Lucas SPIERER, PD, phd


Co-director of the Neurology Unit Laboratory
Director of the Non-Invasive Brain Stimulation and Imaging faculty platform


Department of Medicine, Neurology, University of Fribourg
Chemin du Musée 5, CH-1700 FRIBOURG
HFR Fribourg – Hôpital cantonal
Chemin des Pensionnats 2-6, Case postale, CH-1700 FRIBOURG

Tel: +41 26 300 85 48  



Research Interests

We focus mainly on training-induced brain plasticity in executive functions. We work with healthy and clinical populations (mostly brain-damaged patients) using neuroimaging, pharmacological, non-invasive brain stimulation and clinical approaches. The overarching aim of our work is to develop efficient neuroplasticity-based rehabilitation strategies, new diagnosis tools and to optimize patients care. Please see my publications for more information.

We share numerous common research projects with Prof Jean-Marie Annoni, notably on the organization of the bilingual brain and neurodegenerative disorders.

I also run the platform for non-invasive brain stimualtion and imaging of the University of Fribourg: NIBSI platform


Key Words

Neural plasticity, cerebral cortex, stroke, learning, executive functions, clinical neurosciences


Social & Bibliometrics profiles



Google Scholar




Swiss National Science Foundation

Novartis Stiftung für medizinisch-biologische Forschung

Pierre Mercier Foundation For Science

Velux Foundation

Swiss Foundation for Alcohol Research

UNIL Interdisciplinary Research Grants

UNIFR Research Grants



Electrical neuroimaging, transcranial magnetic stimulation, Transcranial Direct Current Stimulation, Neuropsychology, Voxel-based lesion-symptom mapping, functional and structural magnetic resonance imaging



All publications available on request or via Google Scholar or ResearchGate (cf links above)



  • Bernasconi F., De Lucia M., Tzovara A., Manuel A.L., Murray MM., Spierer L.
    Noise in brain activity engenders perception and influences discrimination sensitivity.
    Journal of Neuroscience31(49):17971-17981, 2011 [DOI] [Pubmed
  • Murray M, Spierer L. 
    Multisensory Integration: What you see is where you hear. 
    Current Biology, (Letter), 22;21(6): R229-R23, 2011. [Pubmed
  • Grivel J., Bernasconi F., Manuel A., Murray MM., Spierer L.
    Dynamic recalibration of our sense of time.
    Neuropsychologia49(1): 147-50, 2011. [DOI] [Pubmed
  • At A., Spierer L., Clarke S.
    The role of the parietal cortex in sound localization: a chronometric single pulse TMS study.
    Neuropsychologia49(9): 2794-7, 2011. [DOI] [Pubmed]


  • Bernasconi F., Manuel A., Murray MM., Spierer L.
    Pre-stimulus beta oscillations within left posterior sylvian regions impact auditory temporal order judgment accuracy.
    International Journal of Psychophysiology79(2): 244-8, 2010. [DOI] [Pubmed]
  • Bernasconi F., Grivel J., Murray MM., Spierer L. 
    Plastic brain mechanisms for attaining auditory temporal order judgment proficiency. 
    Neuroimage, 50(3): 1271-1279, 2010. [DOI] [Pubmed
  • Manuel A.L., Grivel J., Bernasconi F., Murray MM., Spierer L. 
    Brain dynamics underlying training-induced improvement in suppressing inappropriate action. 
    Journal of Neuroscience, 30(41): 13670-8, 2010. [DOI] [Pubmed]
  • Bernasconi F., Grivel J., Murray MM., Spierer L. 
    Interhemispheric coupling between the posterior sylvian regions impacts successful auditory temporal order judgments. 
    Neuropsychologia, 48(9): 2579-85, 2010. [DOI] [Pubmed
  • Van de Zwaag W., Gentile G., Gruetter R., Spierer L., Clarke S.
    Where Sound Position Influences Sound Object Representations: a 7T fMRI Study. 
    Neuroimage, 54(3): 1803-11, 2010. [DOI] [Pubmed
  • Spierer L., De Lucia M., Bernasconi F., Grivel J., Bourquin NM., Clarke S., Murray MM. 
    Learning-induced plasticity in human audition: Objects, time, and space. 
    Hearing Research, 271(1-2): 88-102, 2010. [DOI] [Pubmed


  • Murray MM., Spierer L.
    Auditory spatio-temporal brain dynamics and their consequences for multisensory interactions in humans. 
    Hearing Research, 258(1-2): 121-133, 2009. [DOI] [Pubmed
  • Spierer L., Bellmann-Thiran A., Maeder P., Murray MM., Clarke S. 
    Hemispheric competence for auditory spatial representation. 
    Brain, 132: 1953-1966, 2009. [DOI] [Pubmed]
  • Spierer L., Bernasconi F., Grivel J. 
    The temporo-parietal junction as a part of the "when" pathway. 
    Journal of Neuroscience, 29(27): 8630-8632, 2009. [DOI] [Pubmed
  • Spierer L., Bourquin N.M., Tardif E., Murray MM., Clarke S. 
    Right hemispheric dominance for echo suppression. 
    Neuropsychologia, 47(2):465-472, 2009. [DOI] [Pubmed
  • Viceic D., Campos R., Fornari E., Spierer L., Meuli R., Clarke S., Thiran JP. 
    Local landmark-based registration for fMRI group studies of nonprimary auditory cortex.  
    Neuroimage, 44(1): 145-153, 2009. [DOI] [Pubmed]


  • Murray MM., Camen C., Spierer L., Clarke S. 
    Plasticity in representations of environmental sounds revealed by electrical neuroimaging. 
    Neuroimage, 39(2): 847-856, 2008. [DOI] [Pubmed
  • Spierer L., Murray MM., Tardif E., Clarke S. 
    The path to success in auditory spatial discrimination: electrical neuroimaging responses within the supratemporal plane predict performance outcome. 
    Neuroimage , 41(2): 493-503, 2008. [DOI] [Pubmed
  • Tardif E., Spierer L., Clarke S., Murray MM.
    Interactions between auditory 'what' and 'where' pathways revealed by enhanced near-threshold discrimination of frequency and position. 
    Neuropsychologia , 46(4): 958-966, 2008. [DOI] [Pubmed


  • Spierer L., Meuli R., Clarke S.
    Extinction of auditory stimuli in hemineglect: Space versus ear. 
    Neuropsychologia, 45(3): 540-551, 2007. [DOI] [Pubmed
  • De Santis L., Spierer L., Clarke S., Murray MM. 
    Getting in touch: segregated somatosensory what and where pathways in humans revealed by electrical neuroimaging. 
    NeuroImage, 37(3): 890-903, 2007. [DOI] [Pubmed
  • Spierer L., Tardif E., Sperdin H., Murray MM., Clarke S.
    Learning-induced plasticity in auditory spatial representations revealed by electrical neuroimaging. 
    Journal of Neuroscience, 27(20): 5474-5483, 2007. [DOI] [Pubmed
  • Tardif E., Murray MM., Meylan R., Spierer L., Clarke S.
    The spatio-temporal brain dynamics of processing and integrating sound localization cues in humans. 
    Brain Research, 1092(1): 161-176, 2006. [DOI] [Pubmed


Laboratory for cognitive and neurological sciences (LCNS) - Chemin du Musée 5 - 1700 Fribourg - Tel +41 26 300 8539 - Swiss University