Publication "hot spot"

Recent publications at the Department where the WOS Impact Factor is >5 are referenced here:

Larderet I, Fritsch PMJ, Gendre N, Neagu-Maier GL, Fetter RD, Schneider-Mizell CM, Truman JW, Zlatic M, Cardona A & Sprecher SG (2017). Organization of the Drosophila larval visual circuit. eLife 2017;6:e28387 DOI: 10.7554/eLife.28387. This publication is the subject of a UNIFR spotlight (link).

Bacher S, Blackburn TM, Essl F, et al. (2017). Socio-economic impact classification of alien taxa (SEICAT). Methods Ecology & Evolution. 00:1–10. This publication is the subject of a UNIFR spotlight (link).

Rich MK, Nouri E, Courty PE & Reinhardt D (2017). Diet of arbuscular mycorrhizal fungi: bread and butter? Trends in Plant Science 22: 652-660 (online (coverpage)

C. Xu, A. Messina, E. Somm et al. including U. Albrecht (2017). KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism. EMBO Molecular Medicine (DOI: 10.15252/emmm.201607376).

Kressler D, Hurt E & Bassler J (2017). A puzzle of life: crafting ribosomal subunits. Trends in Biochemcal Sciences 8: 640-645 (online DOI:

Soares TA, Vanni S, Milano G & Cascella M (2017). Toward chemically resolved computer simulations of dynamics and remodeling of biological membranes. Journal of Physical Chemistry Letters 8: 3586–3594.

Gros-Balthazard M, Galimberti M, Kousathanas A, Newton C, Ivorra S, Paradis L, Vigouroux Y, Carter R, Tengberg M, Battesti V, Santoni S, Falquet L, Pintaud JC, Terral JF & Wegmann D (2017). The discovery of wild date palms in Oman reveals a complex domestication history involving centers in the Middle East and Africa. Current Biology 27: 2211-2218.e.8 (online

Péli-Gulli MP, Raucci S, Hu Z, Dengjel JDe Virgilio C (2017). Feedback inhibition of the Rag GTPase GAP complex Lst4-Lst7 safeguards TORC1 from hyperactivation by amino acid signals. Cell Reports 20: 281-288. (link)

Gretzmeier C, Eiselein S, Johnson GR, Engelke R, Nowag H, Zarei M, Küttner V, Becker AC, Rigbolt KTG, Høyer-Hansen M, Andersen JS, Münz C, Murphy RF & Dengjel J (2017). Degradation of protein translation machinery by amino acid starvation-induced macroautophagy. Autophagy 13: 1064-1075.

Ben M'barek K, Ajjaji D, Chorlay A, Vanni S, Forêt L & Thiam AR (2017). ER membrane phospholipids and surface tension control cellular lipid droplet formation. Developmental Cell 41: 591-604.

Dumit VI, Zerbes RM, Kaeser-Pebernard S, Rackiewicz M, Wall MT, Gretzmeier C, Küttner V, van der Laan M, Braun RJ & Dengjel J (2017). Respiratory status determines the effect of emodin on cell viability. Oncotarget 8: 37478-37490.

Schell C, Rogg M, Suhm M, Helmstädter M, Sellung D, Yasuda-Yamahara M, Kretz O, Küttner V, Suleiman H, Kollipara L, Zahedi RP, Sickmann A, Eimer S, Shaw AS, Kramer-Zucker A, Hirano-Kobayashi M, Abe T, Aizawa S, Grahammer F, Hartleben B, Dengjel J & Huber TP (2017). The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier. PNAS 114: E4621-E4630 (online doi: 10.1073/pnas.1617004114).

Michel AH, Hatakeyama R, Kimmig P, Arter M, Peter M, Matos J, De Virgilio C & Kornmann B (2017). Functional mapping of yeast genomes by saturated transposition. Elife 8:  e23570 (online doi: 10.7554/eLife.23570) (link)

Pfefferli C & Jazwinska A (2017). The careg element reveals a common regulation of regeneration in the zebrafish myocardium and fin. Nature Communications 8: #15151. (link). This publication is the subject of a Unifr news spotlight.

Mène-Saffrané L & Pellaud S (2017). Current strategies for vitamin E biofortification of crops. Current Opinion in Biotechnology 44: 189-197.

Montes Vidal D, von Rymon-Lipinski AL, Ravella S, Groenhagen U, Herrmann J, Zaburannyi N, Zarbin PHG, Varadarajan AR, Ahrens CH, Weisskopf L, Müller R & Schulz S (2017). Long-chain alkyl cyanides: unprecedented volatile compounds released by Pseudomonas and Micromonospora bacteria. Angewandte Chemie Int Ed 56: 1-6.

Eisenberg T, Abdellatif M, Zimmermann A, Schroeder S, Pendl T, Harger A, Stekovic S, Schipke J, CMagnes C, Schmidt A, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Carmona-Gutierrez D, Pietrocola F, Pieber TR, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S & Madeo F (2017). Dietary spermidine for lowering high blood pressure. Autophagy 13: 767-769.

Seebens H et al. and 44 other authors including Bacher S (2017). No saturation in the accumulation of alien species worldwide. Nature Communications 8: 14435 (online: DOI: 10.1038/ncomms14435).

Kuhn BM, Nodzynski T, Errafi S, Bucher R, Gupta S, Aryal B, Dobrev P, Bigler L, Geisler M, Zazímalova E, Friml J & Ringli C (2017). Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity. Scientific Reports 7: 41906 (online doi: 10.1038/srep41906).

Brügger V, Duman M, Bochud M, Münger E, Heller M, Ruff S & Jacob C (2017). Delaying histone deacetylase early response to injury accelerates conversion into repair Schwann cells and nerve regeneration. Nature Communications 8:14272 (online doi: 10.1038/ncomms14272).

Diedrich B, Rigbolt KTG, Röring M, Herr R, Kaeser-Pebernard S, Gretzmeier C, Murphy RF, Brummer T & Dengjel J (2017). Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition. EMBO Journal 36: 646–663..

Shubchynskyy V, Boniecka J, Schweighofer A, Simulis J, Kvederaviciute K, Stumpe M, Mauch F, Balazadeh S, Mueller-Roeber B, Boutrot F, Zipfel C & Meskiene I (2017). Protein phosphatase AP2C1 negatively regulates basal resistance and defense responses to Pseudomonas syringae. Journal of Experimental Botany 68: 1169-1183

Ge Y, Yan F, Zourelidou M, Wang M, Ljung K, Fastner A, Hammes UZ, di Donato M, Geisler M, Schwechheimer C & Tao Y (2017). SHADE AVOIDANCE 4 is Required for Proper Auxin Distribution in the Hypocotyl. Plant Physiology 173: 788-800.

Gamir J, Darwiche R, van’t Hof P, Choudhary V, Stumpe M, Schneiter R & Mauch F (2017). The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein. Plant Journal 89: 502-509 (online: DOI: 10.1111/tpj.13398).

Ardissone S, Redder P, Russo G, Frandi A, Fumeaux C, Patrignani A, Schlapbach R, Falquet L & Viollier PH (2016). Cell Cycle Constraints and Environmental Control of Local DNA Hypomethylation in α-Proteobacteria. PLoS Genet 12: e1006499 (online doi:10.1371/journal.pgen.1006499).

Eisenberg T et al. (59 authors including Dengjel J) (2016). Cardioprotection and lifespan extension by the natural polyamine spermidine. Nature Medecine (online doi: doi:10.1038/nm.4222).

Kousathanas A, Leuenberger C, Link V, Sell C, Burger J & Wegmann D (2016). Inferring heterozygosity from ancient and low coverage genomes. Genetics (online: DOI: 10.1534/genetics.116.189985).

Mitterer V, Gantenbein N, Birner-Grünberger R, Murat G, Bergler H, Kressler D & Pertschy B (2016). Nuclear import of dimerized ribosomal protein Rps3 in complex with its chaperone Yar1. Scientific Reports 6:36714. (doi: 10.1038/srep36714). (pdf)

van Giesen L, Neagu-Maier GL, Kwon JY & Sprecher SG (2016). A microfluidics-based method for measuring neuronal activity in Drosophila chemosensory neurons. Nature Protocols 11: 2389-2400. (link)

Fernández-Pevida A, Martín-Villanueva S, Murat G, Lacombe T, Kressler D & de la Cruz J (2016). Nucleic Acids Research 44: 7777-7791.

Glauser DA & Goodman MB (2016). Molecules empowering animals to sense and respond to temperature in changing environments. Current Opinion in Neurobiology 41: 92-98 (online DOI:10.1016/j.conb.2016.09.006).

Duteil D, Tosic M, Lausecker F, Nenseth HZ, Müller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Brüning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T & Schüle R (2016). Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue. Cell Reports 17: 1008–1021 Online:

Gupta VK, Pech U, Bhukel A, Fulterer A, Ender A, Mauermann SF,  Andlauer TFM, Antwi-Adjei E, Beusche C, Thriene K, Maglione M, Quentin C, Bushow R, Schwaerzel M, Mielke T, Madeo F, Dengjel J, Fiala A, Sigrist SJ (2016). Spermidine suppresses age-associated memory impairment by preventing adverse increase of presynaptic active zone size and release. PLoS Biol 14(9):e1002563. doi:10.1371/journal.pbio.1002563. (link)

Käser-Pébernard S, Pfefferli C, Aschinger C & Wicky C (2016). Fine-tuning of chromatin composition and Polycomb recruitment by two Mi2 homologues during C. elegans early embryonic development. Epigenetics & Chromatin 9: 39 (online DOI: 10.1186/s13072-016-0091-3).

Jadhav S, Russo S, Cottier S, Schneiter R, L. Cowart A & Greenberg ML (2016). Valproate induces the unfolded protein response by increasing ceramide levels. Journal Biological Chemistry 291: 22253-22261. (online doi: 10.1074/jbc.M116.752634) (link)

Zürcher E, Liu J, di Donato M, Geisler M & Müller B (2016). Plant development regulated by cytokinin sinks. Science 353: 1027-1030.

Erbil S, Oral O, Mitou G, Kig C, Durmaz-Timucin E, Guven-Maiorov E, Gulacti F, Gokcen Gokce G, Dengjel J, Osman Ugur Sezerman OU & Gozuacik D (2016). RACK1 Is an interaction partner of ATG5 and a novel regulator of autophagy. Journal of Biological Chemistry 291: 16753-16765. (link)

A. Bombarely, M. Moser, A. Amrad, L. Bapaume, C. S. Barry, M. Bliek, M. R. Boersma, L. Borghi, R. Bruggmann, M. Bucher, N. D'Agostino, U. Druege, N. Dudareva, M. Egea-Cortines, M. Delledonne, N. Fernandez-Pozo, P. Franken, L. Grandont, J.S. Heslop-Harrison, J. Hintzsche, M. Johns, R. Koes, X. Lv, E. Lyons, D. Malla, E. Martinoia, N. S. Mattson, P. Morel, L. A. Mueller, J. Muhlemann, E. Nouri, V. Passeri, M. Pezzotti, Q. Qi, D. Reinhardt, M. Rich, K. R. Richert-Pöggeler, T. Robbins, M. S. Schatz, M. E. Schranz, R. C. Schuurink, T. Schwarzacher, K. Spelt, H. Tang, S. Urdanus, M. Vandenbussche, K. Vijverberg, G. H. Villarino, R. M. Warner, J. Weiss, Z. Yue, J. Zethof, F. Quattrocchio, T. L. Sims and C. Kuhlemeier (2016). Insight into the evolution of the Solanaceae from the parental genomes of Petunia hybrida. Nature Plants, 2, 16074-16082.

Vazquez HM, Vionnet C, Roubaty C, Mallela SK, Schneiter R & Conzelmann A (2016). Chemogenetic E-MAP in Saccharomyces cerevisiae for identification of embrane transporters operating lipid flip flop.PLoS Genetics 12(7): e1006160.doi:10.1371/journal.pgen.1006160. (link)

Broushaki F, Thomas MG, Link V, López S, van Dorp L, Kirsanow K, Hofmanová Z, Diekmann Y, Cassidy LM, Díez-del-Molino D, Kousathanas A, Sell C, Robson HK, Martiniano R, Blöcher J, Scheu A, Kreutzer S, Bollongino R, Bobo D, Davudi H, Munoz O, Currat M, Abdi K, Biglari F, Craig OE, Bradley DG, Shennan S, Veeramah KR, Mashkour M, Wegmann D, Hellenthal G & Burger J (2016). Early neolithic genomes from the eastern Fertile Crescent. Science (online 10.1126/science.aaf7943).

Homanova Z et al. (and 38 others including Wegmann D) (2016). Early farmers from across Europe directly descended from Neolithic Aegeans. PNAS 113: 6886-6991

Hulme PE, Bacher S, Kenis M, Kühn I, Pergl J, Pyšek P, Roques A & M Vilà M (2016). Blurring alien introduction pathways risks losing the focus on invasive species policy. Conservation Letters (online

Zhu J, Bailly A, Zwiewka M, Sovero V, di Donato M, Ge P, Oehri J, Aryal B, Hao P, Linnert M, Burgardt N, Lücke C, Weiwad M, Michel M, Weiergräber OH, Pollmann S, Azzarello E, Mancuso S, Ferro N, Fukao Y, Hoffmann C, Wedlich-Söldner R, Friml J, Thomas C & Geisler M (2016). TWISTED DWARF1 mediates the action of auxin transport inhibitors on actin cytoskeleton dynamics. Plant Cell (online doi:10.1105/tpc.15.00726).

Ferrer-Admetlla A, Leuenberger C, Jensen JD & Wegmann D (2016). An approximate Markov model for the Wright-Fisher diffusion and its application to time series data. Genetics (online DOI: 10.1534/genetics.115.184598). (link)

Sallin P & Jazwinska A  (2016). Acute stress is detrimental to heart regeneration in zebrafish. Open Biology 6:160012. (link) (also see)

Bernardo-Garcia FJ, Fritsch C & Sprecher SG (2016). The transcription factor glass links eye field specification with photoreceptor differentiation in Drosophila. Development 143: 1413-1423 (link) doi: 10.1242/dev.128801).

van Giesen L, Hernandez-Nunez L, Delasoie-Baranek S, Colombo M, Renaud P, Bruggmann R, Benton R, Samuel A & Sprecher SG (2016). Multimodal stimulus coding by a gustatory sensory neuron in Drosophila larvae. Nature Communications 7: # 10687 (doi:10.1038/ncomms10687). (link).

Chavan R, Feillet C, Fonseca Costa SS, Delorme JE, Okabe T, Ripperger JA & Albrecht U (2016). Liver-derived ketone bodies are necessary for food anticipation. Nature Communications, Article number: 10580 doi: 10.1038/ncomms10580. (link).

Mitterer V, Murat G, Réty S, Blaud M, Delbos , Stanborough T, Bergler H, Leulliot N, Kressler D & Pertschy B (2016). Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation. Nature Communications, Article number: 10336 doi: 10.1038/ncomms10336 (link).

Stahl E, Bellwon P, Huber S, Schlaeppi K, Bernsdorff F, Vallat-Michel A, Mauch F, Zeier J (2016). Regulatory and functional aspects of indolic metabolism in plant systemic acquired resistance. Molecular Plant 9: 662-681 (link)

Ramdas Nair A, Singh P, Salvador Garcia D, Rodriguez-Crespo D, Egger B & Cabernard C (2016). The microcephaly-associated proteinWdr62/CG7337 is required to maintain centrosome asymmetry in Drosophila neuroblasts. Cell Reports 14: 1100-1113 (link)

Mishra AK,  Bargmann BOR, Tsachaki M, Fritch C & Sprecher SG (2016). Functional genomics identifies Regulators of the phototransduction machinery in the drosophila larval eye and adult ocelli. Developmental Biology  410: 164-177  (link

Ritpitakphong U, Falquet L, Vimoltust A, Berger A, Métraux JP & L'Haridon F (2016). The microbiome of the leaf surface of Arabidopsis protects against a fungal pathogen. New Phytologist 210: 1033-1043 (link) 

Dept Biology - Chemin du musée 10 - 1700 Fribourg - Tel +41 26 / 300 8830 - Fax +41 26 / 300 9741
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