D. Glauser publications

Publications list


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Thapliyal, S, Beets, I, & Glauser, DA (2023). Multisite regulation integrates multimodal context in sensory circuits to control persistent behavioral states in C. elegans. Nature communications14(1), 3052. https://doi.org/10.1038/s41467-023-38685-1


Ippolito, D, & Glauser, DA (2023). Multiple antagonist calcium-dependent mechanisms control CaM kinase-1 subcellular localization in a C. elegans thermal nociceptor. eLife12, e85260. https://doi.org/10.7554/eLife.85260


Jordan, A., & Glauser, DA (2023). Distinct clusters of human pain gene orthologs in Caenorhabditis elegans regulate thermo-nociceptive sensitivity and plasticity. Genetics224(1), iyad047. https://doi.org/10.1093/genetics/iyad047




Glauser DA (2022). Temperature sensing and context-dependent thermal behavior in nematodes. Current opinion in neurobiology73, 102525. 






Ippolito, D, Thapliyal, S, & Glauser, DA (2021). Ca2+/CaM binding to CaMKI promotes IMA-3 importin binding and nuclear translocation in sensory neurons to control behavioral adaptation. eLife10, e71443.


Marques, F, Falquet, L, Vandewyer, E, Beets, I, & Glauser, DA (2021). Signaling via the FLP-14/FRPR-19 neuropeptide pathway sustains nociceptive response to repeated noxious stimuli in C. elegansPLoS genetics17(11), e1009880. 


Brenna, A, Ripperger, JA, Saro, G, Glauser, DA, Yang, Z, & Albrecht, U (2021). PER2 mediates CREB-dependent light induction of the clock gene Per1. Scientific reports11(1), 21766.


Gómez-Saldivar, G, Glauser, DA*, & Meister, P* (2021). Tissue-specific DamID protocol using nanopore sequencing. Journal of biological methods8(3), e152.

*corresponding authors




Gómez-Saldivar G, Osuna-Luque J, Semple JI, Glauser DA*, Jarriault S* & Meister P* (2020). Tissue-Specific Transcription Footprinting Using RNA PoI DamID (RAPID) in Caenorhabditis elegans. Genetics 216 (4), 931-945 1

*corresponding authors


Marques F, Thapliyal S, Javer A, Shrestha P, Brown AEX & Glauser DA (2020) Tissue-specific isoforms of the single C. elegans Ryanodine receptor gene unc-68 control specific functions. PLoS genetics 16 (10), e1009102


Saro G, Lia AS, Thapliyal S, Marques F, Busch KE & Glauser DA (2020) Specific Ion Channels Control Sensory Gain, Sensitivity, and Kinetics in a Tonic Thermonociceptor. Cell Reports 30 (2), 397-408. e4 5


Lia AS & Glauser DA (2020). A system for the high-throughput analysis of acute thermal avoidance and adaptation in C. elegans. Journal of Biological Methods 7 (1)





Marques F, Saro G, Lia AS, Poole RJ, Falquet L & Glauser DA (2019) Identification of avoidance genes through neural pathway-specific forward optogenetics. PLoS Genetics 15 (12)




Lim JP, Fehlauer H, Das A, Saro G, Glauser DA, Brunet A & Goodman MB (2018). Loss of CaMKI function disrupts salt aversive learning in C. elegansJournal of Neuroscience, 1611-17




Hostettler L, Grundy L, Käser-Pébernard S, Wicky C, William Schafer R & Glauser DA (2017). The bright fluorescent protein mNeonGreen facilitates protein expression analysis in vivoG3 (Genes, Genetics, Genomes) 7: 607-615.




Glauser DA & Goodman MB (2016). Molecules empowering animals to sense and respond to temperature in changing environments. Current Opinion in Neurobiology 41: 92-98 (online DOI:10.1016/j.conb.2016.09.006).




Schild LC & Glauser DA (2015). Dual color neural activation and behavior control with chrimson and CoChR in Caenorhabditis elegans. Genetics 200: 1029-1034 (online doi: 10.1534/genetics.115.17795). 




Schild LC, Zbinden L, Bell HW, Yu YV, Sengupta P, Goodmanemail MB & Glauser DA (2014). The balance between cytoplasmic and nuclear CaM Kinase-1 signaling controls the operating range of noxious heat avoidance. Neuron  84: 983-996.

Yu YV, Bell HW, Glauser DA, Van Hooser SD, Goodman MB & Sengupta P (2014). CaMKI-Dependent regulation of sensory gene expression mediates experience-dependent plasticity in the operating range of a thermosensory neuron. Neuron 84: 919-926.
Bou Dib P, Gnägi B, Daly F, Sabado V, Tas D, Glauser DA, Peter Meister P & Nagoshi E (2014). A Conserved Role for p48 Homologs in Protecting Dopaminergic Neurons from Oxidative Stress. PLoS Genetics 10(10):e1004718 (DOI: 10.1371/journal.pgen.1004718.
Glauser DA (2014). The multiplicity of alternative splicing decisions in Caenorhabditis elegans is linked to specific intronic regulatory motifs and minisatellites. BMC Genomics 15:354, doi: 10.1186/1471-2164-15-364.
Glauser DA (2013). How and why Caenorhabitis elegans uses distinct escape and avoidance regimes to minimise exposure to noxious heat. Worm 2(4): doi:10.4161/worm.27285. 


Rufener L, Bedoni N, Baur R, Rey S, Glauser DA, Bouvier J, Beech R, Sigel E & Puoti A (2013).
acr-23 Encodes a monepantel-sensitive channel in Caenorhabditis elegans. PLoS Pathogens 9(8) e1003524. doi:10.1371/journal.ppat.1003524.


Schild LC & Glauser DA (2013). Dynamic switching between escape and avoidance regimes reduces Caenorhabditis elegans exposure to noxious heat. Nature Communications 4: #2198, doi:10.1038/ncomms31




Glauser DA, Johnson BE, Aldrich RW & Goodman MB (2011). Intragenic alternative splicing coordination is essential for Caenorhabditis elegans slo-1 gene function. Proc. Nat. Acad. Sci. (USA) 108: 20790-20795. 


Johnson BE, Glauser DA, Dan-Glauser ES, Halling DB, Aldrich RW & Goodman MB. (2011). Alternatively spliced doamins interact to regulate BK potassium channel gating. Proc. Nat. Acad. Sci. (USA) 108: 20784-20789.


Geffeney SL, Cueva JG, Glauser DA, Doll JC, Lee TH, Montoya M, Karania S, Garakani AM, Pruitt BL & Goodman MB (2011). DEG/ENaC but not TRP channels are the major mechanoelectrical transduction channels in a C. elegans nociceptor. Neuron 71: 845-857.


Glauser DA, Chen WC, Agin R,  MacInnis BL,  Hellman AB,  Garrity PA, Tan MW & Goodman MB (2011). Heat avoidance is regulated by transient receptor potential (TRP) channels and a neuropeptide signaling pathway in Caenorhabditis elegans. Genetics 188: 91-103.


Ryser S, Glauser D, Vigier M, Zhang YQ, Tachini P, Schlegel W, Durand P & Irminger-Finger I (2011). Gene expression of rat spermatogonia and Sertoli cells reveals signaling pathways from stem cells to niche and testicular cancer cells to surrounding stroma. BMC Genomics #29. 




Glauser DA & Goodman MB (2010). Neuropeptides strike back. Nature Neuroscience 13: 528-529. 




Glauser DA & Schlegel W (2009). The FoxO/Bcl-6/cyclin D2 pathway mediates metabolic and growth factor stimulation of proliferation in Min6 pancreatic β-cells. J Recept


Signal Transduct Res. 29: 293-298.

Walters EM, Garcia-Serres R, Naik SG, Bourquin F, Glauser DA, Schürmann P, Huynh BH & Johnson MK (2009). Role of Histidine-86 in the Catalytic Mechanism of Ferredoxin: Thioredoxin Reductase. Biochemistry 48: 1016-1024.




Glauser DA & Schlegel W (2008). FoxO proteins in pancreatic β cells as potential therapeutic targets in diabetes (2008). Expert Review of Endocrinology and Metabolism 3: 175-185.




Glauser DA & Schlegel W (2007). The emerging role of FOXO transcription factors in pancreatic β cells. J Endocrinol. 193: 195-207.


Dai S, Friemann R, Glauser DA, Bourquin F, Manieri W, Schürmann P & Eklund H (2007). Structural Snapshots along the Reaction Pathway of Ferredoxin:Thioredoxin Reductase. Nature 448: 92-96.


Glauser DA, Brun T, Gauthier BR & Schlegel W (2007). Transcriptional response of pancreatic beta cells to metabolic stimulation: large scale identification of immediate-early and secondary response genes. BMC Mol Biol. 8: #54.


Glauser DA & Schlegel W (2007). Sequential actions of ERK1/2 on AP-1 transcription factor allow temporal integration of metabolic signals in pancreatic β cells. FASEB J. 21: 3240-3249.




Glauser DA & Schlegel W (2006). Mechanisms of transcriptional regulation underlying temporal integration of signals. Nucleic Acids Research 34: 5175-5183.




Walters EM, Garcia-Serres R, Jameson GN, Glauser DA, Bourquin F, Manieri W, Schürmann P, Johnson MK & Huynh BH (2005). Spectroscopic characterization of site-specific [Fe(4)S(4)] cluster chemistry in ferredoxin:thioredoxin reductase: implications for the catalytic mechanism. J Am Chem Soc 127: 9612-9624.




Glauser DA, Bourquin F, Manieri W & Schurmann P (2004). Characterization of ferredoxin:thioredoxin reductase modified by site-directed mutagenesis. J Biol Chem 279: 16662-16669.