Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts
Shved, N. and Warsow, G. and Eichinger, F. and Hoogewijs, D. and Brandt, S. and Wild, P. and Kretzler, M. and Cohen, C. D. and Lindenmeyer, M. T., Sci Rep 7.1 (2017), 8576 | Article

Oxygen-dependent regulation of aquaporin-3 expression
Hoogewijs, D. and Vogler, M. and Zwenger, E. and Krull, S. and Zieseniss, A., Hypoxia 4 (2016), 91-97 | Article

ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models
Brooks, D. L. and Schwab, L. P. and Krutilina, R. and Parke, D. N. and Sethuraman, A. and Hoogewijs, D. and Schorg, A. and Gotwald, L. and Fan, M. and Wenger, R. H. and Seagroves, T. N., Mol Cancer 15 (2016), 26 | Article

Bidirectional signalling between EphA2 and ephrinA1 increases tubular cell attachment, laminin secretion and modulates erythropoietin expression after renal hypoxic injury
Rodriguez, S. and Rudloff, S. and Koenig, K. F. and Karthik, S. and Hoogewijs, D. and Huynh-Do, U., Pflugers Arch 468.8 (2016), 1433-48 | Article

Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2alpha in invasive breast cancer cells
Fuady, J. H. and Gutsche, K. and Santambrogio, S. and Varga, Z. and Hoogewijs, D. and Wenger, R. H., Oncotarget 7.21 (2016), 31153-65 | Article

Frequently asked questions in hypoxia research
Wenger, R. H. and Kurtcuoglu, V. and Scholz, C. C. and Marti, H. H. and Hoogewijs, D., Hypoxia 3 (2015), 35-43 | Article

Induction of long noncoding RNA MALAT1 in hypoxic mice
Lelli, A. and Nolan, K. A. and Santambrogio, S. and Goncalves, A. F. and Schonenberger, M. J. and Guinot, A. and Frew, I. J. and Marti, H. H. and Hoogewijs, D. and Wenger, R. H., Hypoxia 3 (2015), 45-52 | Article

A globin domain in a neuronal transmembrane receptor of Caenorhabditis elegans and Ascaris suum: molecular modeling and functional properties
Tilleman, L. and Germani, F. and De Henau, S. and Helbo, S. and Desmet, F. and Berghmans, H. and Van Doorslaer, S. and Hoogewijs, D. and Schoofs, L. and Braeckman, B. P. and Moens, L. and Fago, A. and Dewilde, S., J Biol Chem 290.16 (2015), 10336-52 | Article

Destruction of a distal hypoxia response element abolishes trans-activation of the PAG1 gene mediated by HIF-independent chromatin looping
Schorg, A. and Santambrogio, S. and Platt, J. L. and Schodel, J. and Lindenmeyer, M. T. and Cohen, C. D. and Schrodter, K. and Mole, D. R. and Wenger, R. H. and Hoogewijs, D., Nucleic Acids Res 43.12 (2015), 5810-23 | Article

Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IkappaB
Muller-Edenborn, K. and Leger, K. and Glaus Garzon, J. F. and Oertli, C. and Mirsaidi, A. and Richards, P. J. and Rehrauer, H. and Spielmann, P. and Hoogewijs, D. and Borsig, L. and Hottiger, M. O. and Wenger, R. H., Oncotarget 6.24 (2015), 20288-301 | Article

Phylogeny of Echinoderm Hemoglobins
Christensen, A. B. and Herman, J. L. and Elphick, M. R. and Kober, K. M. and Janies, D. and Linchangco, G. and Semmens, D. C. and Bailly, X. and Vinogradov, S. N. and Hoogewijs, D., PLoS One 10.8 (2015), e0129668 | Article

Hemoglobins in the genome of the cryptomonad Guillardia theta
Smith, D. R. and Vinogradov, S. N. and Hoogewijs, D., Biol Direct 9 (2014), 7 | Article

The role of PHD2 mutations in the pathogenesis of erythrocytosis
Gardie, B. and Percy, M. J. and Hoogewijs, D. and Chowdhury, R. and Bento, C. and Arsenault, P. R. and Richard, S. and Almeida, H. and Ewing, J. and Lambert, F. and McMullin, M. F. and Schofield, C. J. and Lee, F. S., Hypoxia 2 (2014), 71-90 | Article

Hypoxia-inducible factor-mediated induction of WISP-2 contributes to attenuated progression of breast cancer
Fuady, J. H. and Bordoli, M. R. and Abreu-Rodriguez, I. and Kristiansen, G. and Hoogewijs, D. and Stiehl, D. P. and Wenger, R. H., Hypoxia 2 (2014), 23-33 | Article

A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression
Storti, F. and Santambrogio, S. and Crowther, L. M. and Otto, T. and Abreu-Rodriguez, I. and Kaufmann, M. and Hu, C. J. and Dame, C. and Fandrey, J. and Wenger, R. H. and Hoogewijs, D., Haematologica 99.4 (2014), e45-8 | Article

Microbial eukaryote globins
Vinogradov, S. N. and Bailly, X. and Smith, D. R. and Tinajero-Trejo, M. and Poole, R. K. and Hoogewijs, D., Adv Microb Physiol 63 (2013), 391-446 | Article

Bacterial and archaeal globins - a revised perspective
Vinogradov, S. N. and Tinajero-Trejo, M. and Poole, R. K. and Hoogewijs, D., Biochim Biophys Acta 1834.9 (2013), 1789-800 | Article

GLB-13 is associated with oxidative stress resistance in Caenorhabditis elegans
Ren, C. and Li, Y. and Han, R. and Gao, D. and Li, W. and Shi, J. and Hoogewijs, D. and Braeckman, B. P. and De Henau, S. and Lu, Y. and Qu, W. and Gao, Y. and Wu, Y. and Li, Z. and Liu, H. and Wang, Z. and Zhang, C., IUBMB Life 65.5 (2013), 423-34 | Article

Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression
Regan Anderson, T. M. and Peacock, D. L. and Daniel, A. R. and Hubbard, G. K. and Lofgren, K. A. and Girard, B. J. and Schorg, A. and Hoogewijs, D. and Wenger, R. H. and Seagroves, T. N. and Lange, C. A., Cancer Res 73.18 (2013), 5810-20 | Article

The evolution of land plant hemoglobins
Vazquez-Limon, C. and Hoogewijs, D. and Vinogradov, S. N. and Arredondo-Peter, R., Plant Sci 191-192 (2012), 71-81 | Article

Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia
Ladroue, C. and Hoogewijs, D. and Gad, S. and Carcenac, R. and Storti, F. and Barrois, M. and Gimenez-Roqueplo, A. P. and Leporrier, M. and Casadevall, N. and Hermine, O. and Kiladjian, J. J. and Baruchel, A. and Fakhoury, F. and Bressac-de Paillerets, B. and Feunteun, J. and Mazure, N. and Pouyssegur, J. and Wenger, R. H. and Richard, S. and Gardie, B., Haematologica 97.1 (2012), 9-14 | Article

Androglobin: a chimeric globin in metazoans that is preferentially expressed in Mammalian testes
Hoogewijs, D. and Ebner, B. and Germani, F. and Hoffmann, F. G. and Fabrizius, A. and Moens, L. and Burmester, T. and Dewilde, S. and Storz, J. F. and Vinogradov, S. N. and Hankeln, T., Mol Biol Evol 29.4 (2012), 1105-14 | Article

A phylogenetic analysis of the globins in fungi
Hoogewijs, D. and Dewilde, S. and Vierstraete, A. and Moens, L. and Vinogradov, S. N., PLoS One 7.2 (2012), e31856 | Article

Evolution of the globin gene family in deuterostomes: lineage-specific patterns of diversification and attrition
Hoffmann, F. G. and Opazo, J. C. and Hoogewijs, D. and Hankeln, T. and Ebner, B. and Vinogradov, S. N. and Bailly, X. and Storz, J. F., Mol Biol Evol 29.7 (2012), 1735-45 | Article

What are the origins and phylogeny of plant hemoglobins?
Vinogradov, S. N. and Hoogewijs, D. and Arredondo-Peter, R., Commun Integr Biol 4.4 (2011), 443-5 | Article

Phylogenetic relationships of 3/3 and 2/2 hemoglobins in Archaeplastida genomes to bacterial and other eukaryote hemoglobins
Vinogradov, S. N. and Fernandez, I. and Hoogewijs, D. and Arredondo-Peter, R., Mol Plant 4.1 (2011), 42-58 | Article

Globins in Caenorhabditis elegans
Tilleman, L. and Germani, F. and De Henau, S. and Geuens, E. and Hoogewijs, D. and Braeckman, B. P. and Vanfleteren, J. R. and Moens, L. and Dewilde, S., IUBMB Life 63.3 (2011), 166-74 | Article

Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom
Kiger, L. and Tilleman, L. and Geuens, E. and Hoogewijs, D. and Lechauve, C. and Moens, L. and Dewilde, S. and Marden, M. C., PLoS One 6.6 (2011), e20478 | Article

The putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation
Hasgall, P. A. and Hoogewijs, D. and Faza, M. B. and Panse, V. G. and Wenger, R. H. and Camenisch, G., PLoS One 6.7 (2011), e22107 | Article

Globin-like proteins in Caenorhabditis elegans: in vivo localization, ligand binding and structural properties
Geuens, E. and Hoogewijs, D. and Nardini, M. and Vinck, E. and Pesce, A. and Kiger, L. and Fago, A. and Tilleman, L. and De Henau, S. and Marden, M. C. and Weber, R. E. and Van Doorslaer, S. and Vanfleteren, J. and Moens, L. and Bolognesi, M. and Dewilde, S., BMC Biochem 11 (2010), 17 | Article

Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
Wenger, R. H. and Hoogewijs, D., Am J Physiol Renal Physiol 298.6 (2010), F1287-96 | Article

Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans
Hoogewijs, D. and Houthoofd, K. and Matthijssens, F. and Vandesompele, J. and Vanfleteren, J. R., BMC Mol Biol 9 (2008), 9 | Article

The Caenorhabditis globin gene family reveals extensive nematode-specific radiation and diversification
Hoogewijs, D. and De Henau, S. and Dewilde, S. and Moens, L. and Couvreur, M. and Borgonie, G. and Vinogradov, S. N. and Roy, S. W. and Vanfleteren, J. R., BMC Evol Biol 8 (2008), 279 | Article

Dietary restriction by growth in axenic medium induces discrete changes in the transcriptional output of genes involved in energy metabolism in Caenorhabditis elegans
Castelein, N. and Hoogewijs, D. and De Vreese, A. and Braeckman, B. P. and Vanfleteren, J. R., Biotechnol J 3.6 (2008), 803-12 | Article

Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family
Hoogewijs, D. and Geuens, E. and Dewilde, S. and Vierstraete, A. and Moens, L. and Vinogradov, S. and Vanfleteren, J. R., BMC Genomics 8 (2007), 356 | Article

A model of globin evolution
Vinogradov, S. N. and Hoogewijs, D. and Bailly, X. and Mizuguchi, K. and Dewilde, S. and Moens, L. and Vanfleteren, J. R., Gene 398.1-2 (2007), 132-42 | Article

Neuroglobin and cytoglobin as potential enzyme or substrate
Trandafir, F. and Hoogewijs, D. and Altieri, F. and Rivetti di Val Cervo, P. and Ramser, K. and Van Doorslaer, S. and Vanfleteren, J. R. and Moens, L. and Dewilde, S., Gene 398.1-2 (2007), 103-13 | Article

Characterization of a globin-coupled oxygen sensor with a gene-regulating function
Thijs, L. and Vinck, E. and Bolli, A. and Trandafir, F. and Wan, X. and Hoogewijs, D. and Coletta, M. and Fago, A. and Weber, R. E. and Van Doorslaer, S. and Ascenzi, P. and Alam, M. and Moens, L. and Dewilde, S., J Biol Chem 282.52 (2007), 37325-40 | Article

From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia
Hoogewijs, D. and Terwilliger, N. B. and Webster, K. A. and Powell-Coffman, J. A. and Tokishita, S. and Yamagata, H. and Hankeln, T. and Burmester, T. and Rytkonen, K. T. and Nikinmaa, M. and Abele, D. and Heise, K. and Lucassen, M. and Fandrey, J. and Maxwell, P. H. and Pahlman, S. and Gorr, T. A., Integr Comp Biol 47.4 (2007), 552-77 | Article

A phylogenomic profile of globins
Vinogradov, S. N. and Hoogewijs, D. and Bailly, X. and Arredondo-Peter, R. and Gough, J. and Dewilde, S. and Moens, L. and Vanfleteren, J. R., BMC Evol Biol 6 (2006), 31 | Article

Three globin lineages belonging to two structural classes in genomes from the three kingdoms of life
Vinogradov, S. N. and Hoogewijs, D. and Bailly, X. and Arredondo-Peter, R. and Guertin, M. and Gough, J. and Dewilde, S. and Moens, L. and Vanfleteren, J. R., Proc Natl Acad Sci U S A 102.32 (2005), 11385-9 | Article

Modulation of oxygen binding to insect hemoglobins: the structure of hemoglobin from the botfly Gasterophilus intestinalis
Pesce, A. and Nardini, M. and Dewilde, S. and Hoogewijs, D. and Ascenzi, P. and Moens, L. and Bolognesi, M., Protein Sci 14.12 (2005), 3057-63 | Article

Metabolism, physiology and stress defense in three aging Ins/IGF-1 mutants of the nematode Caenorhabditis elegans
Houthoofd, K. and Fidalgo, M. A. and Hoogewijs, D. and Braeckman, B. P. and Lenaerts, I. and Brys, K. and Matthijssens, F. and De Vreese, A. and Van Eygen, S. and Munoz, M. J. and Vanfleteren, J. R., Aging Cell 4.2 (2005), 87-95 | Article

Genome-wide analysis of the globin gene family of C. elegans
Hoogewijs, D. and Geuens, E. and Dewilde, S. and Moens, L. and Vierstraete, A. and Vinogradov, S. and Vanfleteren, J., IUBMB Life 56.11-12 (2004), 697-702 | Article

Nerve globins in invertebrates
Geuens, E. and Dewilde, S. and Hoogewijs, D. and Pesce, A. and Nienhaus, K. and Nienhaus, G. U. and Olson, J. and Vanfleteren, J. and Bolognesi, M. and Moens, L., IUBMB Life 56.11-12 (2004), 653-6 | Article