Biografie

'SEFAGIA
WIA
LS2

Forschung und Publikationen

• Publications
  157 Publikationen

  Autophagy and mitophagy at the synapse and beyond: implications for learning, memory and neurological disorders
  Autophagy (2026) | Artikel

  Deferiprone protects against photoreceptor degeneration by inhibiting parthanatos
  Cell Death & Disease (2025) | Artikel

  Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy
  Autophagy (2025) | Artikel

  Women in Autophagy: an initiative to promote gender parity in science
  Nature Cell Biology (2024) | Artikel

  Recycling the recyclers: lysophagy emerges as a new pharmacological target for retinal degeneration
  Autophagy (2024) | Artikel

  Aging STINGs: mitophagy at the crossroads of neuroinflammation
  Autophagy (2024) | Artikel

  Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy
  Alexandre Leytens, Rocio BENITEZ FERNANDEZ, Carlos JIMENEZ GARCIA, Carole ROUBATY, Michael Stumpe, Patricia BOYA, Joern Dengjel, Rocío Benítez-Fernández, Carlos Jiménez-García, Carole Roubaty, Patricia Boya, Jörn Dengjel, (2024) | Preprint

  Faire le ménage dans nos cellules pour prolonger la santé physique , in La Liberté 7 mars 2024
  Alt, Rémi (3.2024) | Presseartikel

  Mitophagy curtails cytosolic mtDNA-dependent activation of cGAS/STING inflammation during aging
  Nature Communications (2024) | Artikel

  Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents
  Journal of Enzyme Inhibition and Medicinal Chemistry (2023) | Artikel

  Mitophagy in the retina: Viewing mitochondrial homeostasis through a new lens
  Progress in Retinal and Eye Research (2023) | Artikel

  Carbon Monoxide Stimulates Both Mitophagy And Mitochondrial Biogenesis to Mediate Protection Against Oxidative Stress in Astrocytes
  Molecular Neurobiology (2023) | Artikel

  La saveur, toute une pizza , in Universitas 02/2023
  Patricia, Boya (2.2023) | Presseartikel

  El objetivo del Silver Film festival es dar visibilidad a las personas mayores. Es su primera edición y está teniendo una gran acogida.
  RTVEPaisVasco , Twitter (2023) | Sonstiges

  Des goûts et des odeurs , in Universitas 02/2023
  Patricia, Michaud (2023) | Presseartikel

  The mechanism of macroautophagy: The movie
  Autophagy Reports (2022) | Artikel

  BNIP3L/NIX regulates both mitophagy and pexophagy
  The EMBO Journal (2022) | Artikel

  Discovery of Mitophagy Inhibitors with Therapeutic Potential in Different Familial Amyotrophic Lateral Sclerosis Mutations
  International Journal of Molecular Sciences (2022) | Artikel

  Apoptosis-Inducing Factor Deficiency Induces Tissue-Specific Alterations in Autophagy: Insights from a Preclinical Model of Mitochondrial Disease and Exercise Training Effects
  Antioxidants (2022) | Artikel

  Autophagy induction during stem cell activation plays a key role in salivary gland self-renewal
  Autophagy (2022) | Artikel

  Investigación con ratones: por qué el sexo sí importa
  (2022) | Sonstiges

  Regulation of PRKN-independent mitophagy
  Autophagy (2022) | Artikel

  Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration
  Nature Communications (2022) | Artikel

  Ambra1 haploinsufficiency in CD1 mice results in metabolic alterations and exacerbates age-associated retinal degeneration
  Autophagy (2022) | Artikel

  p38 MAPK priming boosts VSMC proliferation and arteriogenesis by promoting PGC1α-dependent mitochondrial dynamics
  Scientific Reports (2022) | Artikel

  Autophagy in major human diseases
  The EMBO Journal (2021) | Artikel

  Lipid dismantling of lens organelles for clear vision
  Nature (2021) | Artikel

  Molecular Alterations in Sporadic and SOD1-ALS Immortalized Lymphocytes: Towards a Personalized Therapy
  International Journal of Molecular Sciences (2021) | Artikel

  HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice
  Cell Death and Differentiation (2021) | Artikel

  Autophagy and disease: new insights and challenges ahead
  Molecular Aspects of Medicine (2021) | Artikel

  Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹
  Autophagy (2021) | Artikel

  Phenotypic Assay Leads to Discovery of Mitophagy Inducers with Therapeutic Potential for Parkinson's Disease
  ACS Chemical Neuroscience (2021) | Artikel

  New insights into the role of autophagy in retinal and eye diseases
  Molecular Aspects of Medicine (2021) | Artikel

  Towards a better understanding of the neuro-developmental role of autophagy in sickness and in health
  Cell Stress (2021) | Artikel

  Caty Casas (1967-2020)
  Autophagy (2020) | Artikel

  Age related retinal Ganglion cell susceptibility in context of autophagy deficiency
  Cell Death Discovery (2020) | Artikel

  The mito-QC Reporter for Quantitative Mitophagy Assessment in Primary Retinal Ganglion Cells and Experimental Glaucoma Models
  International Journal of Molecular Sciences (2020) | Artikel

  Serum- and glucocorticoid-induced kinase 1, a new therapeutic target for autophagy modulation in chronic diseases
  Expert Opinion on Therapeutic Targets (2020) | Artikel

  HIF1α or mitophagy: Which drives cardiomyocyte differentiation?
  Cell Stress (2020) | Artikel

  A comparative map of macroautophagy and mitophagy in the vertebrate eye
  Autophagy (2019) | Artikel

  Immunological Synapse Formation Induces Mitochondrial Clustering and Mitophagy in Dendritic Cells
  The Journal of Immunology (2019) | Artikel

  Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy
  Autophagy (2019) | Artikel

  Lipotoxic Effects of Palmitic Acid on Astrocytes Are Associated with Autophagy Impairment
  Molecular Neurobiology (2019) | Artikel

  Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity
  Cell Metabolism (2019) | Artikel

  Erratum: Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity (Cell Metabolism (2019) 30(4) (754–767.e9), (S1550413119303833), (10.1016/j.cmet.2019.07.010))
  Cell Metabolism (2019) | Artikel

  Lysosomal membrane permeabilization and cell death
  Traffic (2018) | Artikel

  BNIP3L/NIX-dependent mitophagy regulates cell differentiation via metabolic reprogramming
  Autophagy (2018) | Artikel

  Lysosome-dependent cell death and deregulated autophagy induced by amine-modified polystyrene nanoparticles
  Open Biology (2018) | Artikel

  Autophagy in stem cells: repair, remodelling and metabolic reprogramming
  Development (2018) | Artikel

  Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
  Cell Death and Differentiation (2018) | Artikel

  Lysosomal membrane permeabilization as a cell death mechanism in cancer cells
  Biochemical Society Transactions (2018) | Artikel

  Mitophagy, metabolism, and cell fate
  Molecular & Cellular Oncology (2017) | Artikel

  Molecular definitions of autophagy and related processes
  The EMBO Journal (2017) | Artikel

  Why autophagy is good for retinal ganglion cells?
  Eye (2017) | Artikel

  Autophagy and vision
  Medecine Sciences: M/S (2017) | Artikel

  Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens
  Cell Death and Disease (2017) | Artikel

  Programmed mitophagy is essential for the glycolytic switch during cell differentiation
  The EMBO Journal (2017) | Artikel

  Cytofluorometric Assessment of Mitophagic Flux in Mammalian Cells and Tissues
  Methods in Enzymology (2017) | Artikel

  Standard Assays for the Study of Autophagy in the Ex Vivo Retina
  Cells (2017) | Artikel

  The S1P1 receptor-selective agonist CYM-5442 protects retinal ganglion cells in endothelin-1 induced retinal ganglion cell loss
  Experimental Eye Research (2017) | Artikel

  Autofagia: cómo nuestras células se reciclan
  Boya, Patricia (2017) | Presseartikel

  Lysosomal membrane permeabilization in cell death: new evidence and implications for health and disease
  Targeting the Lysosome (2016) | Artikel

  Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
  Autophagy (2016) | Artikel

  Lysosomal cell death mechanisms in aging
  Ageing Research Reviews (2016) | Artikel

  Autophagy in the eye: Development, degeneration, and aging
  Progress in Retinal and Eye Research (2016) | Artikel

  Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
  Autophagy (2016) | Artikel

  Altered Blood Gene Expression of Tumor-Related Genes (PRKCB, BECN1, and CDKN2A) in Alzheimer's Disease
  Molecular Neurobiology (2016) | Artikel

  Visual decline in aged mice is delayed by proinsulin
  Investigative Ophthalmology & Visual Science (2016) | Artikel

  Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids
  Oncotarget (2016) | Artikel

  VASCULAR BIOLOGY I. MITOPHAGY ACTS AS A SAFEGUARD MECHANISM AGAINST HUMAN VASCULAR SMOOTH MUSCLE CELL APOPTOSIS INDUCED BY ATHEROGENIC LIPIDS
  Atherosclerosis (2016) | Artikel

  Autophagy: The system of recycling and cellular defense which have all our cells,Autofagia: El sistema de reciclaje y defensa celular que tienen todas nuestras células
  Anales de la Real Academia Nacional de Farmacia (2016) | Artikel

  Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
  Autophagy (2016) | Artikel

  Why is autophagy essential to keep our cells healthy? ¿Por qué la autofagia es esencial para mantener nuestras células sanas? , in calameo.com
  (2016) | Presseartikel

  Lysosomal membrane permeabilization and autophagy blockade contribute to photoreceptor cell death in a mouse model of retinitis pigmentosa
  Investigative Ophthalmology & Visual Science (2015) | Artikel

  New method to assess mitophagy flux by flow cytometry
  Autophagy (2015) | Artikel

  Autophagic flux determination in vivo and ex vivo
  Methods (2015) | Artikel

  Mitophagy in mitosis: More than a myth
  Autophagy (2015) | Artikel

  AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest
  Nature Cell Biology (2015) | Artikel

  Autophagy researchers.
  Autophagy (2014) | Artikel

  High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A
  Cell Death and Differentiation (2014) | Artikel

  Reduced autophagy in skin aging and positive regulation by a saponin-rich asparagus extract
  Journal of Investigative Dermatology (2014) | Artikel

  Autophagy in retina and axonal degeneration
  Acta Ophthalmologica (2014) | Artikel

  Balance between autophagic pathways preserves retinal homeostasis
  Aging Cell (2013) | Artikel

  CELL BIOLOGY Recycling in sight
  Nature (2013) | Artikel

  Emerging regulation and functions of autophagy
  Nature Cell Biology (2013) | Artikel

  Emerging regulation and functions of autophagy (vol 15, pg 713, 2013)
  Nature Cell Biology (2013) | Artikel

  Interactions between autophagic and endo-lysosomal markers in endothelial cells
  Histochemistry and Cell Biology (2013) | Artikel

  Time resolved study of cell death mechanisms induced by amine-modified polystyrene nanoparticles
  Nanoscale (2013) | Artikel

  Autophagy disregulation in the retina during aging and neurodegeneration
  Investigative Ophthalmology & Visual Science (2013) | Artikel

  Cell biology: Recycling in sight
  Nature (2013) | Artikel

  Emerging regulation and functions of autophagy
  Nature Cell Biology (2013) | Artikel

  Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells
  Autophagy (2012) | Artikel

  Autophagy disregulation in the retina: neurodegeneration and aging
  Febs Journal (2012) | Artikel

  Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice
  Cell Death and Differentiation (2012) | Artikel

  Axonal damage, autophagy and neuronal survival
  Autophagy (2012) | Artikel

  Guidelines for the use and interpretation of assays for monitoring autophagy
  Autophagy (2012) | Artikel

  Lysosomal Function and Dysfunction: Mechanism and Disease
  Antioxidants & Redox Signaling (2012) | Artikel

  Micronucleophagy: A new mechanism to protect against chromosomal instability?
  Cell Cycle (2012) | Artikel

  Role of autophagy during the development of the vertebrate nervous system
  Febs Journal (2012) | Artikel

  AUTOPHAGY IN THE RETINA: DEVELOPMENT, PHYSIOLOGY AND PATHOLOGY
  Autophagy of the Nervous System: Cellular Self-digestion in Neurons and Neurological Diseases (2012) | Artikel

  Lysosomal membrane permeabilization in Parkinson disease
  Autophagy (2011) | Artikel

  Impaired autophagy in Lafora disease
  Autophagy (2010) | Artikel

  Intracellular Silicon Chips in Living Cells
  Small (2010) | Artikel

  Laforin, the most common protein mutated in Lafora disease, regulates autophagy
  Human Molecular Genetics (2010) | Artikel

  Pathogenic Lysosomal Depletion in Parkinson's Disease
  Journal of Neuroscience (2010) | Artikel

  Structural Determinants Allowing Endolysosomal Sorting and Degradation of Endosomal GTPases
  Traffic (2010) | Artikel

  The nuclear cofactor DOR regulates autophagy in mammalian and Drosophila cells
  Embo Reports (2010) | Artikel

  Tumor suppressor p27(Kip1) undergoes endolysosomal degradation through its interaction with sorting nexin 6
  Faseb Journal (2010) | Artikel

  Autophagy is not universally required for phosphatidyl-serine exposure and apoptotic cell engulfment during neural development
  Autophagy (2009) | Artikel

  Beclin 1: a BH3-only protein that fails to induce apoptosis
  Oncogene (2009) | Artikel

  Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
  Journal of Clinical Investigation (2009) | Artikel

  Early neural cell death: numbers and cues from the developing neuroretina
  International Journal of Developmental Biology (2009) | Artikel

  The C-Terminal Sequence of RhoB Directs Protein Degradation through an Endo-Lysosomal Pathway
  Plos One (2009) | Artikel

  TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action
  Autophagy (2009) | Artikel

  Single cell biomolecular recognition by silicon intracelullar chips
  Duch, M. and Vázquez, P. and Gómez-Martínez, R. and Boya, P. and Muriano, A. and Pinacho, D. and Sanvicens, N. and Sánchez-Baeza, F. and De La Rosa, E. and Esteve, J. and Suárez, T. and Plaza, J.A., Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences: (2009) | Konferenz

  Autophagy is not universally required for phosphatidyl-serine exposure and apoptotic cell engulfment during neural development
  Autophagy (2009) | Artikel

  TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action
  Autophagy (2009) | Artikel

  Attenuation of vision loss and delay in apoptosis of photoreceptors induced by proinsulin in a mouse model of retinitis pigmentosa
  Investigative Ophthalmology & Visual Science (2008) | Artikel

  How autophagy is related to programmed cell death during the development of the nervous system
  Biochemical Society Transactions (2008) | Artikel

  Intra-mitochondrial degradation of Tim23 curtails the survival of cells rescued from apoptosis by caspase inhibitors
  Cell Death and Differentiation (2008) | Artikel

  Lysosomal membrane permeabilization in cell death
  Oncogene (2008) | Artikel

  The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium
  Cell Death and Differentiation (2008) | Artikel

  Early neural cell death: An overlooked process in neural development
  Anales de la Real Academia Nacional de Farmacia (2007) | Artikel

  Early neural cell death: an overlooked process in neural development
  (2007) | Artikel

  Youth and the future of science
  Boletín de la Sociedad Española de Bioquímica y Biología Molecular (2006) | Artikel

  ESOF, an initiative to bring science closer to society
  Boletín de la Sociedad Española de Bioquímica y Biología Molecular (2006) | Artikel

  Cell death in early neural life.
  Birth defects research. Part C, Embryo today : reviews (2005) | Artikel

  Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope
  Journal of Experimental Medicine (2005) | Artikel

  Inhibition of macroautophagy triggers apoptosis
  Molecular and Cellular Biology (2005) | Artikel

  The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death
  Journal of Cell Science (2005) | Artikel

  An anti-apoptotic viral protein that recruits bax to mitochondria
  Journal of Biological Chemistry (2004) | Artikel

  An anti-apoptotic viral protein that recruits Bax to mitochondria
  Biochimica Et Biophysica Acta-Bioenergetics (2004) | Artikel

  Anti-apoptotic activity of the glutathione peroxidase homologue encoded by HIV-1
  Apoptosis (2004) | Artikel

  Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma
  Apoptosis (2004) | Artikel

  NF-kappa B and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope
  Journal of Experimental Medicine (2004) | Artikel

  Viral proteins targeting mitochondria: controlling cell death
  Biochimica Et Biophysica Acta-Bioenergetics (2004) | Artikel

  A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine induced liver damage: A possible mechanism for viral persistence
  Journal of Hepatology (2003) | Artikel

  A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine-induced liver damage
  Hepatology (2003) | Artikel

  Bcl-2 and CCND1/CDK4 as molecular markers of the cellular effects of mTOR inhibitors in human ovarian carcinoma cells
  Clinical Cancer Research (2003) | Artikel

  Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization
  Apoptosis (2003) | Artikel

  Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
  Journal of Experimental Medicine (2003) | Artikel

  Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
  Oncogene (2003) | Artikel

  Mitochondrion-targeted apoptosis regulators of viral origin
  Biochemical and Biophysical Research Communications (2003) | Artikel

  The chemopreventive agent N-(4-hydroxyphenyl) retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family
  Oncogene (2003) | Artikel

  Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and BCI-X-L
  Oncogene (2002) | Artikel

  Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-X(L).
  Oncogene (2002) | Artikel

  Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization
  Cell Death and Differentiation (2002) | Artikel

  Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo
  Apoptosis (2002) | Artikel

  The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway
  Cell Death and Differentiation (2002) | Artikel

  Stat-1 and IRF-1: two factors in the signaling pathway of interferons related to viral load and liver damage in chronic hepatitis C (CH-C)
  Journal of Hepatology (2002) | Artikel

  Expression of interferon-alpha subtypes in peripheral mononuclear cells from patients with chronic hepatitis C: a role for interferon-alpha 5
  Journal of Viral Hepatitis (2001) | Artikel

  Nuclear factor-kappa B in the liver of patients with chronic hepatitis C: Decreased RelA expression is associated with enhanced fibrosis progression
  Hepatology (2001) | Artikel

  Viral and bacterial proteins regulating apoptosis at the mitochondrial level
  Embo Journal (2001) | Artikel

  Antioxidant status and glutathione metabolism in peripheral blood mononuclear cells from patients with chronic hepatitis C
  Journal of Hepatology (1999) | Artikel

  Interferon alfa subtypes and levels of type I interferons in the liver and peripheral mononuclear cells in patients with chronic hepatitis C and controls
  Hepatology (1999) | Artikel

  VIROIDS AND VIRUSES AT THE ORIGIN OF ORGANIZED LIFE
  CHEMICAL EVOLUTION: ORIGIN OF LIFE (1993) | Artikel

  A proteinaceus sequence for endo-lysosomal localization and degradation.
  Patricia Boya | Sonstiges

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