK and Mabley, Jon G and Pacher, Pál and Soriano, Francisco G and Salzman, Andrew L and Szabó, Csaba, Infection and immunity 70.1 (2002), 192–198 | Article

Inosine exerts a broad range of antiinflammatory effects in a murine model of acute lung injury
Liaudet, Lucas and Mabley, Jon G and Pacher, Pál and Virág, László and Soriano, Francisco G and Marton, Anita and Haskó, György and Deitch, Edwin A and Szabó, Csaba, Annals of surgery 235.4 (2002), 568 | Article

NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes
Mabley, JG and Hasko, G and Liaudet, L and Soriano, F and Southan, GJ and Salzman, AL and Szabo, C, Journal of endocrinology 173.3 (2002), 457–464 | Article

Nicotine reduces the incidence of type I diabetes in mice
Mabley, JG and Pacher, P and Southan, GJ and Salzman, AL and Szabo, C, Journal of Pharmacology and Experimental Therapeutics 300.3 (2002), 876–881 | Article

Part II: beneficial effects of the peroxynitrite decomposition catalyst FP15 in murine models of arthritis and colitis.
Mabley, Jon G and Liaudet, Lucas and Pacher, Pál and Southan, Garry J and Groves, John T and Salzman, Andrew L and Szabó, Csaba, Molecular Medicine 8.10 (2002), 581 | Article

Hyperosmotic stress induces nuclear factor-kappaB activation and interleukin-8 production in human intestinal epithelial cells
Németh, Zoltán H and Deitch, Edwin A and Szabó, Csaba and Haskó, György, The American journal of pathology 161.3 (2002), 987–996 | Article

Lithium induces NF-kappaB activation and interleukin-8 production in human intestinal epithelial cells
Németh, Zoltán H and Deitch, Edwin A and Szabó, Csaba and Fekete, Zoltán and Hauser, Carl J and Haskó, György, Journal of Biological Chemistry 277.10 (2002), 7713–7719 | Article

Na+/H+ exchanger blockade inhibits enterocyte inflammatory response and protects against colitis
Németh, Zoltán H and Deitch, Edwin A and Szabó, Csaba and Mabley, Jon G and Pacher, Pál and Fekete, Zoltán and Hauser, Carl J and Hasko, Gyorgy, American Journal of Physiology-Gastrointestinal and Liver Physiology 283.1 (2002), G122–G132 | Article

NHE blockade inhibits chemokine production and NF-kappaB activation in immunostimulated endothelial cells
Németh, Zoltán H and Deitch, Edwin A and Lu, Qi and Szabó, Csaba and Haskó, György, American Journal of Physiology-Cell Physiology 283.2 (2002), C396–C403 | Article

Activation of poly (ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging
Pacher, Pal and Mabley, Jon G and Soriano, Francisco G and Liaudet, Lucas and Szabo, Csaba, International journal of molecular medicine 9.6 (2002), 659–664 | Article

Endothelial dysfunction in aging animals: the role of poly (ADP-ribose) polymerase activation
Pacher, Pál and Mabley, Jon G and Soriano, Francisco G and Liaudet, Lucas and Komjáti, Katalin and Szabó, Csaba, British journal of pharmacology 135.6 (2002), 1347–1350 | Article

Pharmacologic inhibition of poly (adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure
Pacher, Pál and Liaudet, Lucas and Mabley, Jon G and Komjáti, Katalin and Szabó, Csaba, Journal of the American College of Cardiology 40.5 (2002), 1006–1016 | Article

Role of poly (ADP-ribose) polymerase activation in endotoxin-induced cardiac collapse in rodents
Pacher, Pál and Cziráki, Attila and Mabley, Jon G and Liaudet, Lucas and Papp, Lajos and Szabó, Csaba, Biochemical pharmacology 64.12 (2002), 1785–1791 | Article

The role of poly (ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes
Pacher, Pal and Liaudet, Lucas and Soriano, Francisco Garcia and Mabley, Jon G and Szabó, éva and Szabó, Csaba, Diabetes 51.2 (2002), 514–521 | Article

Resistance to acute septic peritonitis in poly (ADP-ribose) polymerase-1-deficient mice
Soriano, Francisco Garcia and Liaudet, Lucas and Szabo, Eva and Virág, Lászlo and Mabley, Jon G and Pacher, Pál and Szabo, Csaba, Shock 17.4 (2002), 286–292 | Article

Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst.
Szabó, Csaba and Mabley, Jon G and Moeller, Suzanne M and Shimanovich, Roman and Pacher, Pál and Virág, László and Soriano, Francisco G and Van Duzer, John H and Williams, William and Salzman, Andrew L and others, Molecular Medicine 8.10 (2002), 571 | Article

Poly (ADP-ribose) polymerase inhibition reduces reperfusion injury after heart transplantation
Szabó, Gábor and Bährle, Susanne and Stumpf, Nicole and Sonnenberg, Karin and Szabó, éva and Pacher, Pál and Csont, Tamás and Schulz, Richard and Dengler, Thomas J and Liaudet, Lucas and others, Circulation research 90.1 (2002), 100–106 | Article

Poly (ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity
Szabó, Csaba and Zanchi, Anne and Komjáti, Katalin and Pacher, Pál and Krolewski, Andrzej S and Quist, William C and LoGerfo, Frank W and Horton, Edward S and Veves, Aristidis, Circulation 106.21 (2002), 2680–2686 | Article

Nitric oxide-peroxynitrite-poly (ADP-ribose) polymerase pathway in the skin
Virág, László and Szabó, éva and Bakondi, Edina and Bai, Péter and Gergely, Pál and Hunyadi, János and Szabó, Csaba, Experimental dermatology 11.3 (2002), 189–202 | Article

The therapeutic potential of poly (ADP-ribose) polymerase inhibitors
Virag, Laszlo and Szabó, Csaba, Pharmacological reviews 54.3 (2002), 375–429 | Article

Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite
Zhang, Xiaopeng and Chen, Jun and Graham, Steven H and Du, Lina and Kochanek, Patrick M and Draviam, Romesh and Guo, Fengli and Nathaniel, Paula D and Szabó, Csaba and Watkins, Simon C and others, Journal of neurochemistry 82.1 (2002), 181–191 | Article

Poly (ADP-ribose) polymerase inhibition in stroke: establishment of the therapeutic window of intervention and delineation of its role in the patgogenesis of white matter damage in FASEB JOURNAL
Komjati, K and Jagtap, P and Baloglu, E and Van Duzer, J and Salzman, A and Szabó, C ( FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA, 2002), A599–A599 | Chapter

FP 15, a novel, potent peroxynitrite decomposition catalyst: in vitro cytoprotective actions and protection against diabetes mellitus and diabetic cardiovascular complications in Faseb Journal
Szabó, C and Mabley, JG and Moeller, SM and Shimanovich, R and Pacher, P and Virag, L and Salzman, A and Groves, JT ( FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA, 2002), A1166–A1166 | Chapter

Effects of combined selective iNOS inhibition and peroxynitrite blockade during endotoxemia in pigs.
Ploner, Franz and Radermacher, Peter and Theisen, Marc and Tugtekin, Ilvas F and Matejovic, Martin and Stehr, Alexander and Szabo, Csaba and Southan, Garry J and Georgieff, Michael and Bruckner, Uwe B and others, Shock (Augusta, Ga.) 16.2 (2001), 130–136 | Article

Production of interleukin-12 is under the control of endogenous interleukin-10 in myocardial ischemia-reperfusion.
Yang, Zequan and Szabó, Csaba, Shock (Augusta, Ga.) 15.1 (2001), 77–79 | Article

Protective effects of PJ34, a novel, potent inhibitor of poly (ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke
Abdelkarim, Galaleldin E and Gertz, Karen and Harms, Christoph and Katchanov, Juri and Dirnagl, Ulrich and Szabo, Csaba and Endres, Matthias, International journal of molecular medicine 7.3 (2001), 255–260 | Article

Partial protection by poly (ADP-ribose) polymerase inhibitors from nitroxyl-induced cytotoxity in thymocytes
Bai, Péter and Bakondi, Edina and Szabó, éva and Gergely, Pál and Szabó, Csaba and VIRag, Laszlo, Free Radical Biology and Medicine 31.12 (2001), 1616–1623 | Article

Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: IkappaBalpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction
Eaves-Pyles, Tonyia and Murthy, Kanneganti and Liaudet, Lucas and Virág, László and Ross, Gary and Soriano, Francisco Garcia and Szabó, Csaba and Salzman, Andrew L, The Journal of Immunology 166.2 (2001), 1248–1260 | Article

Sulphasalazine inhibits macrophage activation: inhibitory effects on inducible nitric oxide synthase expression, interleukin-12 production and major histocompatibility complex II expression
Haskó, György and Szabó, Csaba and Németh, Zoltán H and Deitch, Edwin A, Immunology 103.4 (2001), 473–478 | Article

Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells
Lakey, Jonathan RT and Suarez-Pinzon, Wilma L and Strynadka, Ken and Korbutt, Gregory S and Rajotte, Ray V and Mabley, Jon G and Szabó, Csaba and Rabinovitch, Alex, Laboratory investigation 81.12 (2001), 1683 | Article

Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture
Liaudet, Lucas and Mabley, Jon G and Soriano, Francisco Garcia and Pacher, Pal and Marton, Anita and Hasko, Gyorgy and Szabo, Csaba, American Journal of Respiratory and Critical Care Medicine 164.7 (2001), 1213–1220 | Article

Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase
Liaudet, Lucas and Yang, Zequan and Al-Affar, El-Bachir and Szabó, Csaba, Molecular Medicine 7.6 (2001), 406–417 | Article

Suppression of poly (ADP-ribose) polymerase activation by 3-aminobenzamide in a rat model of myocardial infarction: long-term morphological and functional consequences
Liaudet, Lucas and Szabó, éva and Timashpolsky, Leonid and Virág, László and Cziráki, Attila and Szabó, Csaba, British journal of pharmacology 133.8 (2001), 1424–1430 | Article

Evidence for the expression of cyclooxygenase-2 enzyme in periodontitis
Lohinai, Z and Stachlewitz, R and Szekely, AD and Feher, E and Dézsi, L and Szabó, C, Life sciences 70.3 (2001), 279–290 | Article

Evidence for reactive nitrogen species formation in the gingivomucosal tissue
Lohinai, Z and Stachlewitz, R and Virag, L and Szekely, AD and Hasko, G and Szabo, C, Journal of dental research 80.2 (2001), 470–475 | Article

Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase
Mabley, JG and Jagtap, P and Perretti, Mauro and Getting, Stephen J and Salzman, Andrew L and Virag, L and Szabo, E and Soriano, FG and Liaudet, L and Abdelkarim, GE and others, Inflammation Research 50.11 (2001), 561–569 | Article

Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1, 2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes
Mabley, Jon G and Suarez-Pinzon, Wilma L and Haskó, György and Salzman, Andrew L and Rabinovitch, Alex and Kun, Ernest and Szabó, Csaba, British journal of pharmacology 133.6 (2001), 909–919 | Article

Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro
Marton, Anita and Pacher, Pal and Murthy, Kanneganti G and Nemeth, Zoltan H and Hasko, Gyorgy and Szabo, Csaba, International journal of molecular medicine 8.6 (2001), 617–621 | Article

Inhibition of the Na+/H+ antiporter suppresses IL-12 p40 production by mouse macrophages
Németh, Zoltán H and Mabley, John G and Deitch, Edwin A and Szabó, Csaba and Haskó, György, Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1539.3 (2001), 233–242 | Article

Effect of mercaptoethylguanidine scavengers of peroxynitrite on the development of experimental allergic encephalomyelitis in PLSJL mice
Scott, Gwen S and Kean, Rhonda B and Southan, Garry J and Szabó, Csaba and Hooper, D Craig, Neuroscience letters 311.2 (2001), 125–128 | Article

Role of poly (ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis
Scott, GS and Hake, P and Kean, RB and Virag, L and Szabo, C and Hooper, DC, Journal of neuroimmunology 117.1-2 (2001), 78–86 | Article

Role of nitric oxide in vascular permeability after combined burns and smoke inhalation injury
Soejima, Kazutaka and Traber, Lillian D and Schmalstieg, Frank C and Hawkins, Hal and Jodoin, Jeffrey M and Szabo, Csaba and Szabo, Eva and Varig, Lasio and Salzman, Andrew and Traber, Daniel L, American journal of respiratory and critical care medicine 163.3 (2001), 745–752 | Article

Role of nitric oxide in myocardial dysfunction after combined burn and smoke inhalation injury
Soejima, Kazutaka and Schmalstieg, Frank C and Traber, Lilian D and Szabo, Csaba and Salzman, Andrew and Traber, Daniel L, Burns 27.8 (2001), 809–815 | Article

Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly (ADP-ribose) polymerase activation
Soriano, Francisco and Virág, László and Szabó, Csaba, Journal of molecular medicine 79.8 (2001), 437–448 | Article

Diabetic endothelial dysfunction: the role of poly (ADP-ribose) polymerase activation
Soriano, Francisco Garcia and Virág, László and Jagtap, Prakash and Szabo, Eva and Mabley, Jon G and Liaudet, Lucas and Marton, Anita and Hoyt, Dale G and Murthy, Kanneganti GK and Salzman, Andrew L and others, Nature medicine 7.1 (2001), 108 | Article

Inosine improves gut permeability and vascular reactivity in endotoxic shock
Soriano, Francisco Garcia and Liaudet, Lucas and Marton, Anita and Haskó, György and Lorigados, Clara Batista and Deitch, Edwin A and Szabó, Csaba, Critical care medicine 29.4 (2001), 703–708 | Article

Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly (ADP-ribose) polymerase
Soriano, Francisco Garcia and Pacher, Pál and Mabley, Jon and Liaudet, Lucas and Szabó, Csaba, Circulation research 89.8 (2001), 684–691 | Article

An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice
Suarez-Pinzon, Wilma L and Mabley, Jon G and Strynadka, Ken and Power, Robert F and Szabo, Csaba and Rabinovitch, Alex, Journal of autoimmunity 16.4 (2001), 449–455 | Article

Peroxynitrite production, DNA breakage, and poly (ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity
Szabó, éva and Virág, László and Bakondi, Edina and Gyüre, László and Haskó, György and Bai, Péter and Hunyadi, János and Gergely, Pál and Szabó, Csaba, Journal of investigative dermatology 117.1 (2001), 74–80 | Article

Purines inhibit poly (ADP-ribose) polymerase activation and modulate oxidant-induced cell death
Virág, László and Szabó, Csaba, The FASEB Journal 15.1 (2001), 99–107 | Article

Nitric oxide in skeletal muscle: inhibition of nitric oxide synthase inhibits walking speed in rats
Wang, Min-Xia and Murrell, Dédée F and Szabo, Csaba and Warren, Russell F and Sarris, Maria and Murrell, George AC, Nitric oxide 5.3 (2001), 219–232 | Article

Adenovirus infection increases iNOS and peroxynitrite production in the lung
Zsengellér, Zsuzsanna K and Ross, Gary F and Trapnell, Bruce C and Szabó, Csaba and Whitsett, Jeffrey A, American Journal of Physiology-Lung Cellular and Molecular Physiology 280.3 (2001), L503–L511 | Article