Dendritic spine loss deep in the neocortex and dendrite distortion with diffusion disturbances occur early in experimental pneumococcal meningitis
Baronti, D. and Tomov, N. and Hupp, S. and Mitchell, T.J. and Iliev, A.I., Frontiers in Neuroscience (2023) | Artikel
Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes
Müller, A. and Lekhuleni, C. and Hupp, S. and du Plessis, M. and Holivololona, L. and Babiychuk, E. and Leib, S.L. and Grandgirard, D. and Iliev, A.I. and von Gottberg, A. and Hathaway, L.J., Frontiers in Cellular and Infection Microbiology (2023) | Artikel
Easy to build cost-effective acute brain slice incubation system for parallel analysis of multiple treatment conditions
Hupp, S. and Tomov, N.S. and Bischoff, C. and Baronti, D. and Iliev, A.I., Journal of Neuroscience Methods (2022) | Artikel
Pneumolysin boosts the neuroinflammatory response to Streptococcus pneumoniae through enhanced endocytosis
Hupp, S. and Förtsch, C. and Graber, F. and Mitchell, T.J. and Iliev, A.I., Nature Communications (2022) | Artikel
The inflammatory response and neuronal injury in Streptococcus suis meningitis
Seele, J. and Tauber, S.C. and Bunkowski, S. and Baums, C.G. and Valentin-Weigand, P. and de Buhr, N. and Beineke, A. and Iliev, A.I. and Brück, W. and Nau, R., BMC Infectious Diseases (2018) | Artikel
Missing elimination via membrane vesicle shedding contributes to the diminished calcium sensitivity of listeriolysin O
Maurer, J. and Hupp, S. and Pillich, H. and Mitchell, T.J. and Chakraborty, T. and Iliev, A.I., Scientific Reports (2018) | Artikel
Distinct neurotoxicity profile of listeriolysin O from listeria monocytogenes
Maurer, J. and Hupp, S. and Bischoff, C. and Foertsch, C. and Mitchell, T.J. and Chakraborty, T. and Iliev, A.I., Toxins (2017) | Artikel
Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation
Hupp, S. and Ribes, S. and Seele, J. and Bischoff, C. and Förtsch, C. and Maier, E. and Benz, R. and Mitchell, T.J. and Nau, R. and Iliev, A.I., British Journal of Pharmacology (2017) | Artikel
Direct transmembrane interaction between actin and the pore-competent, cholesterol-dependent cytolysin pneumolysin
Hupp, S. and Förtsch, C. and Wippel, C. and Ma, J. and Mitchell, T.J. and Iliev, A.I., Journal of Molecular Biology (2013) | Artikel
Bacterial Cytolysin during Meningitis Disrupts the Regulation of Glutamate in the Brain, Leading to Synaptic Damage
Wippel, C. and Maurer, J. and Förtsch, C. and Hupp, S. and Bohl, A. and Ma, J. and Mitchell, T.J. and Bunkowski, S. and Brück, W. and Nau, R. and Iliev, A.I., PLoS Pathogens (2013) | Artikel
Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from Streptococcus pneumoniae in brain tissue
Wippel, C. and Förtsch, C. and Hupp, S. and Maier, E. and Benz, R. and Ma, J. and Mitchell, T.J. and Iliev, A.I., Journal of Infectious Diseases (2011) | Artikel
Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity
Förtsch, C. and Hupp, S. and Ma, J. and Mitchell, T.J. and Maier, E. and Benz, R. and Iliev, A.I., Toxins (2011) | Artikel
Quantitative fluorescence microscopy techniques.
Esposito, A. and Schlachter, S. and Schierle, G.S. and Elder, A.D. and Diaspro, A. and Wouters, F.S. and Kaminski, C.F. and Iliev, A.I., Methods in molecular biology (Clifton, N.J.) (2009) | Artikel
Rapid microtubule bundling and stabilization by the Streptococcus pneumoniae neurotoxin pneumolysin in a cholesterol-dependent, non-lytic and Src-kinase dependent manner inhibits intracellular trafficking
Iliev, A.I. and Djannatian, J.R. and Opazo, F. and Gerber, J. and Nau, R. and Mitchell, T.J. and Wouters, F.S., Molecular Microbiology (2009) | Artikel
Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures
Lotz, M. and Ebert, S. and Esselmann, H. and Iliev, A.I. and Prinz, M. and Wiazewicz, N. and Wiltfang, J. and Gerber, J. and Nau, R., Journal of Neurochemistry (2005) | Artikel
Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide
Stagi, M. and Dittrich, P.S. and Frank, N. and Iliev, A.I. and Schwille, P. and Neumann, H., Journal of Neuroscience (2005) | Artikel
