Détails

Faculté	Faculté des sciences et de médecine
Domaine	Biologie
Code	UE-SBL.00115
Langues	Anglais
Type d'enseignement	Cours
Cursus	Master
Semestre(s)	SA-2022

Horaires et salles

Horaire résumé	Mardi 08:15 - 11:00, Hebdomadaire (Semestre d'automne)
Struct. des horaires	3h par semaine durant 4 semaines à choix
Heures de contact	12

Enseignement

Responsables	Puoti Alessandro
Enseignants	Puoti Alessandro
Description	The flow of genetic information goes from DNA to RNA, and from RNA to proteins. The question is how could the first proteins be made if they are needed for transcription and translation? The hypothesis of the RNA world suggests that catalytic RNAs (ribozymes) may have preceded proteins. This lecture will briefly describe the origins of life and emphasize the importance of ribozymes, their mode of action and their roles in today's world. Other themes include the discovery and mechanism of RNA interference, the importance of small and long non-coding RNAs, RNA-based technologies including RNA vaccines, the evolution of RNA-based adaptive CRISPR immunity.
Objectifs de formation	DNA is best known to be transcribed into RNA which is then translated into protein. However, during the last decades, it has become clear that RNA also plays essential roles in the regulation of gene expression and catalysis. Students will discover the relevance of non-coding RNAs and their functions. From the catalytic role of RNAs in the "RNA World" when life has appeared on Earth, to the latest findings on RNA-mediated gene silencing, the lecture focuses on functions of RNAs that were totally unexpected.
Commentaire	Given in 4 x 3 hours
Softskills	Non
Hors domaine	Non
BeNeFri	Oui
Mobilité	Oui
UniPop	Non

Examen oral - SA-2022, Session d'hiver 2023

Date	13.02.2023 08:25 - 14:30
Mode d'évaluation	Par note
Description	Oral exam, 15 min. One mark.

Examen oral - SP-2023, Session d'automne 2023

Date	13.09.2023 13:00 - 13:30
Mode d'évaluation	Par note
Description	Oral exam, 15 min. One mark.