Last Name

Site / City

Key words / Topics

AEBISCHER

GENEVA

Amyotrophic lateral sclerosis

DIGGELMANN

LAUSANNE

Retroviral vectors for hematopoietic cells

FONTANA

ZUERICH

Glyoblastoma gene therapy

FREY

BERN

Steroid mediated gene delivery

HOSSLE

ZUERICH

Chronic granulomatosis

HUEGIN

GENEVA

Intratumoral GT of melanoma

KLEMENZ

ZUERICH

Angiotoxic treatment of tumors

KOLAKOFSKY

GENEVA

Sendai virus - based vectors

LUCHSINGER

BASEL

Legal and ethical aspects

MERMOD

LAUSANNE

Vectors for regulated transgene expression

MIRKOVITCH

LAUSANNE

XLA therapy

MOELLING

ZUERICH

Retroviral vectors

REITH

GENEVA

Regulatory systems in transgenic mice

ROCHAT

GENEVA

Cystic fibrosis treatment assessment

ROCHLITZ

BASEL

IL-2 Immunotherapy of metastatic cancer

RUSCONI

FRIBOURG

Direction and coordination

SCHUEMPERLI

BERN

snRNA expression system for antisense

STADLER

BERN

Tumor targeting with mimotopes

STAHEL

ZUERICH

Chemoprotection against topoII drugs

TRONO

GENEVA

Lentiviruses as gene delivery vectors

VAN MEIR

LAUSANNE

Glyoblastoma (Anti-angiogenic treatment for tumors)

Prof.Sandro Rusconi;

Biochimie, Univ. Fribourg, Pérolles; 1700 Fribourg; CH;
Tel 026 300 8656; Fax 026 300 9735;
e-mail: sandro.rusconi@unifr.ch

Title:

Direction of the NRP37 'Somatische Gentherapie'; tasks and budgets.

Co-applicants:

Collaborators:

D Pedrioli, S B Verca

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Prof. Patrick Aebischer;

Division Autonome de Recherche Chirurgicale; C H U V; Pavillon 3; 1011 Lausanne; CH;
Tel 021 314 24 60; Fax 021 314 24 68;
e-mail: paebisch@chuv.hospvd.ch

Title:

Development of a gene therapy approach for patients suffering from amyotrophic lateral sclerosis.

Co-applicants:

Prof. A. Kato CMU (Genève)

Collaborators:

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Prof Heidi Diggelmann;

Inst. de Microbiologie de l'Université de Lausanne; R. du Bugnon 44; 1011 Lausanne; CH;
Tel 021 314 40 97; Fax 021 314 40 95;
e-mail:

Title:

Development of retroviral vectors targeted to cells of the hematopoietic lineage.

Co-applicants:

Dr. E. Buetti (Lausanne); Dr. P. Meylan (Lausanne); Dr. M. Thali (Lausanne)

Collaborators:

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Prof. Adriano Fontana;

Innere Medizin; Klinische Immunologie; Uni-spital Zürich; Häldeliweg 4; 8044 Zürich; CH;
Tel 01 257 38 13; Fax 01 257 2872;
e-mail: immfoa@usz.unizh.ch

Title:

FAS ligand gene transfer in brain tumor therapy.

Co-applicants:

Collaborators:

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Prof. Felix J.
Frey;

Inselspital; Nephrologie; Departement für Innere Medizin; Freiburgstr.3; 3010 Bern; CH;
Tel 031 632 31 16; Fax 031 632 97 34;
e-mail: felix.frey@insel.ch

Title:

Steroid-mediated gene delivery (SMGD) for therapy of 11beta-hydroxy-steroid dehydrogenase deficiency.

Co-applicants:

Prof. S. Rusconi (Fribourg); Prof. B. Frey (Bern)

Collaborators:

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Dr. Johann
Hossle;

Universitäts-Kinderklinik; Immunologie / Hämatologie; Steinwiesstr.75; 8032 Zürich; CH;
Tel 01 266 73 41; Fax 01 266 71 71;
e-mail: hosslejp@kispi.unizh.ch

Title:

Development of clinically applicable protocols for transitory and permanent somatic gene therapy in chronic granulomatous disease.

Co-applicants:

Prof. R. Seger (Zürich); Prof. S. Rusconi (Fribourg)

Collaborators:

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Dr. Ambros Hügin;

Dermatologie et Vénérologie; Hôpital Cantonal; 24, Rue Micheli-du-Crest; 1211 Genève 14; CH;
Tel 022 372 94 43; Fax 022 372 9470;
e-mail: hugin-ambros@diogenes.hcuge.ch

Title:

Immunotherapy of melanoma; evaluation of anew concept of intra-tumoral gene delivery.

Co-applicants:

Dr. V. Steimle (Genève); Prof. JH Saurat (Genève)

Collaborators:

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Prof. Roman Klemenz;

Universitätsspital Zürich; Pathologie; Schmelzbergstrasse 12; 8091 Zürich; CH;
Tel 01 255 39 31; Fax 01 255 45 08;
e-mail:

Title:

Destruction of tumor-infiltrating blood vessels.

Co-applicants:

PD DR. R Schwendener (Zürich); Dr. D. Moritz (Zürich)

Collaborators:

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Prof. Daniel Kolakofsky;

Génétique et Microbiologie; Centre Méd. Univ.; 9, ave. de Champel; 1211 Genève 4; CH
Tel 022 702 56 57; Fax 022 702 57 02;
e-mail: kolakofs@cmu.unige.ch

Title:

Sendai paramyxovirus as a non-integrative RNA virus vector.

Co-applicants:

Dr. L. Roux (Genève)

Collaborators:

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Dr. Thomas Luchsinger;

Blumenrain 2; 4051 Basel; CH;
Tel 061 261 9106; Fax
e-mail:

Title:

Legal and ethical aspects of gene therapy.

Co-applicants:

Collaborators:

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Prof. Nicolas Mermod;

Lab. Biotechnologie; moléculaire; Département de chimie; EPFL; 1015 Lausanne; CH;
Tel 021 693 6151; Fax 021 693 6140;
e-mail: mermod@iba.unil.ch

Title:

Development of vectors for regulated expression in gene therapy.

Co-applicants:

Collaborators:

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Dr. Jovan Mirkovitch;

ISREC; Chemin des Boveresses 155; 1066 Epalinges; CH;
Tel 021 692 59 20; Fax 021 652 69 33
e-mail: jovan.mirkovitch@isrec.unil.ch

Title:

Faithful regulation of the btk gene for XLA therapy.

Co-applicants:

Collaborators:

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Prof. Karin Mölling;

Institut für Medizinische Virologie; Gloriastr. 30; CH-8028 Zuerich;
Tel 01 634 2652; Fax 01 634 4967;
e-mail: moelling@immv.unizh.ch

Title:

Retroviral vectors for somatic gene therapy.

Co-applicants:

Dr. J. Pavlovic (Zürich)

Collaborators:

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Dr. Walter
Reith;

Génétique et Microbiologie; Centre Méd. Univ.; 9, avenue de Champel; 1211 Genève 4; CH;
Tel 022 702 56 66; Fax 022 702 57 02;
e-mail: reith@cmu.unige.ch

Title:

Construction of mouse models and regulatory systems designed to optimise the control of transgene expression.

Co-applicants:

Prof. JD Vassalli (Genève)

Collaborators:

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PD Dr. Thierry Rochat;

Pneumologie; Dép. de Médecine; Hôpital cantonal universitaire; 1211 Genève 14; CH;
Tel 022 372 95 46; Fax 022 372 99 29;
e-mail: rochat-thierry@diogenes.hcuge.ch

Title:

Somatic gene therapy for cystic fibrosis.

Co-applicants:

Dr. M. Morris (Genève); Prof. S. Suter (Genève); Dr.Marc Chanson

Collaborators:

Dr.Joelle Coclet-Ninin

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Dr. Christoph Rochlitz;

Kantosspital; Abteilung f. Onkologie; Dept Innere Medizin; 4031 Basel; CH;
Tel 061 265 2525; Fax 061 265 5316;
e-mail:

Title:

Clinical and preclinical studies on the use of cytokine-transfected xenogenic cells in the treatment of metastatic cancer.

Co-applicants:

Dr. Med. PY Dietrich (Genève); Prof. Dr. R. Herrmann (Basel)

Collaborators:

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Prof. Daniel Schümperli;

Zoologisches Institut; Entw.biologie; Universität Bern; Baltzerstr. 4; 3012 Bern; CH;
Tel 031 631 46 75; Fax 031 631 41 21;
e-mail: SCHUEMPERLI@ZOI.unibe.ch

Title:

A small-RNA expression system for antisense gene therapy.

Co-applicants:

Collaborators:

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Prof. Beda M. Stadler;

Institut für Immunologie und Allergologie der Universität Bern; Inselspital; 3010 Bern; CH;
Tel 031 632 35 21; Fax 031 381 57 35;
e-mail: stadler@insel.unibe.ch

Title:

Targeting genes to the vasculature of tumours using mimotopes and synthetic antibodies.

Co-applicants:

Dr.Marco G.Cecchini; Dr.George Thalmann; Prof. U. Studer (Departement Klinische Forschung und Urologische Klinik der Universität Bern)

Collaborators:

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Prof. Rolf
Stahel;

Laboratorium für Onkologie; Universitätsspital; Häldeliweg 4; 8044 Zürich; CH;
Tel 01 257 3589; Fax 01 257 2872;
e-mail: onunizh@siak.ch

Title:

Chemoprotection of hematopoietic cells via topoisomerase IIa.

Co-applicants:

S Gasser (Lausanne)

Collaborators:

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Prof. Didier
Trono;

CMU Medecine, 9 Ave Champel, 1211 Geneve, CH
Tel 022 702 5720, Fax 022 702 5721
e-mail: didier.trono@medecine.unige.ch

Title:

A lentiviral vector allowing stable gene transfer in non dividing cells.

Co-applicants:

Collaborators:

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Dr. Erwin
Van Meir;

CHUV; Neurochirurgie; Tumor Biology and Genetics; BH19 - 109; 1011 Lausanne; CH;
Tel 021 314 25 82; Fax 021 314 26 05;
e-mail: erwin.vanmeir@chuv.hospvd.ch

Title:

Integrated therapy for glioblastoma with genes inhibiting angiogenesis.

Co-applicants:

Prof. N. Tribolet (Genève)

Collaborators:

Dr.Mirna Tenan; Dr.Reto Kessler

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