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BACK TO: JOB OFFERS / SEARCHES
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JOB Offer Nr |
NFP37 014, November 2000 |
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Candidate level |
Graduate Student |
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Job Description |
Recombinant DNA Technology |
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Required Skills |
Microbial Genetics & Recombinant DNA Technology |
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Start/ Duration |
From November 2000 till November 2002 |
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Salary |
US$ 5,000 Pper month |
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Contact |
Mr. Onuma Osita, Fidelis, c/o Callistus Chuks Igbudu, Lagos Business School, P.O.Box 73688, Victoria Island, Lagos, Nigeria, Tel:234-1-7745201, Fax: 234-1-7596180, E-Mail: o.osita@mailcity.com |
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Expiration |
One year from date |
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JOB Offer Nr |
NFP37 015, November 2000 |
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Candidate level |
Postdoctoral fellow |
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Job Description |
A posdoctoral position in Gene Therapy is available at the Laval University Cancer Research Center. The host laboratory is located in the downtown area in Quebec City and has state of the art research facilities. The selected candidate will work with an innovative approach to manipulate immune cells. Candidates should have a strong background in molecular biology and a solid publications record. Previous experience with vector construction (adeno or retrovirus-based) and with the preparation/screening of genomic DNA phage libraries will be an asset. |
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Required Skills |
The ability to work in a highly multi-lingual/cultural team. |
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Start/ Duration |
January/February 2001. Duration: 2-3 years |
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Salary |
Inquire |
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Contact |
Interested candidates are advised to send an email to the
electronic address bellow mentioning their career plans,
academic background and key publications. email:
pedro.campos-lima@crhdq.ulaval.ca |
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Expiration |
February 2001 |
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JOB Offer Nr |
NFP37 016, November 2000 |
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Candidate level |
Postdoctoral position |
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Job Description |
A postdoctoral position is available at the Univ.-Children's Hospital as part of our research projects on somatic gene therapy of Chronic granulomatous disease (CGD). The applicant will further develop gene regulatory elements for optimal tissue-specific expression in the myeloid lineage of hematopoiesis after viral gene transfer. The appointment will be for 2 years and is funded by the CGD Research Trust. |
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Required Skills |
Candidates are expected to have a Ph.D. in Cell or Molecular Biology with excellent hands on experience in Molecular Biology techniques. |
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Start/ Duration |
Immediately for 2 years |
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Salary |
According to NF salaries, inquire |
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Contact |
Johann Peter Hossle, Ph.D., Division for
Immunology/Hematology, University Children's Hospital,
Steinwiesstrasse 75, CH-8032 Zurich, Phone: 41-1-266 73 41,
Fax : 41-1-266 71 71 |
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Expiration |
12/2000 |
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JOB Offer Nr |
NFP37 017 |
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Candidate level |
2 graduate student positions (PhD or MD-PhD) |
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Job Description |
We are using derivatives of U7 small nuclear RNA (snRNA) as a means to express stable antisense RNA sequences in the nuclear compartment. By combining with specific proteins to a small nuclear ribonucleoprotein (snRNP), these antisense RNAs accumulate in the nucleoplasm and are ideally suited to modulate the metabolism of specific target RNAs by sterically interfering with interacting molecules such as splicing factors. So far, we have successfully applied this approach to correct splicing defects generated by thalassemic mutations in the b-globin gene (Gorman et al. (1998) Proc Natl Acad Sci USA 95, 4929-4934; Suter et al. (1999) Hum Mol Genet 8, 2415-2423). For this as well as for another, infectious disease-related, project, we have obtained proof of principle in appropriate in vitro cell culture systems. We are currently expanding this approach to test its efficacy in different preclinical contexts. In particular, we are developing lentiviral and other retroviral vector systems that will allow us to deliver the antisense U7 genes into clinically relevant cell populations, and especially into hematopoietic stem cells. |
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Required Skills |
Candidates should hold a Master's degree (or equivalent) in life sciences or a MD or VMD degree and should have a solid background in molecular biology. |
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Start/ Duration |
January 1 and April 1, 2001, respectively |
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Salary |
Salary will be according to standards of the Swiss National Science Foundation. |
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Contact |
Prof. Daniel Schümperli, Institute of Cell Biology, Baltzerstrasse 4, CH-3012 Bern, Switzerland, phone +41 31 631 4675, e-mail daniel.schuemperli@izb.unibe.ch |
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Expiration |
January 1 resp. April 1, 2001 |
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JOB Offer Nr |
NFP37 0xx |
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Candidate level |
xxx |
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Required Skills |
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