Kilbinger Research Group has recently published a new article in the journal ACS Macro Letters , entitled "A Single Functionalization Agent for Heterotelechelic ROMP Polymers".
For more information: https://pubs.acs.org/doi/10.1021/acsmacrolett.2c00234#.YqlwTH3gXi8
Heterotelechelic polymers are an important class of materials finding applications in bioconjugation, imaging, sensing, and synthesis of organic/inorganic hybrid systems with interesting features. However, the synthesis of such polymers is challenging. Here, we report a mechanistically unique and most efficient method based on a single functionalization agent to prepare heterotelechelic polymers by a ring-opening metathesis polymerization. Different functionalization agents can be synthesized in one simple step from inexpensive commercial starting materials. The functionalization agents initially generate a functional initiator from commercial Grubbs’ first-generation ruthenium benzylidene catalyst. During this process, a functional dihydrofuran derivative is produced. After functional initiation and propagation of a suitable monomer, the dihydrofuran derivative functionally terminates the polymerization yielding a primary alcohol-terminated heterotelechelic polymer. Molecular weight control is achieved by varying the ratio between monomer and Grubbs’ first-generation catalyst. This method may emerge as a popular choice to prepare heterotelechelic polymers due to its simplicity and efficiency.