TIME

EVENT

Place/Speaker

0830-0900

coffee / registration

Hall Chemistry Building

0900-0915

Welcome addresses

S. Rusconi

0915-1000

Plenary lecture I:
Gene therapy: New hopes, old realities

Inder Verma,
Salk Institute, San Diego CA, USA
Keywords: Adeno-associated vectors, Lentivectors, hereditary disorders, acquired disorders

1000
1005
1010
1015
1020
1025
1030
1035
1040
1045

1105
1110
1115
1120

P01a
P01b
P01c
P02
P03
P04a
P04b
P05
P06
P07a, P07b
COFFEE BREAK
P20a P20b
P08
P09a, P09b
P10

AEBISCHER (Schneider)
AEBISCHER (Deglon)
AEBISCHER (Hottinger)
CECCHINI (Bisoffi)
FONTANA (Ambar)
FREY/Rusconi (Rebuffat)
FREY/Rusconi (Ceppi)
KOLAKOFSKY (Freemann)
ROCHAT (Morris)
STAHEL (Gautschi)

WALTER (Walter)
TRONO (Salmon)
* CATTANEO (Schneider)
* HEMMI (Hemmi)

could not present

P25
P24

KLEMENZ
VAN MEIR

1135-1215

Guest Lecture:
Gene correction and Reprogramming Through Spliceosome-mediated Trans-Splicing

Lloyd Mitchell,
Intronn LLC, Durham NC, USA
Keywords: RNA repair, suicide gene therapy, gene regulation, spliceosome-mediated trans-splicing

1210-1400

Poster session 1, drinks, 1300 lunch

Hall and 'Salle de Lecture', Cafeteria EIF

1400
1410
1420
1440
1510

1530
1610
1630

Statement of the NF referee
M02
M01
P01d,e,f,g,h
M03

M04
M05
M06

Marco Baggiolini
REHMANN-SUTTER (Scully)
*DORSCH-HAESLER
AEBISCHER
HOSSLE (Wasser-Saulnier)

MOELLING (Heinzerling)
MERMOD (Imhof)
SCHUEMPERLI (Schuemperli)

1705-1800

Plenary lecture II:
Gene Correction Of Single Point Mutations Through Chimeroplasts

Clifford Steer,
Univ. Minnesota, Minneapolis MN, USA
Keywords: RNA/DNA oligonucleotide, anionic liposomes, lactosylated PEI, receptor-mediated endocytosis, in vivo hepatic gene delivery, Gunn rat, Crigler-Najjar syndrome type I, Hemophilia B, sickle cell disease, DNA mismatch repair, liver metabolic disorders

1800

Apero

1930

Dinner

TIME

EVENT

Place/Speaker

0830-0900

coffee / registration

Hall Chemistry Building

0900-0915

Welcome addresses

Chairman

0915-1000

Plenary lecture III:
Gene therapy for cancer -the current position

Hardev Pandha,
Hammersmith hospital., Oncology
Keywords: cancer, immunomodulation, prodrug activation, antisense, gene replacement, tumor targeting, systemic vectors

1010
1015
1020
1025
1030
1035
1040
1045

1110
1115
1120
1130
1135

P12
P13
ad hoc
P14
P15
P16
P17
P18a
COFFEE BREAK
P18b
P19
P21
P22
ad hoc

DREHER (NN)
IGGO (NN)
* Scott Lambert (GMP & GLP concepts)
MERLO (Jones)
RÜEGG (Oguey)
OERTLI (Zajac)
VASSALLI (Vassalli)
SCHNEIDER/ Rusconi (Schneider)

SCHNEIDER / Rusconi (Genilloud)
THALI/Filipowicz (Filipowicz)
VILLARD (Villard)
* THOENY (Laufs)
* Una Chen (EU GMP facility?)

could not attend

P11
P23
P26
P27

BAUMGARNTER
MIRKOWITCH
HERRERA
HUEGIN

1135-1215

Guest Lecture 2:
sponsored by MWG biotech
Gene therapy clinical bioanalysis

Michael Grace,
Schering Plough, Union NJ, USA,
Keywords: use of flow cytometry and laser scanning cytometry for the analysis of human clinical surrogate markers in gene therapy trials

1210-1400

Poster session 2, drinks, 1300 lunch

Hall , 'Salle de Lecture', Cafeteria EIF

1400-1440

Plenary lecture IV:
VP22 Protein-mediated delivery applications in gene therapy

P. O' Hare,
Marie Curie Res. Institute, Surrey, UK
Keywords: GFP. intercellular protein trafficking, herpes virus VP22, chimeric proteins

1450
1510

1550

M07a, M07b
M08

M09a, M09b

GAY (Pap)
YANG (Largiader)

*BUEHLER (Buehler)

1615-1710

Closing Lecture:
Angiogenic Gene Therapy with Intramuscular Naked DNA

DW Losordo,
St. Elisabeth Med. Center, Boston, MA, USA
Keywords: VEGF, angiogenesis, endothelium, ischaemic heart disease, myocardium

1720

concluding remarks and welcome to meeting 2000

S Rusconi