Mitochondria-Lysosome Crosstalk Shapes Metabolic Transition in Neonatal Enterocytes
Ian G Ganley, Tamara González, María Velasco de la Esperanza, Covadonga Díaz-Díaz, Nuria Martínez-Martín, Fernando Martín-Belmonte, Marta Iborra-Pernichi, Patricia Boya, Covadonga Diaz-Diaz, Nuria Martinez-Martin, Tamara Gonzalez, Alejandra Ramos-Manzano, Gonzalo Herranz, Sara Cogliati, Fernando Martin-Belmonte, Laura Akintche, Maria Velasco de la Esperanza, Ian Ganley, Diego Alonso-Larre, (2025) | Preprint
Deferiprone protects against photoreceptor degeneration by inhibiting parthanatos
Cell Death & Disease (2025) | Artikel
The developing retina undergoes mitochondrial remodeling via PINK1/PRKN-dependent mitophagy
Michael Stumpe, Juan Zapata-Munoz, Juan Ignacio Jimenez-Loygorri, Beatriz VILLAREJO ZORI, Patricia Boya, Sandra Alonso-Gil, Petra Teresak, Benan J Mathai, Ian G Ganley, Anne Simonsen, Joern Dengjel, (2025) | Preprint
Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy
Autophagy (2025) | Artikel
Women in Autophagy: an initiative to promote gender parity in science
Nature Cell Biology (2024) | Artikel
Recycling the recyclers: lysophagy emerges as a new pharmacological target for retinal degeneration
Autophagy (2024) | Artikel
Aging STINGs: mitophagy at the crossroads of neuroinflammation
Autophagy (2024) | Artikel
Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy
Alexandre Leytens, Rocio BENITEZ FERNANDEZ, Carlos JIMENEZ GARCIA, Carole ROUBATY, Michael Stumpe, Patricia BOYA, Joern Dengjel, Patricia Boya, Rocío Benítez-Fernández, Carlos Jiménez-García, Carole Roubaty, Jörn Dengjel, (2024) | Preprint
Mitophagy curtails cytosolic mtDNA-dependent activation of cGAS/STING inflammation during aging
Nature Communications (2024) | Artikel
Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents
Journal of Enzyme Inhibition and Medicinal Chemistry (2023) | Artikel
Ambra1 haploinsufficiency results in metabolic alterations and exacerbates age-associated retinal degeneration
Ramírez-Pardo, I. and Villarejo-Zori, B. and Jiménez-Loygorri, J.I. and Sierra-Filardi, E. and Alonso-Gil, S. and Mariño, G. and de la Villa, P. and Fitze, P.S. and Fuentes, J.M. and García-Escudero, R. and Gomez-Sintes, R. and Boya, P.
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Discovery of mitophagy inhibitors with therapeutic potential in different familiar Amyotrophic Lateral Sclerosis mutations
Maestro, I. and de la Ballina, L.R. and Porras, G. and Corrochano, S. and de Lago, E. and Simonsen, A. and Boya, P. and Martinez, A.
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p38 MAPK priming boosts VSMC proliferation and arteriogenesis by promoting PGC1α-dependent mitochondrial dynamics
Scientific Reports (2022) | Artikel
Autophagy in major human diseases
The EMBO Journal (2021) | Artikel
Lipid dismantling of lens organelles for clear vision
Nature (2021) | Artikel
Molecular Alterations in Sporadic and SOD1-ALS Immortalized Lymphocytes: Towards a Personalized Therapy
International Journal of Molecular Sciences (2021) | Artikel
HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice
Cell Death and Differentiation (2021) | Artikel
Autophagy and disease: new insights and challenges ahead
Molecular Aspects of Medicine (2021) | Artikel
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy (2021) | Artikel
Phenotypic Assay Leads to Discovery of Mitophagy Inducers with Therapeutic Potential for Parkinson's Disease
ACS Chemical Neuroscience (2021) | Artikel
New insights into the role of autophagy in retinal and eye diseases
Molecular Aspects of Medicine (2021) | Artikel
Towards a better understanding of the neuro-developmental role of autophagy in sickness and in health
Cell Stress (2021) | Artikel
Microglial phagocytosis dysfunction during stroke is prevented by rapamycin
Beccari, S. and Sierra-Torre, V. and Valero, J. and García-Zaballa, M. and Carretero-Guillen, A. and Capetillo-Zarate, E. and Domercq, M. and Huguet, P.R. and Ramonet, D. and Osman, A. and Han, W. and Dominguez, C. and Faust, T.E. and Touzani, O. and Boya, P. and Schafer, D. and Mariño, G. and Canet-Soulas, E. and Blomgren, K. and Plaza-Zabala, A. and Sierra, A.
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Caty Casas (1967-2020)
Autophagy (2020) | Artikel
Age related retinal Ganglion cell susceptibility in context of autophagy deficiency
Cell Death Discovery (2020) | Artikel
The mito-QC Reporter for Quantitative Mitophagy Assessment in Primary Retinal Ganglion Cells and Experimental Glaucoma Models
International Journal of Molecular Sciences (2020) | Artikel
Serum- and glucocorticoid-induced kinase 1, a new therapeutic target for autophagy modulation in chronic diseases
Expert Opinion on Therapeutic Targets (2020) | Artikel
HIF1α or mitophagy: Which drives cardiomyocyte differentiation?
Cell Stress (2020) | Artikel
A comparative map of macroautophagy and mitophagy in the vertebrate eye
Autophagy (2019) | Artikel
Immunological Synapse Formation Induces Mitochondrial Clustering and Mitophagy in Dendritic Cells
The Journal of Immunology (2019) | Artikel
TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action
Autophagy (2009) | Artikel
Single cell biomolecular recognition by silicon intracelullar chips
Duch, M. and Vázquez, P. and Gómez-Martínez, R. and Boya, P. and Muriano, A. and Pinacho, D. and Sanvicens, N. and Sánchez-Baeza, F. and De La Rosa, E. and Esteve, J. and Suárez, T. and Plaza, J.A.,
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Autophagy is not universally required for phosphatidyl-serine exposure and apoptotic cell engulfment during neural development
Autophagy (2009) | Artikel
TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action
Autophagy (2009) | Artikel
Attenuation of vision loss and delay in apoptosis of photoreceptors induced by proinsulin in a mouse model of retinitis pigmentosa
Investigative Ophthalmology & Visual Science (2008) | Artikel
How autophagy is related to programmed cell death during the development of the nervous system
Biochemical Society Transactions (2008) | Artikel
Intra-mitochondrial degradation of Tim23 curtails the survival of cells rescued from apoptosis by caspase inhibitors
Cell Death and Differentiation (2008) | Artikel
Lysosomal membrane permeabilization in cell death
Oncogene (2008) | Artikel
The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium
Cell Death and Differentiation (2008) | Artikel
Early neural cell death: an overlooked process in neural development
Anales De La Real Academia Nacional De Farmacia (2007) | Artikel
