Lucas SPIERER, PD, phd


Co-director of the Neurology Unit Laboratory
Director of the Faculty Non-Invasive Brain Stimulation and Imaging platform


Department of Medicine, Neurology, University of Fribourg
Chemin du Musée 5, CH-1700 FRIBOURG
HFR Fribourg – Hôpital cantonal
Chemin des Pensionnats 2-6, Case postale, CH-1700 FRIBOURG

Tel: +41 26 300 85 48  



Research Interests

We focus mainly on training-induced brain plasticity in sensory-cognitive and executive functions. We work with healthy and clinical populations (mostly brain-damaged patients) using neuroimaging, non-invasive brain stimulation and clinical approaches. The overarching aim of our work is to develop efficient neuroplasticity-based rehabilitation strategies, new diagnosis tools and to optimize patients care. Please see my publications for more information.

We share numerous common research projects with Prof Jean-Marie Annoni, notably on the organization of the bilingual brain and neurodegenerative disorders.

I also run the platform for non-invasive brain stimualtion and imaging of the University of Fribourg: NIBSI platform


Key Words

Neural plasticity, cerebral cortex, stroke, learning, executive functions, clinical neurosciences


Social & Bibliometrics profiles



Google Scholar




Swiss National Science Foundation

Novartis Stiftung für medizinisch-biologische Forschung

Pierre Mercier Foundation For Science

Velux Foundation

UNIL Interdisciplinary Research Grants

UNIFR Research Grants



Electrical neuroimaging, transcranial magnetic stimulation, Transcranial Direct Current Stimulation, Neuropsychology, Voxel-based lesion-symptom mapping, functional and structural magnetic resonance imaging



All publications available on request or via Google Scholar or ResearchGate (cf links above)



  • Bernasconi F., De Lucia M., Tzovara A., Manuel A.L., Murray MM., Spierer L.
    Noise in brain activity engenders perception and influences discrimination sensitivity.
    Journal of Neuroscience31(49):17971-17981, 2011 [DOI] [Pubmed
  • Murray M, Spierer L. 
    Multisensory Integration: What you see is where you hear. 
    Current Biology, (Letter), 22;21(6): R229-R23, 2011. [Pubmed
  • Grivel J., Bernasconi F., Manuel A., Murray MM., Spierer L.
    Dynamic recalibration of our sense of time.
    Neuropsychologia49(1): 147-50, 2011. [DOI] [Pubmed
  • At A., Spierer L., Clarke S.
    The role of the parietal cortex in sound localization: a chronometric single pulse TMS study.
    Neuropsychologia49(9): 2794-7, 2011. [DOI] [Pubmed]


  • Bernasconi F., Manuel A., Murray MM., Spierer L.
    Pre-stimulus beta oscillations within left posterior sylvian regions impact auditory temporal order judgment accuracy.
    International Journal of Psychophysiology79(2): 244-8, 2010. [DOI] [Pubmed]
  • Bernasconi F., Grivel J., Murray MM., Spierer L. 
    Plastic brain mechanisms for attaining auditory temporal order judgment proficiency. 
    Neuroimage, 50(3): 1271-1279, 2010. [DOI] [Pubmed
  • Manuel A.L., Grivel J., Bernasconi F., Murray MM., Spierer L. 
    Brain dynamics underlying training-induced improvement in suppressing inappropriate action. 
    Journal of Neuroscience, 30(41): 13670-8, 2010. [DOI] [Pubmed]
  • Bernasconi F., Grivel J., Murray MM., Spierer L. 
    Interhemispheric coupling between the posterior sylvian regions impacts successful auditory temporal order judgments. 
    Neuropsychologia, 48(9): 2579-85, 2010. [DOI] [Pubmed
  • Van de Zwaag W., Gentile G., Gruetter R., Spierer L., Clarke S.
    Where Sound Position Influences Sound Object Representations: a 7T fMRI Study. 
    Neuroimage, 54(3): 1803-11, 2010. [DOI] [Pubmed
  • Spierer L., De Lucia M., Bernasconi F., Grivel J., Bourquin NM., Clarke S., Murray MM. 
    Learning-induced plasticity in human audition: Objects, time, and space. 
    Hearing Research, 271(1-2): 88-102, 2010. [DOI] [Pubmed


  • Murray MM., Spierer L.
    Auditory spatio-temporal brain dynamics and their consequences for multisensory interactions in humans. 
    Hearing Research, 258(1-2): 121-133, 2009. [DOI] [Pubmed
  • Spierer L., Bellmann-Thiran A., Maeder P., Murray MM., Clarke S. 
    Hemispheric competence for auditory spatial representation. 
    Brain, 132: 1953-1966, 2009. [DOI] [Pubmed]
  • Spierer L., Bernasconi F., Grivel J. 
    The temporo-parietal junction as a part of the "when" pathway. 
    Journal of Neuroscience, 29(27): 8630-8632, 2009. [DOI] [Pubmed
  • Spierer L., Bourquin N.M., Tardif E., Murray MM., Clarke S. 
    Right hemispheric dominance for echo suppression. 
    Neuropsychologia, 47(2):465-472, 2009. [DOI] [Pubmed
  • Viceic D., Campos R., Fornari E., Spierer L., Meuli R., Clarke S., Thiran JP. 
    Local landmark-based registration for fMRI group studies of nonprimary auditory cortex.  
    Neuroimage, 44(1): 145-153, 2009. [DOI] [Pubmed]


  • Murray MM., Camen C., Spierer L., Clarke S. 
    Plasticity in representations of environmental sounds revealed by electrical neuroimaging. 
    Neuroimage, 39(2): 847-856, 2008. [DOI] [Pubmed
  • Spierer L., Murray MM., Tardif E., Clarke S. 
    The path to success in auditory spatial discrimination: electrical neuroimaging responses within the supratemporal plane predict performance outcome. 
    Neuroimage , 41(2): 493-503, 2008. [DOI] [Pubmed
  • Tardif E., Spierer L., Clarke S., Murray MM.
    Interactions between auditory 'what' and 'where' pathways revealed by enhanced near-threshold discrimination of frequency and position. 
    Neuropsychologia , 46(4): 958-966, 2008. [DOI] [Pubmed


  • Spierer L., Meuli R., Clarke S.
    Extinction of auditory stimuli in hemineglect: Space versus ear. 
    Neuropsychologia, 45(3): 540-551, 2007. [DOI] [Pubmed
  • De Santis L., Spierer L., Clarke S., Murray MM. 
    Getting in touch: segregated somatosensory what and where pathways in humans revealed by electrical neuroimaging. 
    NeuroImage, 37(3): 890-903, 2007. [DOI] [Pubmed
  • Spierer L., Tardif E., Sperdin H., Murray MM., Clarke S.
    Learning-induced plasticity in auditory spatial representations revealed by electrical neuroimaging. 
    Journal of Neuroscience, 27(20): 5474-5483, 2007. [DOI] [Pubmed
  • Tardif E., Murray MM., Meylan R., Spierer L., Clarke S.
    The spatio-temporal brain dynamics of processing and integrating sound localization cues in humans. 
    Brain Research, 1092(1): 161-176, 2006. [DOI] [Pubmed


Laboratory for cognitive and neurological sciences (LCNS) - Chemin du Musée 5 - 1700 Fribourg - Tel +41 26 300 8539 - Swiss University