Stein Group
Publications (peer-reviewed only)
Systematic Analysis of Immune Cell Motility Leveraging the Open Intravital Microscopy Database Immunemap
Pizzagalli, Diego Ulisse and Carrillo-Barberà, Pau and Bansal, Himanshu and Palladino, Elisa and Ceni, Kevin and Thelen, Benedikt and Pulfer, Alain and Moscatello, Enrico and Fiamma Cabini, Raffaella and Textor, Johannes and M N Wortel, Inge and Immunemap Consortium and Krause, Rolf and Fernandez Gonzalez, Santiago,
The EMBO journal
45.1
(2026), 334–348
| Article
Glia Modulates Immune Responses in the Retina Through Distinct MHC Pathways
Intonti, Simona and Kokona, Despina and Zinkernagel, Martin S. and Enzmann, Volker and Stein, Jens V. and Conedera, Federica M.,
Glia
73.4
(2025), 822–839
| Article
Macrophages Coordinate Immune Response to Laser-Induced Injury via Extracellular Traps
Conedera, Federica M. and Kokona, Despina and Zinkernagel, Martin S. and Stein, Jens V. and Lin, Charles P. and Alt, Clemens and Enzmann, Volker,
Journal of Neuroinflammation
21.1
(2024), 68
| Article
Exocrine Gland–Resident Memory CD8+ T Cells Use Mechanosensing for Tissue Surveillance
Ruef, Nora and Magdaleno, Jose Martínez and Ficht, Xenia and Purvanov, Vladimir and Palayret, Matthieu and Wissmann, Stefanie and Pfenninger, Petra and Stolp, Bettina and Thelen, Flavian and de Albuquerque, Juliana Barreto and Germann, Philipp and Sharpe, James and Abe, Jun and Legler, Daniel F. and Stein, Jens V.,
Science Immunology
8.90
(2023), eadd5724
| Article
Regulator of G-protein Signaling 1 Critically Supports CD8+ TRM Cell-Mediated Intestinal Immunity
von Werdt, Diego and Gungor, Bilgi and de Albuquerque, Juliana Barreto and Gruber, Thomas and Zysset, Daniel and Chung, Cheong K. C. Kwong and Corrêa-Ferreira, Antonia and Berchtold, Regina and Page, Nicolas and Schenk, Mirjam and Kehrl, John H. and Merkler, Doron and Imhof, Beat A. and Stein, Jens V. and Abe, Jun and Turchinovich, Gleb and Finke, Daniela and Hayday, Adrian C. and Corazza, Nadia and Mueller, Christoph,
Frontiers in Immunology
14
(2023), 1085895
| Article
Assessing the Role of T Cells in Response to Retinal Injury to Uncover New Therapeutic Targets for the Treatment of Retinal Degeneration
Conedera, Federica M. and Runnels, Judith M. and Stein, Jens V. and Alt, Clemens and Enzmann, Volker and Lin, Charles P.,
Journal of Neuroinflammation
20.1
(2023), 206
| Article
B Cell–Intrinsic Requirement for WNK1 Kinase in Antibody Responses in Mice
Hayward, Darryl A. and Vanes, Lesley and Wissmann, Stefanie and Sivapatham, Sujana and Hartweger, Harald and O'May, Joshua Biggs and de Boer, Leonard L. and Mitter, Richard and Köchl, Robert and Stein, Jens V. and Tybulewicz, Victor L.J.,
Journal of Experimental Medicine
220.3
(2023), e20211827
| Article
Dasatinib-Induced Spleen Contraction Leads to Transient Lymphocytosis
Marcos-Jiménez, Ana and Carvoeiro, Daniela Claudino and Ruef, Nora and Cuesta-Mateos, Carlos and Roy-Vallejo, Emilia and de Soria, Valle Gómez-García and Laganá, Claudio and del Campo, Lourdes and Zubiaur, Pablo and Villapalos-García, Gonzalo and Abad-Santos, Francisco and Stein, Jens V. and Muñoz-Calleja, Cecilia,
Blood Advances
7.11
(2023), 2418–2430
| Article
Editorial: The Cytoskeleton in T Cell Migration and Activation
Butte, Manish J. and Stein, Jens V. and Delon, Jérôme,
Frontiers in Immunology
13
(2022), 1057533
| Article
DOCK2 and Phosphoinositide-3 Kinase $\delta$ Mediate Two Complementary Signaling Pathways for CXCR5-dependent B Cell Migration
Wissmann, Stefanie and Stolp, Bettina and Jímenez, Ana Marcos and Stein, Jens V.,
Frontiers in Immunology
13
(2022), 982383
| Article
Microbial Uptake in Oral Mucosa–Draining Lymph Nodes Leads to Rapid Release of Cytotoxic CD8+ T Cells Lacking a Gut-Homing Phenotype
de Alburquerque, Juliana Barreto and Altenburger, Lukas M. and Abe, Jun and von Werdt, Diego and Wissmann, Stefanie and Magdaleno, Jose Martínez and Francisco, David and van Geest, Geert and Ficht, Xenia and Iannacone, Matteo and Bruggmann, Remy and Mueller, Christoph and Stein, Jens V.,
Science Immunology
7.72
(2022), eabf1861
| Article
3-Dimensional Imaging Reveals Immune-Driven Tumour-Associated High Endothelial Venules as a Key Correlate of Tumour Rejection Following Depletion of Regulatory T Cells
Milutinovic, Stefan and Abe, Jun and Jones, Emma and Kelch, Inken and Smart, Kathryn and Lauder, Sarah N and Somerville, Michelle and Ware, Carl and Godkin, Andrew and Stein, Jens V. and Bogle, Gib and Gallimore, Awen,
Cancer Research Communications
2.12
(2022), 1641–1656
| Article
Multitier Mechanics Control Stromal Adaptations in the Swelling Lymph Node
Assen, Frank P. and Abe, Jun and Hons, Miroslav and Hauschild, Robert and Shamipour, Shayan and Kaufmann, Walter A. and Costanzo, Tommaso and Krens, Gabriel and Brown, Markus and Ludewig, Burkhard and Hippenmeyer, Simon and Heisenberg, Carl-Philipp and Weninger, Wolfgang and Hannezo, Edouard and Luther, Sanjiv A. and Stein, Jens V. and Sixt, Michael,
Nature Immunology
23.8
(2022), 1246–1255
| Article
Ibrutinib Does Not Impact CCR7-Mediated Homeostatic Migration in T-Cells from Chronic Lymphocytic Leukemia Patients
Mateu-Albero, Tamara and Marcos-Jimenez, Ana and Wissmann, Stefanie and Loscertales, Javier and Terrón, Fernando and Stein, Jens V. and Muñoz-Calleja, Cecilia and Cuesta-Mateos, Carlos,
Cancers
14.11
(2022), 2729
| Article
CD169+ Macrophages in Lymph Node and Spleen Critically Depend on Dual RANK and LTbetaR Signaling
Camara, Abdouramane and Lavanant, Alice C. and Abe, Jun and Desforges, Henri Lee and Alexandre, Yannick O. and Girardi, Erika and Igamberdieva, Zinaida and Asano, Kenichi and Tanaka, Masato and Hehlgans, Thomas and Pfeffer, Klaus and Pfeffer, Sébastien and Mueller, Scott N. and Stein, Jens V. and Mueller, Christopher G.,
Proceedings of the National Academy of Sciences
119.3
(2022), e2108540119
| Article
Simulating CXCR5 Dynamics in Complex Tissue Microenvironments
Cosgrove, Jason and Alden, Kieran and Stein, Jens V. and Coles, Mark C. and Timmis, Jon,
Frontiers in Immunology
12
(2021), 703088
| Article
Organ-Specific Surveillance and Long-Term Residency Strategies Adapted by Tissue-Resident Memory CD8+ T Cells
Stein, Jens V. and Ruef, Nora and Wissmann, Stefanie,
Frontiers in Immunology
12
(2021), 626019
| Article
The Tec Kinase Itk Integrates Naïve T Cell Migration and In Vivo Homeostasis
Thelen, Flavian and Wissmann, Stefanie and Ruef, Nora and Stein, Jens V.,
Frontiers in Immunology
12
(2021), 716405
| Article
Immune Synapse Instructs Epigenomic and Transcriptomic Functional Reprogramming in Dendritic Cells
Alcaraz-Serna, Ana and Bustos-Morán, Eugenio and Fernández-Delgado, Irene and Calzada-Fraile, Diego and Torralba, Daniel and Marina-Zárate, Ester and Lorenzo-Vivas, Erika and Vázquez, Enrique and de Alburquerque, Juliana Barreto and Ruef, Nora and Gómez, Manuel José and Sánchez-Cabo, Fátima and Dopazo, Ana and Stein, Jens V. and Ramiro, Almudena and Sánchez-Madrid, Francisco,
Science Advances
7.6
(2021), eabb9965
| Article
Dopamine, Sleep, and Neuronal Excitability Modulate Amyloid-$\beta$–Mediated Forgetting in Drosophila
Kaldun, Jenifer C. and Lone, Shahnaz R. and Camps, Ana M. Humbert and Fritsch, Cornelia and Widmer, Yves F. and Stein, Jens V. and Tomchik, Seth M. and Sprecher, Simon G.,
PLoS Biology
19.10
(2021), e3001412
| Article
Dendritic Cell Actin Dynamics Control Contact Duration and Priming Efficiency at the Immunological Synapse
Leithner, Alexander and Altenburger, Lukas M. and Hauschild, Robert and Assen, Frank P. and Rottner, Klemens and Stradal, Theresia E.B. and Diz-Muñoz, Alba and Stein, Jens V. and Sixt, Michael,
Journal of Cell Biology
220.4
(2021), e202006081
| Article
The Dual Role of High Endothelial Venules in Cancer Progression versus Immunity
Milutinovic, Stefan and Abe, Jun and Godkin, Andrew and Stein, Jens V. and Gallimore, Awen,
Trends in Cancer
7.3
(2021), 214–225
| Article
Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis
Jahromi, Neda Haghayegh and Marchetti, Luca and Moalli, Federica and Duc, Donovan and Basso, Camilla and Tardent, Heidi and Kaba, Elisa and Deutsch, Urban and Pot, Caroline and Sallusto, Federica and Stein, Jens V. and Engelhardt, Britta,
Frontiers in Immunology
10
(2020), 3056
| Article
3D Imaging of Undissected Optically Cleared Anopheles Stephensi Mosquitoes and Midguts Infected with Plasmodium Parasites
Niz, Mariana De and Kehrer, Jessica and Brancucci, Nicolas M. B. and Moalli, Federica and Reynaud, Emmanuel G. and Stein, Jens V. and Frischknecht, Friedrich,
PLoS ONE
15.9
(2020), e0238134
| Article
Salivary Gland Macrophages and Tissue-Resident CD8+ T Cells Cooperate for Homeostatic Organ Surveillance
Stolp, Bettina and Thelen, Flavian and Ficht, Xenia and Altenburger, Lukas M. and Ruef, Nora and Inavalli, V. V. G. Krishna and Germann, Philipp and Page, Nicolas and Moalli, Federica and Raimondi, Andrea and Keyser, Kirsten A. and Jafari, S. Morteza Seyed and Barone, Francesca and Dettmer, Matthias S. and Merkler, Doron and Iannacone, Matteo and Sharpe, James and Schlapbach, Christoph and Fackler, Oliver T. and Nägerl, U. Valentin and Stein, Jens V.,
Science Immunology
5.46
(2020), eaaz4371
| Article
B Cell Zone Reticular Cell Microenvironments Shape CXCL13 Gradient Formation
Cosgrove, Jason and Novkovic, Mario and Albrecht, Stefan and Pikor, Natalia B. and Zhou, Zhaoukun and Onder, Lucas and Mörbe, Urs and Cupovic, Jovana and Miller, Helen and Alden, Kieran and Thuery, Anne and O'Toole, Peter and Pinter, Rita and Jarrett, Simon and Taylor, Emily and Venetz, Daniel and Heller, Manfred and Uguccioni, Mariagrazia and Legler, Daniel F. and Lacey, Charles J. and Coatesworth, Andrew and Polak, Wojciech G. and Cupedo, Tom and Manoury, Bénedicte and Thelen, Marcus and Stein, Jens V. and Wolf, Marlene and Leake, Mark C. and Timmis, Jon and Ludewig, Burkhard and Coles, Mark C.,
Nature Communications
11.1
(2020), 3677
| Article
Dynamic Spherical Harmonics Approach for Shape Classification of Migrating Cells
Medyukhina, Anna and Blickensdorf, Marco and Cseresnyés, Zoltán and Ruef, Nora and Stein, Jens V. and Figge, Marc Thilo,
Scientific Reports
10.1
(2020), 6072
| Article
Initial Viral Inoculum Determines Kinapse-and Synapse-Like T Cell Motility in Reactive Lymph Nodes
Sivapatham, Sujana and Ficht, Xenia and de Albuquerque, Juliana Barreto and Page, Nicolas and Merkler, Doron and Stein, Jens V.,
Frontiers in Immunology
10
(2019), 2086
| Article
Influenza Vaccination Induces NK-Cell-Mediated Type-II IFN Response That Regulates Humoral Immunity in an IL-6-Dependent Manner
Farsakoglu, Yagmur and Palomino-Segura, Miguel and Latino, Irene and Zanaga, Silvia and Chatziandreou, Nikolaos and Pizzagalli, Diego Ulisse and Rinaldi, Andrea and Bolis, Marco and Sallusto, Federica and Stein, Jens V. and Gonzalez, Santiago F.,
Cell Reports
26.9
(2019), 2307–2315.e5
| Article
A Network of Trans-Cortical Capillaries as Mainstay for Blood Circulation in Long Bones
Grüneboom, Anika and Hawwari, Ibrahim and Weidner, Daniela and Culemann, Stephan and Müller, Sylvia and Henneberg, Sophie and Brenzel, Alexandra and Merz, Simon and Bornemann, Lea and Zec, Kristina and Wuelling, Manuela and Kling, Lasse and Hasenberg, Mike and Voortmann, Sylvia and Lang, Stefanie and Baum, Wolfgang and Ohs, Alexandra and Kraff, Oliver and Quick, Harald H. and Jäger, Marcus and Landgraeber, Stefan and Dudda, Marcel and Danuser, Renzo and Stein, Jens V. and Rohde, Manfred and Gelse, Kolja and Garbe, Annette I. and Adamczyk, Alexandra and Westendorf, Astrid M. and Hoffmann, Daniel and Christiansen, Silke and Engel, Daniel Robert and Vortkamp, Andrea and Krönke, Gerhard and Herrmann, Martin and Kamradt, Thomas and Schett, Georg and Hasenberg, Anja and Gunzer, Matthias,
Nature Metabolism
1.2
(2019), 236–250
| Article
Vaccination with Nanoparticles Combined with Micro-Adjuvants Protects against Cancer
Mohsen, Mona O. and Heath, Matthew D. and Cabral-Miranda, Gustavo and Lipp, Cyrill and Zeltins, Andris and Sande, Marcos and Stein, Jens V. and Riether, Carsten and Roesti, Elisa and Zha, Lisha and Engeroff, Paul and El-Turabi, Aadil and Kundig, Thomas M. and Vogel, Monique and Skinner, Murray A. and Speiser, Daniel E. and Knuth, Alexander and Kramer, Matthias F. and Bachmann, Martin F.,
Journal for ImmunoTherapy of Cancer
7.1
(2019), 114
| Article
Toolbox for In Vivo Imaging of Host–Parasite Interactions at Multiple Scales
Niz, Mariana De and Spadin, Florentin and Marti, Matthias and Stein, Jens V. and Frenz, Martin and Frischknecht, Friedrich,
Trends in Parasitology
35.3
(2019), 193–212
| Article
T Cells Loaded with Magnetic Nanoparticles Are Retained in Peripheral Lymph Nodes by the Application of a Magnetic Field
Sanz-Ortega, Laura and Rojas, José M. and Marcos, Ana and Portilla, Yadileiny and Stein, Jens V. and Barber, Domingo F.,
Journal of Nanobiotechnology
17.1
(2019), 14
| Article
Regulation of Global CD8+ T-cell Positioning by the Actomyosin Cytoskeleton
Stein, Jens V. and Ruef, Nora,
Immunological Reviews
289.1
(2019), 232–249
| Article
In Vivo Function of the Lipid Raft Protein Flotillin-1 during CD8+ T Cell–Mediated Host Surveillance
Ficht, Xenia and Ruef, Nora and Stolp, Bettina and Samson, Guerric P. B. and Moalli, Federica and Page, Nicolas and Merkler, Doron and Nichols, Ben J. and Diz-Muñoz, Alba and Legler, Daniel F. and Niggli, Verena and Stein, Jens V.,
The Journal of Immunology
203.9
(2019), 2377–2387
| Article
TNF$\alpha$ Blockade Mediates Bone Protection in Antigen-Induced Arthritis by Reducing Osteoclast Precursor Supply
Uster, Stephanie and Coelho, Fernanda Matos and Aeberli, Daniel and Stein, Jens V. and Hofstetter, Wilhelm and Engelhardt, Britta and Seitz, Michael,
Bone
107
(2018), 56–65
| Article
Oral Versus Intragastric Inoculation: Similar Pathways of Trypanosoma Cruzi Experimental Infection? From Target Tissues, Parasite Evasion, and Immune Response
de Albuquerque, Juliana Barreto and dos Santos, Danielle Silva and Stein, Jens V. and de Meis, Juliana,
Frontiers in Immunology
9
(2018), 1734
| Article
Fam65b Phosphorylation Relieves Tonic RhoA Inhibition During T Cell Migration
Megrelis, Laura and Ghoul, Elyas El and Moalli, Federica and Versapuech, Margaux and Cassim, Shamir and Ruef, Nora and Stein, Jens V. and Mangeney, Marianne and Delon, Jérôme,
Frontiers in Immunology
9
(2018), 2001
| Article
The Rho Regulator Myosin IXb Enables Nonlymphoid Tissue Seeding of Protective CD8+ T Cells
Moalli, Federica and Ficht, Xenia and Germann, Philipp and Vladymyrov, Mykhailo and Stolp, Bettina and de Vries, Ingrid and Lyck, Ruth and Balmer, Jasmin and Fiocchi, Amleto and Kreutzfeldt, Mario and Merkler, Doron and Iannacone, Matteo and Ariga, Akitaka and Stoffel, Michael H. and Sharpe, James and Bähler, Martin and Sixt, Michael and Diz-Muñoz, Alba and Stein, Jens V.,
Journal of Experimental Medicine
215.7
(2018), 1869–1890
| Article
Chemokines and Integrins Independently Tune Actin Flow and Substrate Friction during Intranodal Migration of T Cells
Hons, Miroslav and Kopf, Aglaja and Hauschild, Robert and Leithner, Alexander and Gaertner, Florian and Abe, Jun and Renkawitz, Jörg and Stein, Jens V. and Sixt, Michael,
Nature Immunology
19.6
(2018), 606–616
| Article
HIV-1 Nef Disrupts CD4+ T Lymphocyte Polarity, Extravasation, and Homing to Lymph Nodes via Its Nef-Associated Kinase Complex Interface
Lamas-Murua, Miguel and Stolp, Bettina and Kaw, Sheetal and Thoma, Judith and Tsopoulidis, Nikolaos and Trautz, Birthe and Ambiel, Ina and Reif, Tatjana and Arora, Sakshi and Imle, Andrea and Tibroni, Nadine and Wu, Jingxia and Cui, Guoliang and Stein, Jens V. and Tanaka, Motomu and Lyck, Ruth and Fackler, Oliver T.,
The Journal of Immunology
201.9
(2018), 2731–2743
| Article
Leukocyte Tracking Database, a Collection of Immune Cell Tracks from Intravital 2-Photon Microscopy Videos
Pizzagalli, Diego Ulisse and Farsakoglu, Yagmur and Palomino-Segura, Miguel and Palladino, Elisa and Sintes, Jordi and Marangoni, Francesco and Mempel, Thorsten R. and Koh, Wan Hon and Murooka, Thomas T. and Thelen, Flavian and Stein, Jens V. and Pozzi, Giuseppe and Thelen, Marcus and Krause, Rolf and Gonzalez, Santiago Fernandez,
Scientific Data
5.1
(2018), 180129
| Article
Preparation of Murine Submandibular Salivary Gland for Upright Intravital Microscopy
Ficht, Xenia and Thelen, Flavian and Stolp, Bettina and Stein, Jens V,
Journal of Visualized Experiments
215.135
(2018), 1869–1890
| Article
VLA-4 Mediated Adhesion of Melanoma Cells on the Blood–Brain Barrier Is the Critical Cue for Melanoma Cell Intercalation and Barrier Disruption
García-Martín, Ana B and Zwicky, Pascale and Gruber, Thomas and Matti, Christoph and Moalli, Federica and Stein, Jens V and Francisco, David and Enzmann, Gaby and Levesque, Mitchell P and Hewer, Ekkehard and Lyck, Ruth,
Journal of Cerebral Blood Flow & Metabolism
39.10
(2018), 1995–2010
| Article
A Minimum Number of Autoimmune T Cells to Induce Autoimmunity?
Bosch, Angela J.T. and Bolinger, Beatrice and Keck, Simone and Stepanek, Ondrej and Ozga, Aleksandra J. and Galati-Fournier, Virginie and Stein, Jens V. and Palmer, Ed,
Cellular Immunology
316
(2017), 21–31
| Article
Delivering Adjuvants and Antigens in Separate Nanoparticles Eliminates the Need of Physical Linkage for Effective Vaccination
Mohsen, Mona O. and Gomes, Ariane C. and Cabral-Miranda, Gustavo and Krueger, Caroline C. and Leoratti, Fabiana MS and Stein, Jens V. and Bachmann, Martin F.,
Journal of Controlled Release
251.C
(2017), 92–100
| Article
Antigen Availability and DOCK2-Driven Motility Govern CD4+ T Cell Interactions with Dendritic Cells In Vivo
Ackerknecht, Markus and Gollmer, Kathrin and Germann, Philipp and Ficht, Xenia and Abe, Jun and Fukui, Yoshinori and Swoger, Jim and Ripoll, Jorge and Sharpe, James and Stein, Jens V.,
The Journal of Immunology
199.2
(2017), 520–530
| Article
Dynamic Intravital Imaging of Cell-Cell Interactions in the Lymph Node
Stein, Jens V. and Gonzalez, Santiago F.,
Journal of Allergy and Clinical Immunology
139.1
(2017), 12–20
| Article
Efficient T-cell Priming and Activation Requires Signaling through Prostaglandin E2 (EP) Receptors
Sreeramkumar, Vinatha and Hons, Miroslav and Punzón, Carmen and Stein, Jens V and Sancho, David and Fresno, Manuel and Cuesta, Natalia,
Immunology and Cell Biology
94.1
(2016), 39–51
| Article
Light Sheet Fluorescence Microscopy for in Situ Cell Interaction Analysis in Mouse Lymph Nodes
Abe, Jun and Ozga, Aleksandra J. and Swoger, Jim and Sharpe, James and Ripoll, Jorge and Stein, Jens V.,
Journal of Immunological Methods
431
(2016), 1–10
| Article
pMHC Affinity Controls Duration of CD8+ T Cell–DC Interactions and Imprints Timing of Effector Differentiation versus Expansion
Ozga, Aleksandra J. and Moalli, Federica and Abe, Jun and Swoger, Jim and Sharpe, James and Zehn, Dietmar and Kreutzfeldt, Mario and Merkler, Doron and Ripoll, Jorge and Stein, Jens V.,
Journal of Experimental Medicine
213.12
(2016), 2811–2829
| Article
Real-Time Tissue Offset Correction System for Intravital Multiphoton Microscopy
Vladymyrov, Mykhailo and Abe, Jun and Moalli, Federica and Stein, Jens V. and Ariga, Akitaka,
Journal of Immunological Methods
438
(2016), 35–41
| Article
WNK1 Kinase Balances T Cell Adhesion versus Migration in Vivo
Köchl, Robert and Thelen, Flavian and Vanes, Lesley and Brazão, Tiago F and Fountain, Kathryn and Xie, Jian and Huang, Chou-Long and Lyck, Ruth and Stein, Jens V and Tybulewicz, Victor L J,
Nature Immunology
17.9
(2016), 1075–1083
| Article
Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
Novkovic, Mario and Onder, Lucas and Cupovic, Jovana and Abe, Jun and Bomze, David and Cremasco, Viviana and Scandella, Elke and Stein, Jens V. and Bocharov, Gennady and Turley, Shannon J. and Ludewig, Burkhard,
PLoS Biology
14.7
(2016), e1002515
| Article
The Outer Mucus Layer Hosts a Distinct Intestinal Microbial Niche
Li, Hai and Limenitakis, Julien P. and Fuhrer, Tobias and Geuking, Markus B. and Lawson, Melissa A. and Wyss, Madeleine and Brugiroux, Sandrine and Keller, Irene and Macpherson, Jamie A. and Rupp, Sandra and Stolp, Bettina and Stein, Jens V. and Stecher, Bärbel and Sauer, Uwe and McCoy, Kathy D. and Macpherson, Andrew J.,
Nature Communications
6.1
(2015), 8292
| Article
T Cell Motility as Modulator of Interactions with Dendritic Cells
Stein, Jens V.,
Frontiers in Immunology
6
(2015), 559
| Article
The Kinases NDR1/2 Act Downstream of the Hippo Homolog MST1 to Mediate Both Egress of Thymocytes from the Thymus and Lymphocyte Motility
Tang, Fengyuan and Gill, Jason and Ficht, Xenia and Barthlott, Thomas and Cornils, Hauke and Schmitz-Rohmer, Debora and Hynx, Debby and Zhou, Dawang and Zhang, Lei and Xue, Gongda and Grzmil, Michal and Yang, Zhongzhou and Hergovich, Alexander and Hollaender, Georg A. and Stein, Jens V. and Hemmings, Brian A. and Matthias, Patrick,
Science Signaling
8.397
(2015), ra100
| Article
In Vivo TCR Signaling in CD4+ T Cells Imprints a Cell-Intrinsic, Transient Low-Motility Pattern Independent of Chemokine Receptor Expression Levels, or Microtubular Network, Integrin, and Protein Kinase C Activity
Ackerknecht, Markus and Hauser, Mark A. and Legler, Daniel F. and Stein, Jens V.,
Frontiers in Immunology
6.6
(2015), 297
| Article
Intravital and Whole-Organ Imaging Reveals Capture of Melanoma-Derived Antigen by Lymph Node Subcapsular Macrophages Leading to Widespread Deposition on Follicular Dendritic Cells
Moalli, Federica and Proulx, Steven T. and Schwendener, Reto and Detmar, Michael and Schlapbach, Christoph and Stein, Jens V.,
Frontiers in Immunology
6.8
(2015), 114
| Article
Lymph Node Stromal Cells Negatively Regulate Antigen-Specific CD4+ T Cell Responses
Abe, Jun and Shichino, Shigeyuki and Ueha, Satoshi and Hashimoto, Shin-ichi and Tomura, Michio and Inagaki, Yutaka and Stein, Jens V. and Matsushima, Kouji,
The Journal of Immunology
193.4
(2014), 1636–1644
| Article
OPTiSPIM: Integrating Optical Projection Tomography in Light Sheet Microscopy Extends Specimen Characterization to Nonfluorescent Contrasts
Mayer, Jürgen and Robert-Moreno, Alexandre and Danuser, Renzo and Stein, Jens V. and Sharpe, James and Swoger, Jim,
Optics Letters
39.4
(2014), 1053
| Article
Sensory Innervation of the Dorsal Longitudinal Ligament and the Meninges in the Lumbar Spine of the Dog
Waber-Wenger, Barbara and Forterre, Franck and Kuehni-Boghenbor, Kathrin and Danuser, Renzo and Stein, Jens Volker and Stoffel, Michael Hubert,
Histochemistry and Cell Biology
142.4
(2014), 433–447
| Article
The Chemokine Receptors ACKR2 and CCR2 Reciprocally Regulate Lymphatic Vessel Density
Lee, Kit M and Danuser, Renzo and Stein, Jens V and Graham, Delyth and Nibbs, Robert JB and Graham, Gerard J,
The EMBO Journal
33.21
(2014), 2564–2580
| Article
Thromboxane A2 Acts as Tonic Immunoregulator by Preferential Disruption of Low-Avidity CD4+ T Cell–Dendritic Cell Interactions
Moalli, Federica and Cupovic, Jovana and Thelen, Flavian and Halbherr, Pascal and Fukui, Yoshinori and Narumiya, Shuh and Ludewig, Burkhard and Stein, Jens V.,
Journal of Experimental Medicine
211.13
(2014), 2507–2517
| Article
Comprehensive Assessment of Quantum Dots for Multispectral Twophoton Imaging of Dynamic Leukocyte Migration in Lymph Nodes
Natale, Daniela and Soriano, Silvia F and Coelho, Fernanda M and Hons, Miroslav and Stein, Jens V,
IntraVital
2.2
(2013), e25745
| Article
Naive B-cell Trafficking Is Shaped by Local Chemokine Availability and LFA-1–Independent Stromal Interactions
Coelho, Fernanda M. and Natale, Daniela and Soriano, Silvia F. and Hons, Miroslav and Swoger, Jim and Mayer, Jürgen and Danuser, Renzo and Scandella, Elke and Pieczyk, Markus and Zerwes, Hans-Günter and Junt, Tobias and Sailer, Andreas W. and Ludewig, Burkhard and Sharpe, James and Figge, Marc Thilo and Stein, Jens V.,
Blood
121.20
(2013), 4101–4109
| Article
Automated Recovery of the Center of Rotation in Optical Projection Tomography in the Presence of Scattering
Dong, Di and Zhu, Shouping and Qin, Chenghu and Kumar, Varsha and Stein, Jens V. and Oehler, Stephan and Savakis, Charalambos and Tian, Jie and Ripoll, Jorge,
IEEE Journal of Biomedical and Health Informatics
17.1
(2013), 198–204
| Article
Janus Kinases 1 and 2 Regulate Chemokine-mediated Integrin Activation and Naïve T-cell Homing
Pérez-Rivero, Gema and Cascio, Graciela and Soriano, Silvia Fernández and Sanz, Álvaro Gil and Guinoa, Julia Sáez and Rodríguez-Frade, José Miguel and Gomariz, Rosa P. and Holgado, Borja L. and Cabañas, Carlos and Carrasco, Yolanda R. and Stein, Jens V. and Mellado, Mario,
European Journal of Immunology
43.7
(2013), 1745–1757
| Article
Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity
Chai, Qian and Onder, Lucas and Scandella, Elke and Gil-Cruz, Cristina and Perez-Shibayama, Christian and Cupovic, Jovana and Danuser, Renzo and Sparwasser, Tim and Luther, Sanjiv A. and Thiel, Volker and Rülicke, Thomas and Stein, Jens V. and Hehlgans, Thomas and Ludewig, Burkhard,
Immunity
38.5
(2013), 1013–1024
| Article
Endothelial Cell–Specific Lymphotoxin-$\beta$ Receptor Signaling Is Critical for Lymph Node and High Endothelial Venule Formation
Onder, Lucas and Danuser, Renzo and Scandella, Elke and Firner, Sonja and Chai, Qian and Hehlgans, Thomas and Stein, Jens V. and Ludewig, Burkhard,
Journal of Experimental Medicine
210.3
(2013), 465–473
| Article
Optical Projection Tomography Reveals Dynamics of HEV Growth after Immunization with Protein plus CFA and Features Shared with HEVs in Acute Autoinflammatory Lymphadenopathy
Kumar, Varsha and Chyou, Susan and Stein, Jens V. and Lu, Theresa T.,
Frontiers in Immunology
3
(2012), 282
| Article
Paracrine Effects of Mesenchymal Stem Cells Enhance Vascular Regeneration in Ischemic Murine Skin
Schlosser, Stefan and Dennler, Cyrill and Schweizer, Riccardo and Eberli, Daniel and Stein, Jens V. and Enzmann, Volker and Giovanoli, Pietro and Erni, Dominique and Plock, Jan A.,
Microvascular Research
83.3
(2012), 267–275
| Article
A Global "imaging" View on Systems Approaches in Immunology
Ludewig, Burkhard and Stein, Jens V. and Sharpe, James and Cervantes-Barragan, Luisa and Thiel, Volker and Bocharov, Gennady,
European Journal of Immunology
42.12
(2012), 3116–3125
| Article
Quantitative Measurements in 3-Dimensional Datasets of Mouse Lymph Nodes Resolve Organ-Wide Functional Dependencies
Mayer, Jürgen and Swoger, Jim and Ozga, Aleksandra J. and Stein, Jens V. and Sharpe, James,
Computational and Mathematical Methods in Medicine
2012.11
(2012), 128431
| Article
DOCK8 Is a Cdc42 Activator Critical for Interstitial Dendritic Cell Migration during Immune Responses
Harada, Yosuke and Tanaka, Yoshihiko and Terasawa, Masao and Pieczyk, Markus and Habiro, Katsuyoshi and Katakai, Tomoya and Hanawa-Suetsugu, Kyoko and Kukimoto-Niino, Mutsuko and Nishizaki, Tomoko and Shirouzu, Mikako and Duan, Xuefeng and Uruno, Takehito and Nishikimi, Akihiko and Sanematsu, Fumiyuki and Yokoyama, Shigeyuki and Stein, Jens V. and Kinashi, Tatsuo and Fukui, Yoshinori,
Blood
119.19
(2012), 4451–4461
| Article
HIV-1 Nef Interferes with T-lymphocyte Circulation through Confined Environments in Vivo
Stolp, Bettina and Imle, Andrea and Coelho, Fernanda Matos and Hons, Miroslav and Gorina, Roser and Lyck, Ruth and Stein, Jens V. and Fackler, Oliver T.,
Proceedings of the National Academy of Sciences
109.45
(2012), 18541–18546
| Article
CD69 Modulates Sphingosine-1-Phosphate-Induced Migration of Skin Dendritic Cells
Lamana, Amalia and Martin, Pilar and de la Fuente, Hortensia and Martinez-Muñoz, Laura and Cruz-Adalia, Aranzazu and Ramirez-Huesca, Marta and Escribano, Cristina and Gollmer, Kathrin and Mellado, Mario and Stein, Jens V. and Rodriguez-Fernandez, Jose Luis and Sanchez-Madrid, Francisco and del Hoyo, Gloria Martinez,
Journal of Investigative Dermatology
131.7
(2011), 1503–1512
| Article
In Vivo Analysis of Uropod Function during Physiological T Cell Trafficking
Soriano, Silvia F. and Hons, Miroslav and Schumann, Kathrin and Kumar, Varsha and Dennier, Timo J. and Lyck, Ruth and Sixt, Michael and Stein, Jens V.,
The Journal of Immunology
187.5
(2011), 2356–2364
| Article
Global Lymphoid Tissue Remodeling during a Viral Infection Is Orchestrated by a B Cell–Lymphotoxin-Dependent Pathway
Kumar, Varsha and Scandella, Elke and Danuser, Renzo and Onder, Lucas and Nitschké, Maximilian and Fukui, Yoshinori and Halin, Cornelia and Ludewig, Burkhard and Stein, Jens V.,
Blood
115.23
(2010), 4725–4733
| Article
Comprehensive Analysis of Lymph Node Stroma-Expressed Ig Superfamily Members Reveals Redundant and Nonredundant Roles for ICAM-1, ICAM-2, and VCAM-1 in Lymphocyte Homing
Boscacci, Rémy T. and Pfeiffer, Friederike and Gollmer, Kathrin and Sevilla, Ana Isabel Checa and Martin, Ana Maria and Soriano, Silvia Fernandez and Natale, Daniela and Henrickson, Sarah and von Andrian, Ulrich H. and Fukui, Yoshinori and Mellado, Mario and Deutsch, Urban and Engelhardt, Britta and Stein, Jens V.,
Blood
116.6
(2010), 915–925
| Article
Critical Roles for Rac GTPases in T-cell Migration to and within Lymph Nodes
Faroudi, Mustapha and Hons, Miroslav and Zachacz, Agnieszka and Dumont, Celine and Lyck, Ruth and Stein, Jens V. and Tybulewicz, Victor L.J.,
Blood
116.25
(2010), 5536–5547
| Article
Close Encounters of the 3D Kind
Stein, Jens V.,
Blood
113.23
(2009), 5698–5699
| Article
How to Be Naive
Stein, Jens V.,
Immunity
31.1
(2009), 9–11
| Article
CCL21 Mediates CD4+ T-cell Costimulation via a DOCK2/Rac-dependent Pathway
Gollmer, Kathrin and Asperti-Boursin, François and Tanaka, Yoshihiko and Okkenhaug, Klaus and Vanhaesebroeck, Bart and Peterson, Jeffrey R. and Fukui, Yoshinori and Donnadieu, Emmanuel and Stein, Jens V.,
Blood
114.3
(2009), 580–588
| Article
Statins Induce Regulatory T Cell Recruitment via a CCL1 Dependent Pathway
Mira, Emilia and León, Beatriz and Barber, Domingo F. and Jiménez-Baranda, Sonia and Goya, Iñigo and Almonacid, Luis and Márquez, Gabriel and Zaballos, Angel and Martínez-A., Carlos and Stein, Jens V. and Ardavín, Carlos and Mañes, Santos,
The Journal of Immunology
181.5
(2008), 3524–3534
| Article
Distinct Molecular Composition of Blood and Lymphatic Vascular Endothelial Cell Junctions Establishes Specific Functional Barriers within the Peripheral Lymph Node
Pfeiffer, Friederike and Kumar, Varsha and Butz, Stefan and Vestweber, Dietmar and Imhof, Beat A. and Stein, Jens V. and Engelhardt, Britta,
European Journal of Immunology
38.8
(2008), 2142–2155
| Article
How Chemokines Invite Leukocytes to Dance
Thelen, Marcus and Stein, Jens V,
Nature Immunology
9.9
(2008), 953–959
| Article
L-Selectin-Negative CCR7- Effector and Memory CD8+ T Cells Enter Reactive Lymph Nodes and Kill Dendritic Cells
Guarda, Greta and Hons, Miroslav and Soriano, Silvia F and Huang, Alex Y and Polley, Rosalind and Martín-Fontecha, Alfonso and Stein, Jens V and Germain, Ronald N and Lanzavecchia, Antonio and Sallusto, Federica,
Nature Immunology
8.7
(2007), 743–752
| Article
A Central Role for DOCK2 during Interstitial Lymphocyte Motility and Sphingosine-1-Phosphate–Mediated Egress
Nombela-Arrieta, César and Mempel, Thorsten R. and Soriano, Silvia F. and Mazo, Irina and Wymann, Matthias P. and Hirsch, Emilio and Martínez-A., Carlos and Fukui, Yoshinori and von Andrian, Ulrich H. and Stein, Jens V.,
The Journal of Experimental Medicine
204.3
(2007), 497–510
| Article
DOCK2 Is Required for Chemokine-Promoted Human T Lymphocyte Adhesion Under Shear Stress Mediated by the Integrin $\alpha$4$\beta$1
García-Bernal, David and Sotillo-Mallo, Elena and Nombela-Arrieta, César and Samaniego, Rafael and Fukui, Yoshinori and Stein, Jens V. and Teixidó, Joaquin,
The Journal of Immunology
177.8
(2006), 5215–5225
| Article
Opioids Trigger $\alpha$5$\beta$1 Integrin-Mediated Monocyte Adhesion
Pello, Oscar M. and Duthey, Béatrice and García-Bernal, David and Rodríguez-Frade, José Miguel and Stein, Jens V. and Teixido, Joaquín and Martínez-A., Carlos and Mellado, Mario,
The Journal of Immunology
176.3
(2006), 1675–1685
| Article
Vav1 and Rac Control Chemokine-promoted T Lymphocyte Adhesion Mediated by the Integrin $\alpha$4$\beta$1
García-Bernal, David and Wright, Natalia and Sotillo-Mallo, Elena and Nombela-Arrieta, César and Stein, Jens V. and Bustelo, Xosé R. and Teixidó, Joaquin,
Molecular Biology of the Cell
16.7
(2005), 3223–3235
| Article
Chemokine Control of Lymphocyte Trafficking: A General Overview
Stein, Jens V. and Nombela-Arrieta, César,
Immunology
116.1
(2005), 1–12
| Article
Differential Requirements for DOCK2 and Phosphoinositide-3-Kinase $\gamma$ during T and B Lymphocyte Homing
Nombela-Arrieta, César and Lacalle, Rosa Ana and Montoya, María C. and Kunisaki, Yuya and Megías, Diego and Marqués, Miriam and Carrera, Ana C. and Mañes, Santos and Fukui, Yoshinori and Martínez-A, Carlos and Stein, Jens V.,
Immunity
21.3
(2004), 429–441
| Article
CXCL12 Mediates CCR7-independent Homing of Central Memory Cells, But Not Naive T Cells, in Peripheral Lymph Nodes
Scimone, M. Lucila and Felbinger, Thomas W. and Mazo, Irina B. and Stein, Jens V. and von Andrian, Ulrich H. and Weninger, Wolfgang,
The Journal of Experimental Medicine
199.8
(2004), 1113–1120
| Article
DOCK2 Regulates Rac Activation and Cytoskeletal Reorganization through Interaction with ELMO1
Sanui, Terukazu and Inayoshi, Ayumi and Noda, Mayuko and Iwata, Eiko and Stein, Jens V. and Sasazuki, Takehiko and Fukui, Yoshinori,
Blood
102.8
(2003), 2948–2950
| Article
CCR7-mediated Physiological Lymphocyte Homing Involves Activation of a Tyrosine Kinase Pathway
Stein, Jens V. and Soriano, Silvia F. and M'rini, Christine and Nombela-Arrieta, César and de Buitrago, Gonzalo González and Rodríguez-Frade, José Miguel and Mellado, Mario and Girard, Jean-Philippe and Martínez-A., Carlos,
Blood
101.1
(2003), 38–44
| Article
APRIL Modulates B and T Cell Immunity
Stein, Jens V. and López-Fraga, Marta and Elustondo, Fernando A. and Carvalho-Pinto, Carla E. and Rodríguez, Dolores and Gómez-Caro, Ruth and de Jong, Joan and Martínez-A, Carlos and Medema, Jan Paul and Hahne, Michael,
Journal of Clinical Investigation
109.12
(2002), 1587–1598
| Article
The Cc Chemokine Thymus-Derived Chemotactic Agent 4 (Tca-4, Secondary Lymphoid Tissue Chemokine, 6ckine, Exodus-2) Triggers Lymphocyte Function–Associated Antigen 1–Mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules
Stein, Jens V. and Rot, Antal and Luo, Yi and Narasimhaswamy, Manjunath and Nakano, Hideki and Gunn, Michael D. and Matsuzawa, Akio and Quackenbush, Elizabeth J. and Dorf, Martin E. and von Andrian, Ulrich H.,
The Journal of Experimental Medicine
191.1
(2000), 61–76
| Article
L-Selectin–Mediated Leukocyte Adhesion In Vivo: Microvillous Distribution Determines Tethering Efficiency, But Not Rolling Velocity
Stein, Jens V. and Cheng, Guiying and Stockton, Britt M. and Fors, Brian P. and Butcher, Eugene C. and von Andrian, Ulrich H.,
The Journal of Experimental Medicine
189.1
(1999), 37–50
| Article
