Offene Stellen

  • Senior Scientist or Advanced Clinician Scientist (100%)

    The position is open at Division of Endocrinology of the Section of Medicine of the University of Fribourg, Switzerland, to study the molecular mechanisms of sex development in humans (https://www.unifr.ch/med/de/research/groups/lauber/)


    Beginning : April, 01, 2022
    Duration : 3-4 years
    Location: Université de Fribourg
    Working time: 100%

     

    Objective

    The main objective of our work is the elucidation of the molecular basis of human sex development to better define phenotypes and therapies of its complex defects.

    Goals

    1. Gain new insights in sex differentiation in humans.
    2. Create new models for understanding mechanism of disease.

    Technically, the focus of the work will be to

    a) create human male and female gonadal cells from inducible pluripotent stem cells directly from patients affected by differences of sex development to study the mechanisms that lead to disease.

    b) use the fruit fly drosophila melanogaster as an animal model to study the functional consequences of unknown variants found in patients with differences of sex development.

    We will also employ standard cell and molecular biology, genetics, biochemistry, exome and RNA-sequencing, CRISP-Cas9 gene editing and mass spectrometry techniques. Bioinformatic analysis of next generation sequencing data and 3D-modeling is also one of our expertise.

    Your profile

    • A PhD, MD or equivalent degree(s) are required.
    • Knowledge and experience in molecular and cell biology are mandatory. Knowledge and/or prior experience in stem cells, cell therapy and/or gene engineering are a plus.
    • Knowledge and/or prior experience in Drosophila melanogaster handling is desirable.
    • Knowledge of the German or the French language is of advantage
    • Successful candidates will be independent, creative and enthusiastic researchers, capable of working efficiently in an international team of other postdoctoral fellows and PhD students. Outstanding laboratory capabilities and strong organizational skills to support Bachelor, Master and PhD students as well as Post Docs are expected.
    • Candidates have to present a successful academic track record

    We look forward to receiving your application with the following documents

    • Cover letter with statement of interest
    • CV
    • If applicable: brief summary on the envisioned independent research
    • Diplomas and course transcripts
    • Contact details of three referees

    Contact

    Anna Lauber-Biason, M.D.
    Chair of Endocrinology
    University of Fribourg
    Section of Medicine, Faculty of Science and Medicine
    Chemin du Musée 5
    1700 Fribourg
    E-mail. anna.lauber@unifr.ch

     

    The University of Fribourg is Switzerland’s only bilingual university, offering a full academic curriculum both in French and German. A number of Master programmes are taught in English and the University offers a wide range of opportunities for PhD and doctoral studies as well as international Exchange and Summer School Programmes.

    The University of Fribourg places scientific research that is closely linked to academic teaching at the heart of its activities. With an array of centres of scientific excellence as well as research programmes across the entire disciplinary spectrum, we aim to extend the frontiers of scientific knowledge to help solve mankind’s current and future challenges. https://www.unifr.ch/home/en/

     
  • SNF Doktoranden-Stelle in der Abteilung „Systems Neuroscience“ (80%)

    Die Abteilung Systems Neuroscience an der Fakultät für Medizin und Naturwissenschaften der Universität Freiburg,  sucht zum nächstmöglichen Beginn eine/n Doktorandin/en. Er / sie soll in Zusammenarbeit mit der Arbeitsgruppe an der Entwicklung einer kortikalen visuellen Prothese in einem Tiermodell zur Blindheit arbeiten. Das Projekt ist vom SNF gefördert. Weitere Informationen zur Arbeitsgruppe und zum Projekt.

    Anforderungsprofil:

    • Sehr guter Masterabschluss in Psychologie, Naturwissenschaften oder Life
      Sciences
    • Sehr gute analytische und statistische Kenntnisse, v.a. in Matlab
    • Freude an der Arbeit mit Tieren
    • Sehr gute Englischkenntnisse, darüber hinaus sind Deutsch- und vor allem
      Französischkenntnisse von Vorteil
    • Sehr hohes persönliches Commitment

    Was bieten wir?

    • International anerkannte Forschungsexpertise im Bereich Optogenetik und
      Elektrophysiologie
    • Einbindung und Zusammenarbeit in ein produktives, internationales Team
    • Kontaktmöglichkeiten zu renommierten internationalen Wissenschaftlern/-
      innen
    • Enge Zusammenarbeit mit dem Lehrstuhlinhaber
    • Hervorragende Weiterbildungsmöglichkeiten

    Die Bewerbungsunterlagen (CV, Zeugnisse sowie ein Motivationsschreiben, in dem Sie auf max. zwei Seiten erläutern, warum Sie sich mit dem Forschungsthema beschäftigen möchten; Masterarbeit) sind in einem PDF-File per Email zu richten an: Prof. Dr. Michael C. Schmid, michael.schmid@unifr.ch. Bewerbungen werden gesichtet, bis die Stelle besetzt ist. Die Universität Freiburg fördert eine ausgewogene Vertretung von Frauen und Männern. Frauen werden ausdrücklich aufgefordert, sich zu bewerben. Die Bewerbungsfrist läuft bis am 15.04.2022.

  • Allrounder, Allrounderin für den Bereich IT-Support 80-100 %

    Die Abteilung Medizin der Universität Freiburg steht für praxisnahe, interdisziplinäre und vielseitige Aus- und Weiterbildungen. Sie beschäftigt 276 Mitarbeitende.
    Der Informatikdienst der Abteilung Medizin (MED-IT) ist verantwortlich für den Betrieb und den Unterhalt der Fachanwendungen in den Bereichen Administration, Unterricht und Forschung. Er stellt eine professionelle Inbetriebnahme, Sicherung und Anpassung der benötigten Funktionalität und die notwendige Weiterentwicklung der Fachanwendungen sicher.
    Unsere Hauptstandorte sind auf dem Plateau de Pérolles und Arsenaux. Wir betreuen aber auch unsere Mitarbeitenden der Universität Freiburg, welche im Kantonsspital Freiburg (HFR), dem Freiburger Netzwerk für psychische Gesundheit (RFSM) arbeiten.
    Um das MED-IT zu vervollständigen, suchen wir Sie und Ihr Talent als ...

    Anforderungen
    • Sie stellen bereit, installieren und unterhalten Hardware-, Software- und Netzwerkkomponenten bei Administrations-, Forschungs- und Peripheriegeräten
    • Sie lokalisieren und lösen selbstständig Hardware-, Software- und Netzwerkprobleme
    • Sie koordinieren bei grössere Störungen und Problemen mit den internen Partnern
    • Sie schulen und unterstützen Mitarbeitende im Umgang mit der IT-Infrastruktur
    • Sie verwalten und administrieren die Hard- und Software
    • Sie pflegen und unterhalten die Webseiten der Abteilung Medizin,
    • Sie helfen beim Unterhalt, der Entwicklung und dem Einsatz der Computersysteme zur Unterstützung der Lehre (LMS, CMS, CBA)
    • Sie aktualisieren die Benutzerdokumentation und die Umsetzungsrichtlinien

    Ihre Kompetenzen

    • Sie haben eine abgeschlossene technische Berufsausbildung mit einer Weiterbildung im Bereich IT-Support (z.B. System- und Netzwerktechniker/in, ICT-Professional SIZ) und/oder langjährige Erfahrung in diesem Bereich
    • Sie bringen eine Mehrjährige 2nd Level Support Erfahrung mit
    • Sie sind flexibel, teamfähig, kundenorientiert und belastbar
    • Sie haben sehr gute Kenntnisse von Windows 10, Mac OSX und MS Office
    • Sie haben Kenntnisse und Berufserfahrung mit Tools wie Moodle, Produkten von Switch
    • Sie habe sehr gute Deutsch- und Französischkenntnisse in Wort und Schrift, sowie gute Englisch-Kenntnisse

    Beginn: Ab 1. Juli 2022 oder nach Vereinbarung
    Art der Anstellung: Unbefristet
    Kontakt: Helene Wigginton, 026 300 8161, helene.wigginton@unifr.ch

  • Post-doctoral position in Sensorimotor Neuroscience

    THE LAB
    The group of Mario Prsa at the University of Fribourg (prsalab.org) is looking for post-doctoral candidates to conduct research on neural mechanisms of forelimb sensorimotor adaptation and/or proprioceptive sensory processing.
    Our laboratory is part of the Department of Neuroscience and Movement Science within the Faculty of Medicine at the University of Fribourg comprised of a vibrant scientific community including more than 20 multi-disciplinary research groups.

    RESEARCH
    Movements are at the center of all our behavior and accurate movements allow us to properly interact with the world. Proprioception and sensorimotor adaptation are two physiological processes crucial for maintaining movement accuracy. The applicant will use state-of-the art behavioral, optogenetic, two-photon microscopy and neuroanatomical tracing techniques to dissect the underlying neuronal circuits in the mouse brain.

    YOUR PROFILE

    •  PhD degree in Systems Neuroscience (or related discipline)
    • Highly motivated, excellent analytical, experimental and writing skills.
    • Expertise in rodent behavior, optogenetics, in-vivo imaging and/or neuroanatomical tracing is highly
      desirable.
    • Proficiency in data analysis, hardware programming and experimental control with Matlab is
      preferred.

    THE POSITION
    We offer a fully funded post-doctoral position (1 year initial contract) planned to start in September 2022 (or earlier). Interested applicants should send a letter of motivation, complete CV and a list of referees to mario.prsa@unifr.ch.

  • Postdoctoral Position in Cancer Research 80-100%

     A 80-100% post doc position is available to study the effect of breast cancer progression and dormancy on the local and systemic immune/inflammatory responses using established in vivo models of dormancy, escape and metastasis, flow cytometry, immunohistology and transcriptmics analyses, and ex vivo co-culture models. Technical assistants will be available. Collaborations with bioinformatics, modeling and clinical transcriptomics groups. The position is available on an FNS funded project starting May 2022 for 2 years or longer.
    Lab description

    Requirements

    • PhD or MD/PhD with strong background in cancer biology and immunology
    • Experience with in vivo cancer models (mice)
    • Proficiency in FACS, RNASeq and bioinformatics analyses
    • Publications in the field
    • Motivation to independently thriving a project and establish collaborations
    • Command of written and spoken English

    We offer

    • Attractive and friendly working environment
    • Opportunity to actively lead and shape the development of the project
    • Possibility of teaching or coaching students

    Interested candidates should send the following documents in PDF format:

    • Motivation letter highlighting your background, interest in our research, and your career plan
    • Curriculum vitae, publication list and copies of certificates (MSC, MD, MD-PhD, PhD)
    • Contacts of two references

    Start: May 1st or upon agreement
    Send applications or queries to:
    Prof. Curzio Rüegg, curzio.ruegg@unifr.ch, copy to: Mrs Marie Tamm, marie.tamm@unifr.ch

  • Senior scientist at the Department of Medicine, Chair of Psychiatry and Psychotherapy 35%

    As senior scientist at Fribourg University, you will be joining a team of scientists and clinicians of the Psychiatry Research department, which is associated with the Psychiatry Hospital of the Canton of Fribourg in Villars-sur-Glâne (neighborhood of the city of Fribourg).

     

    The Chair of Psychiatry and Psychotherapy is building and expanding a multidisciplinary research program focusing on pharmacological, genetic/epigenetic and eHealth studies. The team has important collaborations with ETH Zurich und University Hospital Zurich in the field of molecular imaging.

     

    The successful applicant will have numerous opportunities to grow and expand his/her clinical, conceptual and methodological horizons. She/he will have access to imaging-epidemiological data, epigenetic and eHealth data.

     

    Responsibilities:

     

    - Methodological support for the research team
    - Coordination of an eHealth study
    - Critically analyze and evaluate data
    - Perform administrative tasks as assigned
    - Participate in student training
    - Writing of reports, papers and grant applications

     

    Qualification:

     

    - PhD or MD degree
    - Publication record in areas related to the responsibilities
    - Expertise in genetics and epigenetics would be a plus
    - Expertise in advanced imaging data analyses (e.g. connectivity analyses) would be a plus
    - Experience in analyzing eHealth data would be a plus
    - Strong English language skills are mandatory, German and French is a plus
    - Candidate must be able to work independently and, in a team, setting as well.

     

    The position is available from June 1st, 2022 or to be agreed upon a later date. Please send your complete application documents (CV, publication list, motivation letter, certificates as well as the names and email addresses of three referees) to:
    Prof. Dr. med. Gregor Hasler at gregor.hasler@unifr.ch

     

    Dead-line for application : May 27th, 2022

  • INTERSHIP POSITION : Minimum 6 month

    The IC Stoke Team is looking for a student to collaborate on their research projects in Switzerland.

    The student will have the opportunity to work in an international and highly motivating environment. The project involves the development of a new model of subcortical stroke in non-human primates and of cortico-spinal rehabilitation technologies for the recovery of arm and hand movements.

    The student will help with the management and setup of behavioral tasks, and participate to scientific discussions and data analysis.

    Prerequisites

    • Knowledge in English
    • Basic Knowledge in Matlab
    • Positive and pro-active attitude

    New Knowledge

    • Software: Vicon, Nexus, Matlab
    • Tasks: Kuka Robot, calibration, execution
    • Data analysis : Tracking, progam execution

    Interested persons lacking one or more of these requirements will be also considered according to the specific case.

    Contact
    Dr. Charles Latchoumane, latchoumane.c@gmail.com