Details

Fakultät	Math.-Nat. und Med. Fakultät
Bereich	Biologie
Code	UE-SBL.00115
Sprachen	Englisch
Art der Unterrichtseinheit	Vorlesung
Kursus	Master
Semester	SA-2022

Zeitplan und Räume

Vorlesungszeiten	Dienstag 08:15 - 11:00, Wöchentlich (Herbstsemester)
Strukturpläne	3h par semaine durant 4 semaines à choix
Kontaktstunden	12

Unterricht

Verantwortliche	Puoti Alessandro
Dozenten-innen	Puoti Alessandro
Beschreibung	The flow of genetic information goes from DNA to RNA, and from RNA to proteins. The question is how could the first proteins be made if they are needed for transcription and translation? The hypothesis of the RNA world suggests that catalytic RNAs (ribozymes) may have preceded proteins. This lecture will briefly describe the origins of life and emphasize the importance of ribozymes, their mode of action and their roles in today's world. Other themes include the discovery and mechanism of RNA interference, the importance of small and long non-coding RNAs, RNA-based technologies including RNA vaccines, the evolution of RNA-based adaptive CRISPR immunity.
Lernziele	DNA is best known to be transcribed into RNA which is then translated into protein. However, during the last decades, it has become clear that RNA also plays essential roles in the regulation of gene expression and catalysis. Students will discover the relevance of non-coding RNAs and their functions. From the catalytic role of RNAs in the "RNA World" when life has appeared on Earth, to the latest findings on RNA-mediated gene silencing, the lecture focuses on functions of RNAs that were totally unexpected.
Bemerkungen	Given in 4 x 3 hours
Soft Skills	Nein
ausserhalb des Bereichs	Nein
BeNeFri	Ja
Mobilität	Ja
UniPop	Nein

Mündliche Prüfung - SA-2022, Wintersession 2023

Datum	13.02.2023 08:25 - 14:30
Bewertungsmodus	Nach Note
Beschreibung	Oral exam, 15 min. One mark.

Mündliche Prüfung - SP-2023, Herbstsession 2023

Datum	13.09.2023 13:00 - 13:30
Bewertungsmodus	Nach Note
Beschreibung	Oral exam, 15 min. One mark.