DÉPARTEMENT DE MÉDECINE
DEPARTEMENT FÜR MEDIZIN
DEPARTMENT OF MEDICINE

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Principal Investigator

MONTANI Jean-Pierre

Full Professor of
Physiology

jpm

       
 
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  Research Topics • Cardiovascular physiology
• Metabolism
 
       
  Subtopics • Cardiovascular and renal complications of weight cycling
• Control of blood pressure and regulation of sodium balance
• Impact of nutrition and salt on cardiovascular and metabolic control
• Mathematical modelling of large integrative physiological systems
• Mechanisms of obesity-induced hypertension
• Regulation of energy metabolism by the kidney
 
       
 

Questions addressed

The main research interest of the laboratory is to study the control mechanisms that regulate blood pressure, cardiac output and energy metabolism, with particular emphasis on the effects of obesity and nutrition. Animal and human physiological experiments are conducted to analyze:
► The impact of weight cycling on fat accumulation and cardiovascular risks factors
► The mechanisms by which weight gain leads to an increase in blood pressure
► The interaction between sugar, fat and salt in developing metabolic and cardiovascular risk profiles
► The effects of caffeinated soft drinks on cardiovascular and autonomic regulation. In addition, the role of the kidney in regulating whole body metabolism is analyzed with the study of uninephrectomized animals, to test whether decreased renal function can promote a metabolic syndrome

 
       
  Keywords • Autonomic nervous system
• Blood pressure
• Human and Animal Physiology
• Hypertension
• Obesity
• Soft drinks
• Weight cycling
 
       
  Contact Email address jean-pierre.montani [at] unifr.ch  
       
  Personal site Physiology ► Group Montani  
   

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University of Fribourg  •  Faculty of science  •  Department of Medicine  •  Ch. du Musée 8  •  CH-1700 Fribourg
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